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At present there is no effective therapeutics to treat PD except the allopathy. The discovery of neural stem cells in the adult mammalian brain provides a new chance to effect a radical cure on PD. But how to make the limited neural stem cells proliferating enough and differentiating into the dopaminergic neurons which can repair the nigrostriatal pathway and help to eliminate the PD symptoms becomes an urgent problem.

成年动物脑内神经干细胞的发现为根治帕金森病提供了新的细胞源泉,但如何使有限的神经干细胞增殖到足够数量并转化为多巴胺能神经元,使之能够修复黑质纹状体通路,逆转帕金森病临床症状,是目前亟待解决的问题。

We have gone from a world where energy is plentiful and cheap to one where it is scarce and expensive, and I don't see what will change to flip that back again, he said.

我们已从能源丰富而廉价的世界来到了能源稀缺而昂贵的世界,而且我认为,没有什么变化能使这一潮流发生逆转。

You can crossfade, backspin, speed up and slow down music, including full-length WAVE and MP3 songs.

你能够交替淡变,逆转,加速和使音乐慢下来,包括全长的 WAVE 和 MP3 歌曲。

Results The recombinant retrovirus resulted in the number reduction of GFAP positive cells around the injured sites. The typical characteristics of reactive gliosis disappeared. The formation of the glial cicatrix was inhibited.

结果 重组反义GFAP逆转录病毒使脑穿刺损伤灶周围GFAP阳性细胞数量明显减少,反应性胶质化的典型特征消失,胶质瘢痕形成明显减少。

These changes were abolished in 2K1C rats treated with captopril. L-arginine partially reversed the change of aortic contractibility of 2K1C rats, and elevated aortic cGMP content.

卡托普利可逆转2K1C大鼠的上述改变。L-精氨酸可使上述异常的主动脉收缩功能部分恢复,并增加主动脉cGMP含量。

While it would be unimaginable for Chelsea to drub Roma 7-1, there is little to indicate that United have the resilience to win at Valencia. Despite the fact that tonight's meeting will not see either team at full strength, the respective philosophies should still be visible.4 b/ Q$ U3 A' m

如果是切尔西7:1屠宰罗马,你估计很难相信,当然如果换成曼联客场挑战瓦伦西亚的话,逆转获胜可能性也很小,不论今晚(注:指昨晚切尔西与曼联的联赛比赛)双方的较量会不会使出100%的力气,两队仍会展示各自不同的踢球风格。0 R+ a: C$ C t O4 r' X8 b; m

Blocking tonic GABAA receptors with the additionof 100 M picrotoxin produced an additional 40% reversalof the thiopental-induced depression, but no additional reversalwas seen for isoflurane-depressed responses.

再添加100M印防己毒素阻断持续性GABAA受体可使硫喷妥产生的抑制再多逆转40%,但对异氟烷产生的抑制没有进一步的逆转作用。

Thunberg Fritillary Bulb is one of the most popular Traditional Chinese herbs. Some trials in vivo and animals indicated that Peimine and Peiminine, extracted from Thunbery Fritillary Bulb, have the function of reversing MDR of two different kinds of mechanisms. They can improve the cytotoxic of ADR to cancer cells by 5~10 folds under concentration of 10% cancer cell growth inhibitory rate. Peimine and Peiminine not only feather typical character of modifier of MDR, but also differ from other moldifiers such as Calcium channel blocker, Cyclosporines in chemical structure, they belong to cevine groups alkaloid, a subgroup of C-Nor-D-homosteroid alkaloid.

浙贝母是临床常用中药,体外及动物试验证明,浙贝母中的有效活性成分贝母甲素和贝母乙素具有逆转肿瘤细胞MDR的作用,而且能逆转两种不同机制的多药耐药肿瘤细胞的耐药性,在无明显细胞毒剂量下,可使阿霉素对耐药肿瘤细胞的杀伤活性提高5-10倍,不但具备明确的多药耐药逆转剂的特征,而且在化学结构上属异甾类生物碱中的瑟文类生物碱,完全不同于钙离子拮抗剂、免疫抑制剂和其它现有的耐药逆转剂,具有作用靶点宽、化学结构独特的特点。

HTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site.

人端粒酶逆转录酶是一种核糖核蛋白酶,由端粒RNA和端粒酶蛋白组成的一种特殊逆转录酶,在激活端粒酶的过程中起限速作用,能以自身RNA为模板合成端粒序列以稳定端粒长度使细胞获得永生,也是人类端粒酶的活性中心,其表达是端粒酶活化的必须前题[2~4]。

Also the multi-scale entropy processing and analysis of conductance fluctuating signals acquired by VMEA sensor for five flow patterns with water as the continuous liquid are conducted. The study result indicates that the increase of f o makes oil in water type slug flow occur at lower U sg; for low flow velocity, the continuous liquid inversion occurs at about f o=0.9 and the increase of U sg makes the inversion point move to low oil volume fraction; the multi-scale entropy detail describes the nonlinear dynamic characteristics of oil-gas-water flow patterns and the rate of MSE at low scales sensitively indicates the variation of flow patterns and can act as the efficient criterion of three-phase flow patterns identification.

对水为连续相的5种流型VMEA传感器波动信号进行了多尺度熵分析,研究结果表明:含油率增加可使水包油段塞流在较低气相表观速度下产生;较低流速下的油水相态逆转可发生在油液比为0.9左右,气相流速增加使得逆转点向含油率低的方向偏移;多尺度熵细节可以刻画油气水三相流非线性动力学特性,而低尺度的多尺度熵变化率敏感地反映流型转变,是划分油气水三相流流型的有效准则。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。