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Down-regulated expression of PTEN and up-regulated expression of VEGF〓 were considered as two important events in tumorigenesis of ovarian cancer and could act as molecular markers to indicate the pathobiological behaviors of ovarian cancer. Decreased PTEN expression and increased VEGF〓 expression were closely associated with tumorigenesis and pathobiological behaviors of ovarian endometrioid and serous cancer respectively. Reduced expression of PTEN gene might be involved in carcinogenesis and progression of ovarian cancer by up-regulating the VEGF〓 expression to enhance angiogenesis.

在卵巢癌组织中PTEN基因mRNA表达下调和VEGF〓基因mRNA表达上调是卵巢癌发生的重要分子事件,可作为反映卵巢癌病理生物学行为的指标,且分别与卵巢内膜样癌和浆液性囊腺癌的发生和病理生物学行为关系密切;PTEN基因mRNA表达降低可能通过上调VEGF〓基因mRNA表达促进新生血管形成,进而参与卵巢癌的发生和侵袭

In chronic lymphocytic leukemia there is high frequency of loss of heterozygosity and mutation of atm gene, which related to pathopoiesis and progression of CLL.

慢性淋巴细胞白血病可出现高频率的atm基因杂合性缺失和核苷酸突变,并与其发病及侵袭性病程有关。

enhanced expression of ngf may contribute to the perineural invasion and pain in salivary acc.

acc中ngf表达的增高可能是促进其嗜神经侵袭及疼痛症状发生的原因之一。

Correlation analysis of the results with the extent of perineural invasion, pain and histopathologic characteristics of the tumor was performed.

对胰腺癌病例进行神经侵袭程度评分和疼痛评分,并与NGF表达强度进行相关分析。

When VEGF activity is impaired, tumor cells invade deep into the brain in the perivascular compartment.

当VEGF活性受损时,肿瘤细胞在血管周围腔隙中深入侵袭大脑。

When Shigella flexneri 2a 2457T is cultured at 30℃, it's phenotypically avirulent; when grown at 37℃, its virulence improves greately. There is clear evidence that the temperature-dependent expression of the virulence genes is controlled by H-NS protein.

痢疾杆菌在30℃时不具有侵袭力,37℃时毒力明显增强,已有的研究表明这种依赖于温度的毒力基因的表达受H-NS蛋白的调控。H-NS是一种重要的类核相关蛋白,在革兰氏阴性菌中普遍存在,能够调控大量基因的表达。

May be related to proctitis and a variety of pathogenic microorganisms to the invasion of the intestinal tract.

可能与直肠炎及多种病原微生物对肠道的侵袭有关。

The purpose of this study is to evaluate the proliferative activity of fibroblasts in lung cancer, and to explore its correlation with tumor biologic behavior.

背景与目的肿瘤细胞与间质细胞的相互作用在肿瘤的侵袭和转移中起着重要作用。

Since the original Webway was built of a psychically resistant material which the humans could not replicate, the Emperor used his powers, via the Golden Throne, to protect the human-built section from the Warp.

由于原始的传送网道由一种人类难以仿制的灵力抵抗材料制成,皇帝只能通过黄金王座投射他的力量,以保护人类建造的那一部分网道免受混沌的侵袭

Objective: To study the effects of the enlarged Caldwell-Lu approach under nasal endoscope on the resection of pterygomaxillary fossa tumor.

目的:探讨在鼻内镜下采用扩大的Caldwell-lu进路处理鼻腔及向翼腭窝侵袭肿物的手术方式。

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The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作:对伸臂位于顶部的单层框架—筒体模型进行分析,提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。

Its advantage is that it can be used in smaller units.

其优点在于可以在较小的单位中应用。