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Sanchez ET ,Botella LM ,Velasco B ,et al. Synergistic cooperation between hypoxia and transforming growth factor2beta pathways on humanvascular endothelial growth factor gene expression. J Biol Chem ,2001,19,276:38527238535.[3] Blancher C,Moore JW,Talks kl,et al.Relationship of hyposia-inducible factor HIF-1alpha expression to vascular endothelial growth factor I nduction and hypoxia survival in human breast cancer cell lines.

肝细胞癌中缺氧诱导因子-1α、热休克蛋白70的表达】;综上所述,肝细胞癌发生后,由于血供不足诱导HIF-1α过度表达,应激状态下产生的HSP70通过减轻缺血性损伤,增加毛细血管的生成及减轻细胞凋亡等途径使肿瘤细胞的增殖、移行加快,促进恶性肿瘤的生长、浸润和转移,使肿瘤细胞在适应缺氧、能量代谢、细胞凋亡及转移中起重要作用。

Dosage is not to had been jumped over more more when using, must right amount, because cassia bark, clove, fennel, ginger and peppery wait makings, although they belong to natural dressing, but if dosage is excessive, the secondary action with be had particular likewise and even noxiousness and lure denaturation, when be being used so, answer with " peace is little not much " advisable.

使用时并非用量越多越好,一定要适量,因为桂皮。丁香。茴香。生姜以及胡椒等料,它们虽然属于天然调味品,但假如用量过度,同样具有一定的副作用乃至毒性和诱变性,所以使用时应以"宁少勿多"为宜。

The blood pressure of.1 of pathology physiology mechanism that SAS causes CVD breathes time-out to be able to bring about airframe in elevatory Morpheus anoxic, sympathetic is excessive and excited, element of serous catechu phenolic amine, kidney and hemal endodermis element are elevatory, bring about hemal easy of hemal convulsion; to shrink the function is disorder, can make blood-vessel flowing flesh happening reframes and fleshy, systemic blood-vessel obstruction adds element of the kidney when; is chronic and anoxic, system of hemal and nervous element is activationed, bring about blood pressure to lift. Obstruction of way of energy of life of patient of OSAS of disease of blood of 1.2 low oxygen increases, cause air current to interrupt, breath pauses, at the same time airframe gets used to low oxygen environment gradually, breathing centre drops to low oxygen and sensitivity of disease of blood of tall carbonic acid, breath suspends a frequency increasing, farther aggravating airframe is anoxic. 1.3 heads are self-adjusting the function drops normal person changes quickly in systematic circulation blood pressure when, the head can be passed adjust independently functional generation protects effect, make change of cerebral blood flow not big.

SAS诱发CVD的病理生理机制。1血压升高睡眠中呼吸暂停可导致机体缺氧,交感神经过度兴奋,血浆儿茶酚胺、肾素以及血管内皮素升高,导致血管痉挛;血管舒缩功能紊乱,可使血管平滑肌发生重构和肥厚,全身血管阻力增加;慢性缺氧时肾素—血管紧张素系统被激活,导致血压升高。1.2低氧血症OSAS患者气道阻力增加,造成气流中断、呼吸暂停,同时机体逐渐适应低氧环境,呼吸中枢对低氧和高碳酸血症敏感性下降,呼吸暂停次数增加,进一步加重机体缺氧。1.3脑自动调节功能下降正常人在体循环血压快速变化时,脑可通过自主调节功能产生保护效应,使脑血流量变化不大。

It transforms the image based on the cumulative distribution function of histogram. However, there is a caveat to over-enhance the contrast when the auto-generated transform curve is too sharp due to some high peaks in the histogram.

但是当直方图的分布函数中某一个值特别大的时候,则会使产生的转换函数斜率过大,换句话说就是使影像过度增强,这会使输出影像太亮,清晰度反而下降。

However, the same nerve stimulation caused a reverse in renal nerve discharge when the central sympathetic activity was inhibited by hyperventilation or unilateral depressor nerve stimulation.

相反,用过度通气或刺激一侧降压神经的方法使交感中枢活动水平降低时,同样的参数刺激排深神经,则使肾神经发放增加。

A classic example of an intentional imperfect exposure is when a photographer intentionally overexposes a portrait of an older woman by a full f-stop or more to minimize facial lines and wrinkles. While the exposure is intentionally imperfect, it complements the subject and provides a pleasing image.

比如,这里有一个刻意使曝光不完美的典型例子:一个摄影师刻意将光圈数调到最满或更多来使一张老妇人的图片上显现最少量的线条和皱纹,使其曝光过度,这种曝光设置是不完美的,但它赞美了被摄体,并且达到了很好的视觉效果。

Result 1. CDK4, P16 were expressed in parabasal layers and the upper layer, mainly in the prickle and granular layers of cholesteatoma epithelium. Their positive rates were 68.6% and 88.6% respectively. Statistical analysis showed that there was a significant difference in positive rates between

CDK4与P16在中耳胆脂瘤上皮中均过度表达且有一定程度的正相关性,表明它们在疾病发生中是共同而非单独起作用的,从细胞周期的角度可反映胆脂瘤上皮细胞过度增殖的同时也增强负调控因子来抑制增殖,使凋亡同时加快而达到新的平

The precondition and principal part of option and option trade in electricity market is expatiated in this paper,the classification and relationship among those option trades are declaimed,the applications of option tools in electricity market is also enumerated.How ...

价格的过度波动容易造成市场的不稳定及系统运行安全的隐患,如何使整个电力市场的运行建立在长期价格信号和理性交易之上,避免因市场参与者的盲目和短期行为造成电力价格过度波动,已经

Based on those analyses and conformed international and national economic condition in china and some intrinsic defects of target zone regime, author transform target zone exchange rate regime by dividing two layers and bring forward a new exchange rate regime: double-layer-monitor exchange rate regime, the new model have possessed two merits, one is that the new model make "hollymoon effect" of target zone recurrence,and the merit can alleviate the fluctuation of exchange market;another merit is that the new model is a self-regulation system, that is say, the model can avoid long-term misalignment of exchange rate, those merit have major significance for china economy sustainable development and Chinese financial system more perfection, in paper we also present some fiscal policy and money policy served as a foil to double-layer-monitor exchange rate regime in order to make it work well, at last, we conclude that the new model will be the prior selection of RMB exchange rate regime reform for a long time form now on, and it also can serve as the bridge of RMB exchange rate regime steering to one of bipolar—free float.

在这些分析的基础上,并考虑到当前中国所面临的国际国内经济环境,针对汇率目标区的一些固有缺陷,笔者又对汇率目标区模型进行了分层改造,提出了一个新的汇率机制模型:汇率目标区双层监控模型,该模型有两个主要优势,一是可以使&蜜月效应&得以重现,从而避免外汇市场的过度波动;二是该模型是一个自稳定系统,能够进行自我调整,使实际汇率同长期均衡汇率保持一致,从而避免实际汇率的长期错位。这些优点对于我国经济的可持续发展,对于我国金融的更加完善,有着十分重要的意义。为使汇率目标区双层监控模型良好运行,论文还就相应配套的财政政策、货币政策措施作了探讨。最后得出结论,按照汇率制度&并存继起&假说,今后很长一段时间内,汇率目标区双层监控模型都将是人民币汇率制度的合意选择,另外,它也可作为人民币汇率制度向独立浮动制过渡的桥梁。

In the Financial Times last week, the economist Richard Layard argued that too much individualism and too much greed had brought us to this and we need to bring back the good old days of values and trust and altruism.

经济学家理查德·莱亚德上周在英国《金融时报》撰文表示,过度的个人主义和过度的贪婪,使我们落到了这个地步;我们必须重拾昔日美好时光的价值标准、互信和利他主义。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?