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Methods Four three-dimensional finite element models were constructed by the data of spiral CT:1Mandibular second premolar restored directly by full crown;2Fill the perforating cavity with resin material and full crown restoration;3Cast nickel chromium alloy post core plus full crown restoration;4Fiber post and resin core plus...

方法采用螺旋式CT扫描获取数据,建立下颌第二前磨牙4种情况下的三维有限元模型:1直接全冠修复;2用树脂材料充填开髓洞形后全冠修复;3铸造镍铬合金桩核与全冠修复;4纤维桩树脂核与全冠修复。

The physical fundus restoration technology includes stability designing and topographical reforming of physical fundi.

湖滨带物理基底修复工艺包括物理基底稳定性设计和物理基底地形、地貌的改造;生物配制工艺包括生态恢复全系列工艺和半系列a、b工艺;巢湖东端湖滨带生态修复工程方案包括物理基底修复方案、生态修复工程、景观工程设计和生态观测场建设工程。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病,不管是急性淋巴性白血病或是急性骨髓性白血病,在染色体11q23部位有染色体易位的情况;这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是,单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%;并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且,这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后,而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖,遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以,白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

The artifical fillers are hung under the plant floating bed then the remedial system combined by plant and microorganism came into being. The remedial effectiveness of the system was visibly better than that of the phytoremediation alone. So when the temperature is higher the remedial system combined by plant and microorganism is the preferable remedial technique to remedy contaminated water. In autumnal end and winterly outset, the temperature is lower, the plants begin to fade and die, and the plant must be harvested lest the relict of plant should contaminate water again. At the same time the technique combined by immobilized nitrogen cycling bacteria and microorganism which already existed in the water was used to remedy contaminated water.

将人工填料悬挂于植物浮床下,形成植物和微生物相结合的修复系统,其修复效果明显好于单独植物修复技术,因此温度较高时用植物和微生物共同结合的生物修复技术修复水体污染;秋末冬初温度较低时,植物开始死亡,必须将植物收割,以免植物残体造成二次污染,此时用固定化氮循环细菌和水体中原有微生物相结合的技术来修复水体的污染。

Though not energy-related,theCanal Restorer'' on the Baima Canal in southern China was arguably one of the most successful out -of-the-box international case studies presented at Green Build.0n an urban stretch of canal,Ocean Arks International of Burling on,Vermont,designed and installed a 110aung walkway system to treat waste generated by an equivalent of 12,000 people.

虽然不能源-相关的,那运河修复的人''在中国南部的 Baima 运河上可以说在外是最成功的之一--那-在格林呈现的盒子国际的个案研究建立。运河的都市伸展,大海方舟国际的去掉节在,之上佛蒙特州,设计了而且安装了一个 110aung 走道系统对待废弃的被一个等同于 12,000个人产生。

Conclusions— The most powerful histological predictor of stent thrombosis was endothelial coverage. The best morphometric predictor of LST was the ratio of uncovered to total stent struts. Heterogeneity of healing is a common finding in drug-eluting stents with evidence of LST and demonstrates the importance of incomplete healing of the stented segment in the pathophysiology of LST.

支架内血栓的最强的组织学预测因子是支架的内皮覆盖程度;最佳的LST形态学预测因子为未被内皮覆盖支架丝与总的支架丝的比值;内皮修复的不均一性在置入DES后发生LST的患者中是常见的,证明了支架节段内内皮覆盖不全在LST病理生理机制中的重要性。

Conclusions— The most powerful histological predictor of stent thrombosis was endothelial coerage. The best morphometric predictor of LST was the ratio of uncoered to total stent struts. Heterogeneity of healing is a common finding in drug-eluting stents with eidence of LST and demonstrates the importance of incomplete healing of the stented segment in the pathophysiology of LST.

支架内血栓的最强的组织学预测因子是支架的内皮覆盖程度;最佳的LST形态学预测因子为未被内皮覆盖支架丝与总的支架丝的比值;内皮修复的不均一性在置入DES后发生LST的患者中是常见的,证明了支架节段内内皮覆盖不全在LST病理生理机制中的重要性。

Let's sum up the experience of their ancestors in the global financial crisis was also reflected in one: When the stock, bond, agricultural products (15.93,-0.57,-3.45%, right), metals, energy Yixieqianli, but Gold or not the anti-up, and other things and then drop the more serious when the higher gold on the rise, although the "currency war" there are a lot of controversy, but the author also put forward a very troubling subject people - in the note before Gold has always been recognized as the world's hedge the last choice, after the collapse of national gold standard through a variety of monetary and material readiness to carry out risk reserves, and individuals can not repair a crude oil storage keep it?

让我们加快他们的祖先在全球金融危机的经验总结也反映在1:当股票,债券,(15.93,-0.57,-3.45%,农产品右),金属,能源Yixieqianli,但黄金或不反了,和其他的东西,然后下降,更严重时,社会上越来越高的黄金,虽然&货币战争&有许多争议,但作者还提出了一个非常令人不安的问题的人-前的说明黄金一直被公认为世界上的对冲后,国家黄金标准通过金钱和物质准备各种崩溃最后的选择,进行风险准备金,个人不能修复的原油储存保持下去吗?

For maintain the genome integrity and fidelity. DNA repair processes are classified into pathways responsible for repairing specific classes of DNA damage, although recent data indicated that some proteins function in multiple pathways. Base excision repair occurs through excision of a damaged region, followed by fill-in repair synthesis using the opposite strand as a template. Mismatch repair operates on base mismatched and small loop-outs that arising during replication by misincorporation or slippage on the template strand. Nucleotide excision repair removes photoproducts from u.v. radiaton and bulky adducts from a multiple of chemicals. DNA double-strand breaks may be rectified by either homologous recombination repair and nonhomologous end joining pathways where both strands of the DNA duplex are damaged.

DNA修补基因可藉由不同的机制对不同程度的DNA损害进行修复,虽然近来已有文献指出,一些DNA修复蛋白可能参与多种DNA修复机制,不过一般可分为下列四种DNA修复机制:碱基删除修复(Base Excision Repair; BER),即对较小的DNA损伤,进行修复;核苷酸错误配对删除修复,即对复制时所产生的核苷酸配对错误或模板滑动造成的DNA损害进行修复;核苷酸删除修复(Nucleotide Excision Repair; NER),即对因紫外线或有机化合物所造成的较大损伤进行修复;以及双股DNA断裂修复(Double-Strand Breaks; DSBs),即对双股DNA断裂进行修复,此机制又可分为同源染色体的重组与末端接合两种主要路径,对受损的DNA进行修复。

Methods A total of 56 patients (172 teeth) were randomly divided into two groups: in the experimental group, 30 patients of 86 teeth were restored with IPS Empress 2 all porcelain crown restoration; and in the control group, 26 patients of 86 teeth were restored with nichrome baked ceramic crown.

目的 评价IPS Empress 2全瓷冠修复技术修复上颌前牙的临床效果。方法将56例患者172颗牙分成两组,试验组30例86颗牙,以IPS Empress 2全瓷冠修复技术修复;对照组26例86颗牙,以镍铬合金烤瓷冠修复。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力