偏头痛的

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

I am thinking of the fanatical asceticism of Simone Weil's life, her contempt for pleasure and for happiness, her noble and ridiculous political gestures, her elaborate self-denials, her tireless courting of affliction; and I do not exclude her homeliness, her physical clumsiness, her migraines, her tuberculosis.

我现在正在思考这样一系列问题：西蒙娜·薇依狂热的禁欲主义生活方式，她对愉悦和幸福的蔑视，她高尚而可笑的政治姿态，她的偏头痛，她的肺结核。

Concerning about the closed noninteractive literature-based KDD system, whose aim is to validate whether do exist logical relation between "Raynaud"s syndrome /fish oil" and "migraine headache/magnesium to test the feasibility of the arithmetic of the closed noninteractive literature-based KDD.

闭合式知识发现过程，目的是通过书目不相关联的"雷诺氏病／鱼油"、"偏头痛／镁"之间的逻辑关联的存在性，验证本文采用的闭合式知识发现算法在汉语文献中的可行性，若可行，则闭合式知识发现系统可以用来验证开放式知识发现系统提出的假设是否准确。

Results:All dosage groups of Tou-Yu-Tong Pills could release chronic nerve injury caused by formaldehyde solution; remarkedly inhibit the pain of mice in the formalin test and prolong the latencies of paw-licking. It could significantly diminish pain caused by glacial acetic acid ,reduce the number of the writhing in mice.To the model of migraine ,Tou-Yu-Tong Pills can improve the content of 5-HT in brain tissue of mice ,and ruduce 5-HTAA.

结果 头愈痛丸对福尔马林致小鼠慢性神经性疼痛反应，能明显减少动物舔后足的时间，改善其伤害性疼痛行为反应；对冰醋酸致小鼠扭体反应，能显著延长扭体的潜伏期，减少扭体反应的次数；对小鼠偏头痛模型，能显著升高小鼠脑内5-HT的含量，且降低5-HIAA的趋势。

These findings have no implications for the out-of-body experience as it relates to near-death experiences, Dr. De Ridder said. Spontaneous out-of-body experiences have also been previously reported in epileptic patients, those with migraine, and, in a recent report, have been induced in healthy volunteers using a virtual-reality system, although not in this kind of reliable way.

De Ridder医师表示，这些发现并不如濒死经验那样的有关联，自发性的灵魂出窍体验过去也曾于癫痫病患、偏头痛病患身上发现，且在最近的一项报告中，也曾在一位使用虚拟实境系统的健康自愿者身上看到，虽然并不是以像这样可靠的方法证实。

These findings have no implications for the out-of-body experience as it relates to near-death experiences, Dr. De Ridder said. Spontaneous out-of-body experiences have also been previously reported in epileptic patients, those with migraine, and, in a recent report, have been induced in healthy volunteers using a virtual-reality system, although not in this kind of reliable way.

De Ridder医师表示，这些发现并不如濒死经验那样的有关联，自发性的灵魂出窍体验过去也曾於癫痫病患、偏头痛病患身上发现，且在最近的一项报告中，也曾在一位使用虚拟实境系统的健康自愿者身上看到，虽然并不是以像这样可靠的方法证实。

"With stroke, there is strong circumstantial evidence of a link, and we need better characterization of the types of PFO that we are dealing with," he said."With respect to migraine, there is circumstantial evidence of a link in patients with migraine and visual aura and large shunts, and there is strong anecdotal evidence of a therapeutic effect."

&与中风，有很强的旁证证明二者之间的联系，我们需要更好地特征描述我们正在处理的PFO类型，&他说到，&就偏头痛而言，我们有旁证——在出现视觉先兆和巨大分流的患者当中，确实存在联系，并且在治疗效果上也有观察性的证据。&

Coincident with the rise of the internet has been a rise in the number of resources available to those who are living with the wracking pain of migraine.

巧合与互联网的兴起已成为数目的增加，可利用的资源，这些是谁的生活与wracking疼痛的偏头痛。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。