侵蚀

The reason of the disease is uncertain and its pathologic change is chronic Inflammation of joints, cell infiltration, information of pannus and the erosion of cartilage and bones, which lead to the destruction and dysfunction of joints structure.

本病病因未明，主要病理变化为关节滑膜的慢性炎症细胞浸润、血管翳形成、软骨及骨组织的侵蚀，导致关节结构的破坏和功能丧失。

Brane, such as synoviocytes, macrophages, osteoclasts and TNF-αvv acts on different kinds of cell in synovial memchondrocytes, which can produce metalloproteinase,collagenase, stromelysin and so on, further induce pannus formation, joint inflammation, bone erosion and cartilage degradation.

TNF-α可作用于RA关节组织中的滑膜细胞、巨噬细胞、软骨细胞和破骨细胞，使这些细胞活化，产生金属蛋白酶、胶原酶、基膜溶解酶等，导致局部炎症反应和血管翳形成，进一步引起软骨破坏和骨侵蚀。

Morning stiffness, symmetric arthritis, RF positivity, ESR, CRP and synovial hyperplasia, enhanced pannus, bone marrow edema and bone erosion have certain differentiating diagnosis value between early RA and non-RA.

以晨僵、对称性关节肿胀、ESR增快、RF阳性、CRP值升高、血管翳强化、滑膜增厚、骨侵蚀、骨髓水肿为指标时对于鉴别早期RA与非RA具有一定诊断价值。

There were significant differences between RA and non-RA groups in morning stiffness, symmetric arthritis, rheumatoid factor positivity, erythrocyte sedimentation rate, C-reactive protein and synovial hyperplasia, enhanced pannus, bone marrow edema as well as bone erosion.

晨僵、对称性关节肿胀、类风湿因子(rheumatoid factor， RF)阳性、血沉(erythrocyte sedimentation rate， ESR)增快、C反应蛋白(C-reactive protein， CRP)值升高诸指标在RA组与非RA组之间具有显著差异性。MRI各主要征象中滑膜增厚、血管翁强化、骨髓水肿、骨侵蚀诸指标RA组与非RA组之间具有显著差异性。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

HPV infection can arouse the cleavage and proliferation of cholesteatoma epithelium and may play certain role in the occurrence and development of middle ear cholesteatoma. Aggressive, papillomatous growth and koilocytes can be served as the initial proof of HPV infection in cholesteatoma of the middle ear.

HPV感染可能激发中耳胆脂瘤上皮的分裂增殖，在中耳胆脂瘤发生发展中起一定的作用；侵蚀性乳头瘤样生长和空晕细胞改变可以作为中耳胆脂瘤组织中HPV感染的病理学证据。

Magnesia alumina spinel brick is based on high-purity magnesia and synthetic magnesia alumina spinel with major crystal phase of periclase and spinel. By intensively mixed, double-face pressed and fired at high temperature. Being completely chrome free, it is the ideal refractory for the transitional zone of cement kiln characterized by superior thermal shock resistance, good anti-erosion capacity, and lower thermal conductivity.

此次展会为您展出的水泥回转窑用镁铝尖晶石砖以高纯镁砂和合成镁铝尖晶石砂为主要原料，主晶相为方镁石和尖晶石，经过强力混练，双面加压，高温烧成等工艺制成，是水泥窑过渡带的标准耐火材料，具有无铬污染，热震稳定性好，耐磨损，抗侵蚀性强，热导率低等特点。

Soil erosion which is called"peristaltic disaster"is one of the most common and the strongest geological disaster in human society nowaday.

土壤侵蚀是当今人类面临的一种最普遍、持续性很强的环境灾害，被称为&蠕动的灾难&。

The author found that the big piece-size muscovites of China are the normal muscovites; the small-size muscovites in the metamorphic rock area are mainly phengite. The Indian muscovites studied both big and small piece-size of muscovite, are normal muscovites. The surface activity of Indian muscovite substrate is higher than China ones. Acid is easy to erode paralleling to the direction of the muscovite substrate face. Although acid treating does not destroy the muscovite structure, the thermal stability of muscovite has be decreased.

研究发现我国白云母主要产地的大片白云母均为普通白云母，变质岩地区的碎白云母以多硅白云母为主；本文研究的印度的大片白云母、碎白云母均为普通白云母；印度白云母基片的表面活性高于我国白云母；酸处理容易沿平行于白云母基面的方向侵蚀，虽未使白云母晶体结构产生破坏，但造成了白云母热稳定性降低。

In Zhejiang,the moun- tain and hill areas make up 70.4% of its total area. Owing to the effect of both physiographical factors(rock character, landform,soil,vegetation and rainfall,etc.)and anthropogenic factors deforestation,land reclamation on steep slops and irrational use of Land resource,etc.

由于自然条件和人为因素的影响，土壤侵蚀严重，致使土地退化，河床、水库淤高，生态环境恶化，水旱灾害加剧，成为浙江省农业生产和国民经济发展的一大制约因素。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。