使降低

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

They must be read by computers or anagogic equipment. They are relative small and light but they can be deposited a vast of information and the information can last long. Multimedia and interactive internet publications can be retrieved conveniently. The information of internet publications can be refreshed, edited, transferred, communicated by Internet quickly, internet publications possess access speeds, retrieval accuracy, interactivity, and flexibility.

网络出版物具有信息量大，使用方便，可对信息进行各种处理，检索快速便捷，图文声像并茂，交互性强，省去了印刷、装订、储运等环节，降低了生产成本，出版周期短，信息通过计算机网络高速传播，信息获取快、传播快、更新快等特性；并且具有计算机检索功能、超文本功能，使之成为一种具有强大生命力的大众文化传播媒体，给人类社会带来了深刻的影响。

On the other hand, she added,"use of hormonal contracepties with a low androgenic progestin was associated with a 16% decreased risk of gestational diabetes."

在另一方面，她又补充道，&而使用含低度雄激素源性孕酮的激素避孕药使妊娠糖尿病风险降低了16%。&

The effects of doping concentration of iodine, doping time, doping temperature and exposure time on volume resistivity of anthracite were studied; and also the effects of solution concentration of cupric chloride, doping time, doping temperature, soking time of cupric chloride and exposure time on the volume resistivity were studied; Anthracitic resistivity has been decreased in dissimilar extent, and furthermore ,volume resistivity stability of the doping anthracite made by liquid phase doping method is more better than gas phase mothed; Resistivity and its stability were better than the doping method of iodine in fused salt doping method of cupric chloride.

研究了I_2掺杂浓度、掺杂时间、掺杂温度和暴空时间对无烟煤电阻率的影响；探讨了CuCl_2溶液的浓度、掺杂时间、掺杂温度和CuCl_2溶液浸泡放置时间以及暴空时间对无烟煤电阻率的影响：结果发现：I_2气相掺杂和液相掺杂均使无烟煤的电阻率有不同程度的降低，而液相掺杂法所得材料的电阻率稳定性更高；CuCl_2熔盐掺杂法所得材料的电阻率及其稳定性均优于I_2掺杂法。

The result showed that the activity of photoreduction,photophosphorylation and SOD in chloroplasts increased when reactionmedium added calcium with concentration of 0.04mmol/L,lessened theaccumination of free radical and the destruction of membrane system,which manifested the indirectly antiacid function.

酸雨胁迫降低龙眼的坐果率，并且坐果率随酸雨pH的下降而下降，同时使单果重、TSS、固酸比和糖酸比下降。pH3.5处理的K+、Ca2+、Mg2+和可溶性糖的渗出量与对照差异达极显著水平，说明已对果实品质造成影响。

Glucose has obvious protection from the hot stability of the deer placenta polypeptide, The denaturation rate of the deer placenta polypeptide reduces 40.11%, the antioxygenic property enhances 34.19% when it is heated under 60℃ for 30min with glucose's joining.

葡萄糖对鹿胎盘多肽的热稳定性有明显的保护作用，它使鹿胎盘多肽在60℃的条件下加热30min 后的变性率降低了40.11%，抗氧化性提高了34.19%。

Thus, it is reasonable to speculate that impairment of lung tissues resulting from the imbalance between protease and antiprotease system due to α〓AD may be predisposed to the development of lung cancer, and may also be related to the susceptibility to lung cancer.

AT活性降低使个体发展为肺癌的危险性增加。我们有理由推测由于α〓AT缺乏导致的弹性蛋白酶/抗弹性蛋白酶平衡系统的失衡，进而产生的肺组织损伤可能是肺癌发生的前期病变和重要基础。

To further reduce smoking in New York City, in 2006 the New York City Department of Health and Mental Hygiene began an extensive, television-based antitobacco media campaign using graphic imagery of the health effects of smoking, which aired simultaneously with a large New York state antitobacco media campaign.

为使纽约市吸菸率降低的成效更佳，纽约市健康暨心理卫生局（Department of Health and Mental Hygiene，以下缩写为DOHMH）於2006年开始一个广泛性、以电视宣传为主的反菸媒体运动，其中采用吸菸所造成之健康影响的图像，该运动和一个大型的纽约州反菸媒体运动同时播出。

Based on field experiment and measure data, ecological characteristics of soil water in different fencing sandy land in arid desert area and vegetation restoration effect of soil water variation in fencing sandy land were analyzed. In representation of Artemisa arenaria DC population, observing and researching vegetable restoration effect of soil water variation in fencing sandy land. The results indicate as follow:(1)With the vegetation development constantly in fencing sandy land, soil water utilization of vegetation increased. It made soil water content and soil water storage reduced with the increase of fencing time in sandy land.

本文通过野外实验测定数据，分析研究了干旱荒漠区不同类型封育沙地土壤水分生态特征，以及封育沙地土壤水分变化对植被恢复的影响，并以当地沙蒿种群为代表，观测研究封育沙地土壤水分变化对植被恢复的影响，结果表明：(1)封育沙地随着植被的不断生长，植被对土壤水分的利用也有所增加，从而使沙地土壤含水量和储水量随封育时间的加长而表现为一定的降低趋势。

The production technology was optimized and the quality standard was improved in this study, making the products quality controllable and assurable,and reducing the production cost meanwile.The study was significative to make the most of peanut hulls resource and promote the peoples health cause.

通过本研究，首次制定了脉舒胶囊的含量测定方法及其限度，提高了产品质量标准，并且优化了生产工艺，使制剂质量稳定、可控，同时生产成本可以明显降低，对于充分利用花生壳资源和促进人民群众的健康事业均有积极的意义。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。