侵袭素

in order to establish a rapid, sensitive and specific detection method for identification of four kinds of food-borne pathogenic bacteria including salmonellla spp, listeria monocytogenes, staphylococcus aureus and bacillus cereus by using multiplex pcr, according to invasion protein a geneof salmonellla spp, transcriptional regulatory protein gene of listeria monocytogenes, autolysin gene ofstaphylococcus aureus and gyrase b subunit gene of bacillus cereus, four pairs of specific primers were designed for multiplex pcr amplification.

小 摘要：为建立一种利用多重pcr技术检测和鉴定沙门氏菌、单核细胞增生李斯特菌、金黄色葡萄球菌和蜡样芽孢杆菌的方法，根据沙门氏菌侵袭力蛋白a基因、单核细胞增生李斯特菌蛋白转录调控基因、金黄色葡萄球菌自溶素基因、蜡样芽孢杆菌的促旋酶b亚单位基因设计引物，进行多重pcr扩增，并对多重pcr反应体系进行优化。

Methods The clpE-deficient strain was constructed by LFH-PCR and identified by PCR and sequencing. The impact of clpE mutant on the virulence of S. pneumoniae was evaluated in a mouse model. In addition, we also studied the effect of clpE mutant on adherence and invasion of host cells. Real time RT-PCR was used to measure the mRNA expression levels of autolysin A, pneumococcal surface adhesion A, pneumolysin, pneumococcal surface protein A and neuraminidase The clpE gene was replaced completely by erm cassette.

用长臂同源多聚酶链式反应方法失活clpE基因，用PCR、测序鉴定缺失菌株，通过动物实验观察clpE基因缺失株毒力改变情况，同时用细胞实验比较clpE基因缺失株和野生菌对宿主细胞的粘附和侵袭能力，最后用实时荧光定量PCR分析自溶素(major autolysin A，lytA)、表面黏附素A(pneumococcal surface adhesion A，psaA)、溶血素(pneumolysin，ply)、肺炎球菌表面蛋白A（pneumococcal surface protein A， pspA和神经氨酸酶（neuraminidase， nanA）的表达。

Objective:To study the effect of artemisinin on growth, invasion and metastasis of BGC-823 cancer cell.

目的：研究青蒿素对人胃癌细胞株BGC-823的生长、侵袭和趋化运动能力的影响。

This patient received chemotherapy with DVCP,idarubicin and imatinib mesylate and was treated with sporanox and amphotericin B (Amb; including Amb-L) and cerebrotomy for drainage because the invasive aspergillosis occurred during myelosuppression.

患者在骨髓抑制期发生侵袭性肺、脑曲霉菌感染，给予伊曲康唑、两性霉素等抗真菌治疗，进行了开颅病灶引流术。

Expression of integrin α3 in colon cancer and its relationship with invasion and metastasis.

结肠癌组织中整合素α3的表达与侵袭转移性的关系。

Cutaneous malignant melanoma is one of the most malignant tumors. It is easy for invasion and metastasis.

皮肤恶性黑素瘤是恶性程度较高的肿瘤之一，易于侵袭和转移。

Leptin activates several singal transduction pathways, can regulate ingestion and energy consumption, and enhance cell growth and hemopoiesis .It also can promote cell proliferation and differentiation, and enhance angiogenesis and regulate immunization.

瘦素通过与其受体的结合，活化细胞内多条信号转导通路，在调控摄食和能量消耗，促进细胞生长、造血等方面起重要作用，同时在促进细胞增殖分化、增加细胞侵袭性、促进血管形成和调节机体免疫等方面起作用。

VANILLIN SUPPRESSES IN VITRO INVASION AND IN VIVO METASTASIS OF MOUSE BREAST CANCER CELLS.

最新研究香兰素香兰素抑制体外侵袭和转移的老鼠体内乳腺癌细胞。

Of these, 15 (37%) were in situ melanomas and 26 (63%) inasie melanomas.

在黑素瘤中，15个（37％）是原位黑素瘤，26（63％）个是侵袭性黑素瘤。

Topol L, Jiang X, Choi H, et al. Wnt5a inhibits the canonical Wnt pathway by promoting GSK3 independent catenin degradation ［J］. J Cell Biol, 2003,162:899-908.［2］ Olson DJ, Oshimura M, Otte AP, et al.

Wnt5A基因被认为是评价皮肤黑素瘤侵袭能力的重要指标［10］，并且进一步的研究显示： Wnt5A介导的Wnt/Ca2+信号通路主要通过激活蛋白激酶C增强黑素瘤的侵袭力［11］。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷