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The control group received same volume of normal saline instead. The platelet, prothrombin time, activated partial thromboplastin time, fibrinogen, factor Ⅷ coagulator activity, the operation duration, and blood loss within postoperative 24 h were determined and compared between 2 groups.

测定两组用药前和术后的血小板计数、凝血酶原时间、部分凝血活酶时间、纤维蛋白原定量、第八因子促凝活性;记录手术时间和手术开始至24 h中出血量,评价其临床效果。

Carboxypeptidase inhibitor from potato , a special inhibitor of TAFIa, was used to test effect of heparin and hirudin on activation of TAFI.

对尿激酶诱导的纤溶,水蛭素比肝素有更好的间接促纤溶作用,其原因主要是水蛭素能有效抑制再次血凝的发生,减少了尿激酶和纤溶酶原的短暂性耗竭。

The in vitro anticoagulation activity of the sample was evaluated by activated partial thromboplastin time, prothrombin time and thrombin time.

采用部分凝血活酶时间、凝血酶原时间和凝血酶时间对其体外抗凝血活性作了初步的评价,发现制备的大孔氮化碳对血液不会造成促凝,说明其可能成为一种新的血液相容性材料。

Factor XI deficiency is a rare inherited coagulation disorderassociated with prolonged activated partial thromboplastin time.

XI 因子缺乏是一种与激活部分促凝血酶原激酶时间延长有关的罕见的遗产性凝血功能紊乱性疾病。

CD62p reexpression rate induced by thrombin was 50.88% and PAC1 reexpression was 54.55%. It is concluded that the ability of recovered lyophilized platelets added with reversible activationinhibitors, DMSO and trehalose to aggregate and coagulate has showed no significant difference as compared with FPRP. The reversible activationinhibitors can decrease CD62p expression of lyophilized platelets, and may enhance their survival ability and prolongate survival time. Therefore the efficiency of lyophilizing platelets can be improved based on this freezedrying procedure.

添加血小板可逆性激活抑制剂,海藻糖和DMSO后的冻干血小板,其聚集活性和促凝血功能与新鲜血小板无明显差异,血小板可逆性激活抑制剂降低了冻干血小板的CD62p表达,增强了冻干血小板的生存能力,因而延长了其生存时间,因此可以该冻干方法为基础进一步提高冻干保存血小板的效率。

Statistical data of VEGF grading scores showed that its expression was not significantly related to the size and location of glioma, sex, and age of patients, but closely related to the glioma gradings. The expression of TF was positively correlated with that of VEGF, suggesting that TF might participate in the anigogenesis of gliomas, and provide proper environment for the growth of gliomas through its coagulant effect.

根据VEGF分级计数统计学分析,显示VEGF表达与肿瘤的大小、部位及患者性别、发病年龄等临床因素无显著相关性,而与肿瘤的组织学分级密切相关。3、胶质细胞瘤中TF与VEGF的表达正相关,TF可能参与了肿瘤血管的生成过程,并通过其促凝血活性作用为胶质瘤的生长创造适宜的内环境。

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