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AMELX, AMBN and ENAM are the major matrix proteins of enamel, and play different roles during different developing stages of tooth germs. AMELX may facilitate the growth of crystals in the early mineral stage, and act in the repairing of bone. AMBN may promote the mineralization of enamel matrix, and also keep the shape and size of crystals. ENAM may act in remineralization and promoting the growth of crystals.

AMELX、AMBN和ENAM为主要的釉质基质蛋白,在牙胚发育的不同阶段有不同的调节矿化的作用,AMELX在釉质矿化早期促进晶体生长,而其在骨中的表达则进一步表明其在骨修复中可能的作用;AMBN促进釉质基质矿化,并维持晶体形状、大小;ENAM促进和维持晶体生长,并与再矿化有关。

Therefore,foliar spraying ofboron was the main measure during flowering period so as to stimulate thegermination and growth of pollen tube,regulate endogenous hormone balance ofovary and promote gynospore formation and,during the phase of young embryodevelopment,spraying of relevant plant growth regulators and potassiumsupplement were essential to stimulating the increasing of endogenous GA1/3 andiPAs,raising the key nutritious substance content in ovary and promoting youngembryo development.

因而花期调节以喷B为主,以便促进花粉管萌发生长,调节子房内源激素平衡,促进大孢子形成;幼胚发育期以植物生长调节剂喷布和K素补充为主,以便启动子房内源GA1/3、iPAS等上升,增加还原糖、淀粉、蛋白质积累和K素吸收,促进幼胚发育。

PartⅡThe mechanism elucidation about effects ofα-(2,3)/(2,6)sialic acid on the Cx43gap-junction functions.(1) Westernblotting experiment showed that the decrease of sialic acid didn\'t changethe Cx43 expression and its phospholation level.(2) Westernblotting experiment showed sialidase didn,t change the ZO-1 expression,IP and confocal experiment showed sialidase improved the interaction of Cx43 andZO-1.(3) Westernblotting experiment showed sialidase didn\'t change N-cadherin expression,IP and confocal experiment showed sialidase promoted the complex formation ofCx43 and N-Cadherin.(4)Sialidase could increase the ERK1/2 phospholation level,and enchanedintercellular homotypic adhesion,Immunofluorometric assay showed sialidase couldpromote the N-cadherin cluster on the membrance.

第二部分:α—(2,3)/(2,6)唾液酸对肿瘤细胞CX43间隙连接功能影响的机制研究1、Westernblotting结果表明降低细胞膜表面唾液酸并不改变Cx43的表达及其磷酸化水平:但Cx43连接斑形成增多;2、Westernblotting结果表明唾液酸酶作用后细胞ZO—1表达没有改变,IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与ZO-1的结合;3、Westernblotting结果表明唾液酸酶作用后细胞N-cadherin表达没有改变,IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与N-Cadherin复合物的形成;4、唾液酸酶作用后细胞内ERK1/2磷酸化水平明显增加,细胞间同质粘附增加,以及免疫荧光表明唾液酸降低后可促进N-cadherin的膜成簇。

The 1000-grain weight heterosis was mainly due to the grain fresh weight heterosis at 12 DPA and 22 DPA that the intervarietal hybrid had, and also due to its promotion of 2 kinds of hormone IAA and CTK 12 DPA, the IAA function extended to 22 DPA.

品种间杂种也具有一定的千粒重杂种优势,这与12天、22天籽粒的鲜重优势有关,籽粒发育早期(12天)2种促进型激素IAA和CTK促进籽粒生长,与其获得较大的鲜重优势有关,IAA的促进作用可延伸到22天。

The amount of Ca8-P in soil with CRMP treatments was lower than that of CMP treatments. The changes of the amount of Al-P, O-P, Fe-P and Ca10-P in soil were neglectable during the course of experiment.3. The shoot and root weight of sorghum increased through application of phosphorus, in addition, The increase of sorghum shoot and root weight was greater than that of common monoammonium phosphate due to the slow release of nutrients from CRMP. The accumulative uptake of phosphorus in shoot and root with CRMP treatment was greater than that with CMP treatment in low (75 mg P2O5/kg soil ) and high(150mg P2O5/kg soil)rates, especially on middle stage, and in high phosphorus rate, this advantage was more obvious than that in low phosphorus rate.

磷肥的施入,促进了高粱地上部和根部的生长,而控释肥由于缓慢释放养分,与作物吸收相一致,更能促进高粱的地上部和根部干物质积累;对于高粱地上部及根部的磷素累积,在两种施磷水平下控释处理地上部及根部磷素累积量均大于非控释处理,尤其是在中期,而且高磷水平下优势更加明显,低磷控释处理的磷素累积量能达到高磷非控释的累积量,即减少一半的用量即能达到同样的效果;在氮、钾、钙、镁相同的水平下,控释处理比非控释处理更能促进地上部及根部氮、钾、钙、镁累积量,这种优势在中期表现最明显。4。

The Anthraquinone element in Morinda officinalis How aids in the proliferation of BMSCs regardless of the polarity of the compound. Though the other compounds of Morinda officinalis How has a certain impact on the proliferation of BMSCs as well, it is of no statistical values. However, the result will be better for the Anthraquinone in Butyl alcohol as the polarity is wider.

巴戟天中的蒽醌苷类成分对促进BMSCs的增殖有效,而其他成分对促进BMSCs的增殖有一定的影响,但无统计学意义;且巴戟天蒽醌苷类成分无论极性大小,对促进BMSCs的增殖都有效,而正丁醇中极性较大的蒽醌苷类成分效果更好一些。

Results When the culture medium was supplemented with 0 .05μg/ml sodium selenite,the proliferation of transformed cells was significant ly promoted and the transformation did not change remarkably,when supplemented w ith 0.25μg/ml,the proliferation was promoted but the transformation was inh ibited,and when with 0.75μg/ml and 1.50μg/ml,the proliferation was not pro moted and the transformation was strongly inhibited.Big dose of (1.50μg/ml) sodium selenite m ade the nuclei of the untransformed lymphocytes gather together like a few grape s doing,and even caused them to fuse.

结果 在培养物中添加0.05μg/ml亚硒酸钠能显著促进转化细胞增殖;添加0.25μg/ml可促进转化细胞增殖,但显著抑制细胞转化;添加0.75μg/ml和1.50μg/ml,不仅不能促进细胞增殖,而且强烈抑制细胞转化。1.50μg/ml剂量的亚硒酸钠使非转化淋巴细胞发生葡萄状聚集甚至核融合。

Trends of overground physiological and biochemical indexs are almost the same—weak soil Naphthalin pollution stress stimulate them,strong pollution restrain stress them. In the first two weeks of seeding stage weak soil Naphthalin pollution stimulate root activity,but soil Naphthalin pollution stress restrain root activity from the second week till jointing stage, In corn grouting stage soil Naphthalin pollution stress stimulate root activity.

部分的生理生化指标都有促进作用,而高浓度的土壤萘污染胁迫对玉米地上部分的生理生化指标有抑制作用;苗期的前两周低浓度土壤萘污染胁迫对玉米的根系活力有促进作用,苗期第三周到拔节期土壤萘污染胁迫抑制玉米的根系活力,而到了用营养生长到以生殖生长为中心的灌浆期土壤萘污染对玉米的根系活力有促进作用。

The expression of HIF-1α protein was positively correlated to MVD, lymph node metastasis and perineural invasion, but not with clinical TNM stage.

结论HIF-1α对肿瘤的新血管生成有促进作用,并可促进肿瘤浸润和转移,从而促进肿瘤的恶性进展。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变,则将导致关节软骨基质成分的丢失和进行性破坏;软骨细胞凋亡与OA的发病密切相关,Fas与NO可各自独立介导软骨细胞凋亡,造成关节软骨破坏;IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子,具有促进细胞生长、增殖与合成等作用,可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用,可促进软骨细胞增殖、分化与蛋白多糖的合成,具有较强的诱导软骨形成的能力,研究表明多种生长因子相互促进、相互抑制,以协同或拮抗方式影响软骨细胞代谢,影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

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