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Methods Chicken embryo allantois membrane was used in the experiment. Breast cancer cells were inoculated on the superior surface of CAM sac, then the vascular tissues were collected in lower sac after incubation.

通过鸡胚尿囊绒膜实验和骨条黏附实验确定BSP的高稳定表达对乳腺癌细胞血管侵袭能力及骨条黏附能力的影响。

Giant cell tumor of bone is a kind of common bone tumor,which has characteristics of high recurrence rate and invasion.recently,tumor vessel angiogenesis has been the warm spot of research.genesis,development and metabasis of solid tumor have close relationship with tumor vessel angiogenesis; extracellular matrix degradation is the key point for tumorous infiltration and metabasis;the significant biology characteristic of tumor cell is the disorder of tumor cell differentiation and apoptosis.the correlated research has very important significance for judging gct prognosis and guiding therapy.

骨巨细胞瘤(giant cell tumor of bone,gct)是一种常见骨肿瘤,由于其高复发率和强侵袭性,备受临床骨科工作者的关注。骨巨细胞瘤血管生成是近年来研究热点,实体瘤的发生、发展及转移与肿瘤的血管生成密切相关;细胞外基质降解在肿瘤的浸润和转移中起到关键作用;肿瘤细胞的分化凋亡障碍与无限增殖能力是肿瘤细胞的重要生物学特征。骨巨细胞瘤生物大分子研究的不断深化对判断gct的预后及指导治疗有重要意义。

Objective: To investigate the expression of integrin α4 in osteosarcoma and significance.

目的研究骨肉瘤组织中integrin α4的表达情况,探讨它与骨肉瘤恶性度、侵袭性的关系及临床意义。

Transwellchamber methodand scarification was used to evaluate influence of BSP expression on osteosarcoma cell invasion and metastasis.

以重组基底膜侵袭实验和划痕实验测定对骨肉瘤细胞侵袭力的影响。

Giant cell tumor of bone is a kind of common bone tumor,which has characteristics of high recurrence rate and invasion.Recently,tumor vessel angiogenesis has been the warm spot of research.

骨巨细胞瘤(giant cell tumor of bone,GCT)是一种常见骨肿瘤,由于其高复发率和强侵袭性,备受临床骨科工作者的关注。

In vivo three-dimensional knee kinematics using a biplanar image-matching technique.

旋转铰链型人工膝关节置换在胫骨近端侵袭性骨肿瘤治疗中的应用。

On the other hand, Waldron (1966) suggested the former as identical or similar to the latter, and the word"reparative"should be deleted from the designatum since the lesion did not"reconstruct"in the true sense. It is well known that the biologic behavior of the central giant cell lesion varied considerably and their histologic appearances bear little prognostice implications.

它曾被认为是一种反应增生性病变,不具有真性肿瘤的性质,而有些病例则在临床病理上与长骨骨巨细胞瘤存在相当大的重叠,表现出明显的侵袭性,采用保守治疗方法极易复发。

Method]twelve cases with extremities invasion bone tumor were reviewed,including 6 male and 6 female.the average age was 37.1 years old.according to the mri,typeⅰtumor located in metaphysic and growth eccentricity,and was treated with outside tumor osteotomy with reservation of one side as integumentale,the cut line was shape of "匚".type ⅱ tumor was with invasion part articular surface,and was operated with part joint osteotomy with reservation of one side as integumentale,the cut line was shape of"l".type ⅲ was with invasion total joint surface and as integmentale,all tumor segment including joint could be cut,but the shape of cut close to the diaphysis was echelonment.

方法]12例侵袭性骨肿瘤患者男6例,女6例;平均年龄37.1岁。根据mri表现选择不同截骨方法,ⅰ型肿瘤位于干骺端偏心性生长,采用保留一侧皮质骨的肿瘤外截骨,截骨线呈&匚&形。ⅱ型病例肿瘤侵蚀部分关节面,采用保留一侧皮质的部分关节截骨,截骨线呈&l&形。ⅲ型病例肿瘤侵蚀整个关节面和骨皮质,可切除包括关节在内的整个瘤段骨,只是近骨干侧截骨呈阶梯状。

Spinal giant cell tumor of bone is a kind of primary benign bone tumors in the spine. It is rich in blood supply, aggressive, and easily recurring and lung metastasizing.

脊柱骨巨细胞瘤是一种原发于脊柱的良性肿瘤,血运丰富,侵袭性生长,易复发,并可发生肺转移,因此治疗难度大。

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