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Here, we report the patterns derived from the analysis of 39 histone modifications in human CD4 T cells.

这里,我们报告了来自于人类CD4细胞中39个组蛋白修饰的分析的模式。

We will discuss methods to address these challenges in the context of analyzing histone modifications and DNA methylation data.

我们将在分析组蛋白修饰和DNA甲基化数据的背景下,讨论解决这些挑战的方法。

Histone modifications play a complex role in the regulation of transcription.

组蛋白修饰是转录调节中的一个重要环节。

There has been no comprehensive data repository that is exclusive for human histone modifications.

没有专门适合于人类组蛋白修饰的综合的数据仓库。

Mining and integration of histone modification data can be beneficial to novel biological discoveries.

组蛋白修饰数据的挖掘和整合能够有益于新颖的生物学发现。

Alterations in histone modifications may be linked to human diseases especially cancer.

组蛋白修饰的改变可能与人类疾病有关联,特别是癌症。

Different modifications may combine to form complex "histone codes."

不同的修饰可能联合起来形成复杂的"组蛋白编码"。

Our data suggest that these histone modifications may act cooperatively to prepare chromatin for transcriptional activation.

我们的数据表明,这些组蛋白修饰可能共同作用于染色质的转录激活。

Therefore, we developed a relatively comprehensive database for human histone modifications.

因此,我们为人类组蛋白修饰开发了一个相对综合的数据库。

In this way, histone modifications have the potential to influence many fundamental biological processes, some of which may be epigenetically inherited.

在这种方法中,组蛋白修饰具有影响很多基本生物学过程的潜力,它们中的一些可能是表观上遗传的。

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She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了,但同意作为朋友相处。

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要是在劳改农场,你等着挨绳子吧!

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本文综合考虑了几种电弧重燃和熄灭理论。