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In 10 ppm , I 4 promoted slightly growth of Cole root; In 10 ppm or 100 ppm, i6 promoted slightly growth of Stalk of barnyard grass.

在10ppm时,Ⅰ_4对油菜根有较弱的促进生长作用;在10ppm或100ppm时,Ⅰ_6对稗草的茎均有较弱的促进生长作用。

It's able to accelerate the growth of corium, accelerate the activation of cell and accelerate the regeneration of epithelium.

具有良好的促进伤口愈合的作用,能促进肉芽生长并促进细胞活化,促进上皮细胞再生。

The inhibitive effect of 1, 2-benzenedicarboxylic acid on the absorption of N, P and K increased with its concentration rising. Low concentration of dibutyl phthalate increased the absorption of N, but decreased the absorption of P and K. Its high concentration restrained the absorption of N, P and K, while the low concentration of diphenylamine could stimulate the absorption of N and K, but restrain the absorption of P.

随着邻苯二甲酸浓度的增加,其对番茄幼苗根系吸收N、P、K的抑制作用增强;低浓度的邻苯二甲酸二丁酯可以促进番茄幼苗根系对N的吸收,抑制对P、K的吸收,高浓度时对N、P、K的吸收均起抑制作用;低浓度的二苯胺可以促进番茄幼苗根系对N、K的吸收,抑制对P的吸收。

Results showed that L-THP possessed negative inotropic and negative chronotropic action, lowed left ventricular pressure and it's infinitesimal calculus, decreased heart output in per min., shorten 〓 and 〓 of action potential of ventricular papillary muscle of guinea pig and even the plate-phase of action potential disappeared in larger dose group , but prolonged 〓. we studied transmembrane transportation of 〓 after administering L-THP , L-THP not only depressed uptake and increased release of Ca 2+ in normal myocardium, but also it showed stronger inhibition in cell injured by ISO, and fully eliminated the effect of ISO increasing uptake and decreasing release of 〓. By detecting the 〓 content of ventricular single myocyte using fluorescent probe Fluo-3/AM, results correspond to that done above, L-THP decreased 〓 content inside of cell significantly. Using whole-cell mode, we observed the effect of L-THP on Ica in ventricular single cell, it was found that L-THP decreased Ica, the effect increased with increasing it's dose, and had voltage, frequency-dependency. Dose highly corelated to effect, corelative constant is 0.87. When washing cell with normal tyre's solution, Ica could recover, which proved the blocked action of L-THP on calcium channel once again. Meanwhile, L-THP reduced production of MDA in heart injured by ISO in dose-dependent manner, improved content of GSH-Px, in case tissue or cell free from free radical damage.

结果显示,该药物具有负性肌力和负性频率作用,降低左室压及其微分,终使每分心输出量减少;缩短豚鼠心室乳头肌动作电位时程的〓和APD〓,大剂量使动作电位平台消失,〓延长;同位素示踪法研究证实L-THP抑制〓摄取,促进〓释放,降低细胞内的〓含量;单通道水平的研究证实,L-THP减少豚鼠心室肌单细胞内向钙电流,且具有剂量,电压,频率依赖性,其作用易于洗脱,药物剂量与Ica也具有高度相关性(相关系数r为-0.87);L-THP还可抑制ISO损伤心肌组织所致的丙二醛含量增加,增加谷胱甘肽过氧化物酶的量,使组织细胞免受损伤。L-THP阻断L-型〓通道,抑制〓的摄取,促进〓的释放,降低细胞内〓含量L-THP作用的离子基础。

The Chinese compound prescription can improve the bone formation and prevent bone loss via inhibiting bone absorption and improving ossify,bone mineral deposition and mineralization as well as increasing BMD,which leads to prevention and treatment of bone loss.

中药复方能明显促进骨形成作用,有效抑制骨吸收作用,减弱溶骨过程从而促进骨矿盐的沉积和矿化,增强BMD而达到防治骨丢失的作用;有效的防护和治疗失重性骨丢失采取联合措施很有必要。

To investigate the effect of p38MAPK signal conducting pathway on livercancinoma cell's malignant phenotype induced by VEGF,we take theexperiment with cell growth test,scanning microscope and laser scanningconfocal microscope so that observe effect of p38MAPK signal conductingpathway on liver cancinoma cell growth,pseudopodium formation andframework of cytoskeleton induced by VEGF.results indicate that the cellbecame ellipse and there were more and thick pseudopodium in the cell'ssurface after being treated by VEGF,and destroyed framework ofcytoskeleton,which can be blocked by pretreated with a special inhibitor ofp38MAPK SB203580 so that VEGF promote metastasis by enhancing livercell migration and movement via p38MAPK signal conducting pathway,butVEGF promote cell growth without p38MAPK signal conducting pathway.

为进一步探讨VEGF通过p38信号传导通路诱导肝癌细胞转移时,对肝癌细胞恶性表型的影响,采用细胞增殖实验、扫描电子显微镜、激光扫描共聚焦显微镜观察VEGF对肝癌细胞增殖作用、细胞伪足形成、细胞骨架微丝结构的影响以及p38MAPK信号通路调控作用。结果显示,VEGF能够不通过p38信号通路促进肝癌细胞增殖;VEGF诱导肝癌细胞丝状伪足增多、增长,使细胞骨架微丝结构破坏、甚至消失。阻断p38MAPK信号通路,可以抑制VEGF诱导的肝癌细胞伪足形成,细胞骨架丝状结构呈束状,排列较规整。上述结果表明,VEGF可以通过p38信号传导通路诱导肝癌细胞伪足增多、增长,促使细胞骨架微丝结构破坏,使肝癌细胞迁移、运动能力增加,促进肿瘤转移。VEGF并不通过p38信号通路诱导肝癌细胞增殖作用。

The serum levels of TChE and SOD and CAT in hippocampus of mice in Cold group was also significantly higher than those in the Control group and Warm group(P 0.05或P 0.01),while the serum level of MDA in the Control group and Warm group were higher than that in the Cold group(P 0.05或P 0.01). Conclusion:(1)Long proper winter swimming could improve learning and memory abilities of mice.(2) Winter swimming could improve the ability of learning and memory by coordinate the content of acetylcholinesterase (3) This effect may be related to the decreased activity of TChE and the increased activity of anti-oxidatio.

1长期适量的冬泳运动可以促进小鼠学习记忆能力。2冬泳运动可以通过增加小鼠脑内海马组织中ACh的含量而影响TChE的活力。3冬泳运动促进学习记忆的机制可能是:3.1冬泳运动通过冷应激引起的神经内分泌系统的反应,来改变中枢神经系统的功能,使小鼠脑内乙酰胆碱的代谢增强、含量增加,从而促进学习记忆能力。3.2冬泳运动通过增强机体清除自由基的能力,来减轻脂质过氧化的程度,对小鼠的脑损伤起到保护作用,从而促进学习记忆能力。

Conclusions1、E_2 may induce the apoptosis and Fas,FasL expressions of Jurkat cell,its effect positively related to the dose and treating time of E_2.2、There is intrinsic co-expression of ERαand ERβon Jurkat cell,which can be upregulated by E_2,positively related to E_2 doses.3、E_2 may act as an apoptosis inducer of Jurkat cell via ERβ.4、E_2 can promote the transcriptive activity of NF-κB in Jurkat cell.The increased NF-κB activity may lead to increased apoptosis of Jurkat cell.

结论1、E_2可增加Jurkat细胞的凋亡,并增加Fas、FasL的蛋白表达,且其作用与E_2的剂量和处理时间呈正相关。2、Jurkat细胞上存在ERα、ERβ的表达,且E_2可上调这两种受体的表达,E_2剂量越大,ER表达量越高。3、E_2可能通过ERβ发挥其促进Jurkat细胞凋亡的作用。4、E_2能增加Jurkat细胞中NF-κB的转录活性,Jurkat细胞中NF-κB活性增加有促进凋亡的作用。

Results and ConclusionThe study of time-efficacy relation expresses that after infusing the solution of Phyuanthus emblica Phyllanthus emblica, medicated serum in different time activates the spleen lymphocyte of small mice differently after the 30min but before 180min. During this period, on 2h the activation of the medicated serum is the most obvious. The quantity-efficacy relation research expresses that megadose promotes the propagate of the spleen lymphocyte of small mouse and activates the macrophage in the abdominal cavity more obviously. On the other hand, the small dosage influents the survival rate of the mouse S180 ascites tumor cell more obviously.

结果与结论时效关系研究表明,用余甘子冻干粉溶液灌胃后30~180 min内不同时相含药血清对小鼠脾淋巴细胞具有活化作用,并在给药2 h时实验血清活化作用明显;量效关系研究表明,余甘子大剂量组实验血清对促进小鼠脾淋巴细胞增殖,促进小鼠腹腔巨噬细胞细胞活化作用以及小剂量组实验血清对小鼠S180腹水肿瘤细胞存活率的影响均具显著差异性。

In the exudates from wounds, IL-1 was detected. IL-1 is capable of promoting proliferation of fibroblasts and excretion of collagenase, which induces inflammation and fever and promote wound healing. Inflammation is a defense reaction of the body.

同时,在局部创伤渗出液中测出含有IL-1,而IL-1可促进纤维细胞增殖及促进分泌胶原酶,引起炎症和发热,促进创面愈合,而炎症反应被认为是机体的防御反应,因此MEBO具有抗感染、止痛、促进创面愈合和减轻瘢痕形成等作用。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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