信息学

The interest in applying informatics techniques to both clinical problems and problems in basic science can be traced to the Dendral project in the 1960s.

临床问题和基础科学中的问题在应用信息学技术中的兴趣可以追溯到1960年代的Dendral计划。

In this paper, the result showed that iron is relative to the growth and pathogencity of the pathogen Erwinia carotovora var. carotovora and Erwinia carotovora subsp. atroseptica. And then the related genes to iron metabolism are found and analyzed by bioinformatics method.

本文通过实验证明了铁与植物病原细菌Erwinia carotovora var.carotovora和Erwinia carotovora subsp.atroseptica的生长与致病性的关系，利用生物信息学方法查找和分析了Eca中与铁代谢相关的基因。

Porcine hemoglobin polymer is made in imitation as the substtitute for blood product. Pseudorabies virus is chosen as the enveloped DNA model virus and the Porcine Parvovirus is chosen as the nonenveloped DNA model virus. Complete DNA sequences of these two kinds of virus are analyzed and specific fragments are selected as examinable targets. Establish a new method based on real time PCR combined with cell infection assay to evaluate virus clearance efficiency in blood product.A new method is established to remove the virus from blood product.

本研究以戊二醛聚合猪血红蛋白模拟血液制品，选取PRV、PPV分别作为血液制品中有包膜DNA指示病毒和无包膜DNA指示病毒，针对特定两种指示病毒PRV、PPV，进行了生物信息学分析，选取特定片段作为扩增靶点进行检测，建立了一种基于实时荧光定量PCR技术的检测方法，联合病毒的细胞感染力实验，用以评价血液制品中指示病毒的灭活去除效率。

This papersummarizes the studies on glycinin including components,structure and gene families.The homogeneity of the glycinin gene sequences was compared by bioinformatics.Heredity Distances of the six glycinin genes were analyzed. Special emphasis is laidupon comparing the sequences and components of amino acids in the glycinin. Thecontents of major amino acids in the intact glycinin and in the acid and basic peptideswere analyzed. In view of others and our researches, we advance some new thinkingand tactics of improving rice nutritional quality by using glycinin genes.

本文在简要介绍大豆球蛋白组分、结构及基因家族后，采用生物信息学方法分析比较了不同种类大豆球蛋白基因之间的序列同源性，并对不同大豆球蛋白基因的遗传距离作了分析；本文还重点比较分析了不同大豆球蛋白的氨基酸序列和组成，以及不同酸性肽和碱性肽中重要氨基酸的含量，基于对前人工作的总结和我们的分析结果，本文提出了利用大豆球蛋白基因进行水稻营养品质改良研究的新思路和新策略。

Using RT-PCR and RACE methods,5′ up stream and 3′down stream cDNA sequence of ABP1 were isolated from Gossypium hirsutum for the first time.

测序及生物信息学分析表明，该基因cDNA全长824 bp编码190个氨基酸，它所编码的氨基酸序列包含植物ABP1蛋白家族的所有特征，被命名为GhABP1。

In order to understand the preliminary characteristics of transcripts and provide resources for the SSR marker study in the Haliotis discus hannai, we have an analysis of tandem repeats based on 5 784 ESTs downloaded from NCBI.

SSR功能性标记奠定基础，我们利用生物信息学手段对NCBI公共数据库中的5784条皱纹盘鲍EST序列进行EST-SSR特征分析。

Bioinformatics Analysis of Silkworm Development-Related Genes According to sequence homology, homologous genes for 86 genes participating in embryonic development genetic hierarchy of Drosaphila were searched in silkworm genome, including 43 maternal genes, 12 gap genes, 9 pair rule genes, 13 segment polarity genes and 9 homeotic genes. Results show that all but 6 maternal genes have the homologues in silkworm genome and some of them have high similarity.

家蚕发育相关基因的生物信息学分析基于序列的相似性，在家蚕基因组数据中检索参与果蝇胚胎发育调控级联的86个重要基因的同源基因，结果表明，除6个母性基因在家蚕中没有找出同源基因外，其余基因在家蚕中均存在同源基因，并且其中一部分具有相当高的相似性。

Currently, Chinese delegations take part in IMO, IBO, IChO, IPhO and IOI every year and often achieve excellent results.

目前每年由中国科协组队参加国际数学、生物、化学、物理、信息学奥林匹克竞赛，成绩优异。

Methods By the bioinformatics analyzing tools in bioinformatics webs site,a Ta CRISP 2 fulllength gene from the Taenia saginata asiatica fulllength cDNA plasmid libratory was identified and the coding region sequence and the characteristics of the deduced protein were analyzed.The coding region of Ta CRISP was amplified with PCR,endonuclease digestion and cloned into the prokaryotic expression vector pET30a and then expressed in E.coli BL21 with IPTG induction.

用生物信息学方法从亚洲牛带绦虫成虫全长cDNA质粒文库中识别TaCRISP的全长编码基因并预测编码蛋白质的各种结构与功能；将其编码区序列克隆到原核表达载体pET-30a上，测序鉴定重组质粒，之后进行诱导表达，表达产物经十二烷基磺酸钠-聚丙烯酰胺凝胶电泳鉴定。

Now, I mainly engaged in myxobacterial genomic and bioinformatics analysis work. Myxobacteria is a single-cell microorganisms, but they act as multi-cell behavior (such as feeding, social movement, cells congregating and fruiting body formation, and so on) and own a wealth of secondary metabolites Product, those remarkable characteristics make myxobacteria important in the research fields of prokaryotes cell differentiation and development, biological evolution, as well as the drug development and research.

现主要从事粘球菌基因组与生物信息学分析方面的研究工作：粘细菌是单细胞微生物，然而却具有多细胞行为（如摄食、社会性运动、细胞聚集和子实体形成等）和丰富的次级代谢产物，这些行为特征使粘细菌在原核生物的细胞分化发育、生物进化以及药物开发研究中占有重要地位。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。