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If the antitumour efficacy of these epigenetic drugs is eentually demonstrated, they would not only be added to the current anticancer armamentarium, but they will surely be affordable to the ast majority of cancer patients liing in low and middle income countries, who find the newer anticancer agents prohibitiely expensie.

如果这些表观遗传药物抗肿瘤的作用最终得到证实,他们不仅仅增加了当前抗癌的物质,而且他们可以明确的可以使在发现新的抗肿瘤剂相当昂贵的国家收入在中下等的大量肿瘤患者负担的起。

If we do not do these things, we will be left with two unacceptable choices–(1) relegating crippled and brain-damaged victims of medical negligence to monetary recoveries for their life of suffering that would not even pay for one week of salary of an Enron executive or our president's four years at prep school, or (2) allowing insurance companies to reap profits from good and caring doctors and hospitals in such huge sums that these health care providers will no longer be able to afford to render the type of care that the system should seek to obtain.

如果我们没有做这些事情,我们将只剩下两个令人无法接受的选择,( 1 )降级瘫痪和脑损伤的受害者医疗疏忽货币回收率为他们生活的痛苦,甚至不支付一周的工资安然公司执行或我们总统的四年在预备学校,或( 2 )允许保险公司获得良好的利润和照顾的医生和医院在这种巨额资金,这些医疗服务提供者将不再能够负担得起,使类型的护理该系统应设法获得。

All these bear upon him with crushing weight.

这些问题使他的负担极其沉重。

Excessive calcium intake made the viscera coefficient of rats changed, and had certain harm to testicle and kidney and so on. The absorbability and using of calcium were decreased, which wasted calcium and increased metabolizable burden of body. At the same time, it made the concentration of serum zinc and serum iron depressed, but the serum calcium went up.

过量钙喂养使大鼠脏器、器官的脏体系数发生改变,对睾丸、肾脏等器官有一定危害;机体对钙的吸收、利用率下降,造成补钙剂的浪费,增加机体代谢负担,同时使血清铁、锌浓度降低,血清钙浓度增高,尿钙增加,是肾结石的潜在危险因素。

The failure of charge policy on the price of real estate speeds up the rise of house price, aggravates those middle-low income group's shoulder, restrains the development of other industries, results in the unbalance between economy structure and social structure, invites new unjustness on social distribution, contuses the enthusiasm of labours badly, brings profound social problems, and even induces the breakout of finance crisis, presenting a mass of bad debts towards finance organization, all of which make the whole country economy be in hot water.

房地产价格调控政策的失灵,使住房价格上涨过快,加重了中低收入人群的负担,抑制其他产业的发展,导致经济结构和社会结构的失衡,招致社会分配新的不公,严重挫伤劳动者对策积极性,带来了深刻的社会问题,甚至会导致金融危机的爆发,给金融机构带来大量的呆账和坏账,使整个国民经济陷入困境。

Now our system of real estate rent, tax and fees has many problems. On the one hand, the shortage of the rent makes tax not serious and standard and abets the tendency of collecting unconscionable fees; on the other hand, it leads taxpayer to have the excess burden of taxation. The situation which makes tax unfair, decreases tax base and narrows tax revenue, limits the government's macro-management.

目前我国房地产租税费相互错位,一方面地租不到位,使税收失去了严肃性和规范性,滋长了乱收费的不良风气;另一方面,这种情况也导致纳税人负担过重和税负不均,加之产权关系模糊,结果是未达到平均税负、促进公平的目的,反而造成了税基的缩小和税款的流失,使税收的产业调控功能受到很大限制。

Morgan billions of dollars in interest payments and loan fees, it is also likely to save the bank from the costly and lengthy process of foreclosing homes and selling them.

虽然减轻这些按揭贷款的还款负担有可能使摩根大通损失数十亿美元的利息和贷款服务费收入,却也有可能使该公司从耗时破财的申请住房止赎和出售止赎住房中解脱出来。

They also want to cap fees and make them more representative of the costs incurred by the phone company while also prorating the penalties over the course of the contract.

一方面,他们想要设定收费的上限,使其更能代表电话公司所负担的成本,另一方面使各方在合同期内按比例分摊罚金。

Most mortgages in default were issued in 2006 and 2007, when lending standards were loosest and the housing market was peaking.

房价下跌使供房负担变得更可承受,并使许多地区的房价收入比更接近长期趋势水平。

It is a condition precedent to any liability of the Company that the Insured shall see to it that everything is fit for its intended use and shall exercise due diligence in making the premises free from encountering the aforesaid contingencies.

被保险人条必注意使一切物件适合其原定用途,并应克尽职责,使营业处所避免发生上述意外事件,是本公司负担任何赔偿责任的先决条件。本条除上述规定外,其他均以本保险单所载条款为准。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。