信息学

Objective To examine the important roles of microRNAs in regulating amphid structure and function, we performed a computational analysis for the genetic loci required for the sensory perception and their possibly corresponding miRNAs in C.

目的 为了系统评价microRNA在调控化学传感器结构和功能方面的重要作用，我们进行了线虫中有关影响化学传感器结构与功能的遗传位点以及和其可能对应的miRNA的生物信息学分析。

That means Pho85 kinaseand calcineurin were involved in salt tolerance with an identical target protein or in 中科院上海生化与细胞所博士学位论文摘要 the same pathway. Inhibition of calcineurin decrease the YPH499, pho80? mutant,and pap1 (pcl7)? mutant Mn2+ tolerance but not that of pho85? mutant and thepho85? mutant was more sensitive to Mn2+ than YPH499, pho80? mutant, and pap1(pcl7)? mutant even with the addition of cyclosporin A. Therefore, the conclusioncould be drawn that PHO85 gene played a dominant role in Mn2+ homeostasisregulation in compare with calcineurin. As for Ca2+ tolerance, cyclosporin A canincrease the tolerance to Ca2+ of all the mutant mention above, that means Pho85kinase and calcineurin function antagonistically in regulation of Ca2+ homeostasis.In Bioinformatics, BRI3 gene is a novel gene without any function clue but givehigh conservation in mammalian.

我们通过钙调磷酸酶的特异抑制剂环孢菌素A研究了YPH499、+2+pho85缺失株、pho80缺失株、pap1缺失株在钙调磷酸酶失活后对Na、Mn、2+Ca金属离子敏感性的变化，结果显示Pho85蛋白激酶和钙调磷酸酶通过直接+或间接激活同一个靶蛋白或途径来增强细胞对Na的耐受；和钙调磷酸酶相比，2+PHO85的缺失对酵母细胞Mn耐受性的破坏是相对控制性的，钙调磷酸酶的失2+活不能进一步降低pho85缺失株对Mn的耐受能力；Pho85和钙调磷酸酶在对2+Ca的耐受调节中是相互拮抗的，钙调磷酸酶的失活能增加pho85缺失株和2+pho80缺失株的Ca耐受。i中科院上海生化与细胞所博士学位论文摘要对本实验室克隆的人新基因BRI3进行系统的生物信息学分析，发现它是一个在哺乳动物中保守的，但功能未知的基因。

In order to study functions of glutathione S-transferase theta during preparation and synthesis of fibroin in Antheraea pernyi, expression of GSTT in silk glands of the fifth instar larvae was analyzed.

为明确柞蚕谷胱甘肽硫转移酶－theta在柞蚕丝素蛋白准备和合成过程中所起的作用，采用生物信息学的方法克隆了柞蚕GSTT基因，并分析其在5龄幼虫丝腺中的表达规律。

To enrich the molecular biology information of Antheraea pernyi nucleopolyhedrovirus, the p11 gene was PCR amplified and cloned. Moreover, the sequence was subjected to bioinformatics analysis.

为丰富柞蚕核型多角体病毒分子生物学基础，通过PCR扩增克隆了ApNPVp11基因并进行了序列的生物信息学分析。

Bioinformatic resources related to Arabidopsis thaliana will be used to illustrate these approaches.

与拟南芥相关的生物信息学资源将被用来阐明这些方法。

The results demonstrate that SarA regulated directly the expressions of lipA, zinC and atlE by protein-DNA binding to the promoter region of AT-rich sequence.

生物信息学分析表明，SarA控制atlE，lipA和zinC 3种基因表达可能是通过与被调控基因上游的特定DNA序列的结合来实现的，该DNA结合区保守并富含AT碱基。

The research of the correlation between TCM Syndrome and genome is just exploring the bimolecular background of TCM syndrome using the method of bioinformatics.

中医证候－基因组研究即是借用了生物信息学的方法来探索中医证候的生物学本质。

They are accurate imaging deep reflectors in difficult areas information theory of seismic wavefield and direct prediction of burred oil and gas fields via geophysical data .

本文讨论当前我国深层油气地震勘探面临的难题及基础研究的三个主攻方向，包括：困难地区深层地震反射体准确成像，地震波场信息学，油气田直接预测的地球物理方法技术等

cdc42-1ike protein gene was screened from the cdna library of adult clonorchis sinensiswith bio-informatics method.

应用生物信息学方法从华支睾吸虫成虫cdna文库中筛选出cdc42样蛋白基因。

The TC gene was screened from cDNA library of adult Clonorchis sinensis, cloned, expressed and purified. The purified protein of TC gene will be of importance for further research on the biological function of the gene.

通过生物信息学方法由华枝睾吸虫成虫cDNA文库中筛选出TC基因，并成功予以克隆，表达及纯化。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。