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The PKC family is subdivided into three groups; the classical PKC members are Ca〓 and diacylglycerol dependent, the novel PKCn are Ca〓-independent but diacylglycerol dependent and the atypical PKCs are not activated by Ca〓and diacylglycerol in vitro.

丝裂素活化蛋白激酶是一族在脊椎类动物体内广泛存在的蛋白质丝氨酸/苏氨酸激酶,是目前发现的最主要的一个生长信号调节蛋白,是细胞内多种促细胞增殖信息传递的共同通路或称会聚点,是细胞表型变化和增殖的蛋白激酶。

Nerve stem cell can be differentiation into astroblast, oligodendrocyte and nerve cell induced by factors.

神经干细胞的增殖分化可受各种因素的影响,目前已知,许多细胞因子,生长因子,营养因子以及细胞外环境等因素的作用,可诱导神经干细胞向不同的终末细胞分化,若能在体外分离培养神经干细胞并在促分化因子的作用下,诱导神经干细胞向某一特定方向分化,将为干细胞的分化机制提供有力的实验依据。

Angiogenesis is regulated by signals derived from receptors for both growth factors and ECM molecules. Recent studies have shown that activation of ERKs is closely involved in the migration or tubular-like formation of endothelial cells and induced by various angiogenic factors.

血管新生可以受到许多来自於生长因子受器及胞外基质受器的讯息所调控,而近年的研究也显示ERK的活化不但会受到许多促血管新生因子的诱导,而且跟内皮细胞的移型及管状形成作用有很大的关系。

The effect of AA on BEL-7402 was not significant; However, AA could effectively enhance AT-induced hepatocarcinoma cell apoptosis and lesion severity through activation of caspase-3 but not ERKs-Conclusion; Caspase-3 and ERKs proteins could involve in arsenic-induced hepatocarcinoma cell apoptosis and differentiation respectively as intracellular signaling molecules; The effect between AT and AA on hepatocarcinoma is synergistic, which further inhibits cell growth and induces apoptosis in human hepatocarcinoma cells through activation of caspase-3 but not ERRs.

AA对BEL-7402无明显的作用,但能有效的通过caspase-3而不是ERKs的激活促进AT对肝癌细胞的凋亡效应。结论:ERKs和caspse-3信号蛋白可能分别参与了砷剂诱导的人肝癌细胞促分化和凋亡效应,AT和AA对肝癌细胞的作用有协同性,他们通过caaspase-3而不是ERKs的激活进一步抑制了肝癌的生长,诱导其凋亡。

Malolactic fermentation is a very important processing technology for deacidificaton in modern winemaking.

苹果酸乳酸发酵是现代葡萄酒酿造工艺中重要的生物降酸手段。MLF是L 苹果酸在乳酸菌的苹果酸乳酸酶催化下转变成L 乳酸的酶促反应过程,该过程没有底物水平的磷酸化,但在MLF过程中苹果酸确实能够刺激细菌的比生长速率,增加细菌生物量。

Statistical data of VEGF grading scores showed that its expression was not significantly related to the size and location of glioma, sex, and age of patients, but closely related to the glioma gradings. The expression of TF was positively correlated with that of VEGF, suggesting that TF might participate in the anigogenesis of gliomas, and provide proper environment for the growth of gliomas through its coagulant effect.

根据VEGF分级计数统计学分析,显示VEGF表达与肿瘤的大小、部位及患者性别、发病年龄等临床因素无显著相关性,而与肿瘤的组织学分级密切相关。3、胶质细胞瘤中TF与VEGF的表达正相关,TF可能参与了肿瘤血管的生成过程,并通过其促凝血活性作用为胶质瘤的生长创造适宜的内环境。

And the open sex demand that expends a choice to consuming the increasingly sensitive, offset of the price, durative attention to product quality, closing to hairnet sth resembling a net shops to grow of zoology quickly.

而对消费价格的日益敏感、对消费选择的开放性需求、对产品品质的持续性关注,正促发网络购物生态的快速生长。

"Any circumstance that affects the amount of available insulin-like growth factor so as to modify the sensitivity of the ovary to follicle-stimulating hormone appears to govern the rate of spontaneous twinning," said Dr. Steinman.

&任何能够影响可利用类胰岛素生长因子量的环境因素都可以改变卵巢对促卵胞生成激素的敏感性,进而控制自发性孪生的发生率,& Steinman博士说。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。