使显著

The off-contractions were also cholinergically mediated as they disappeared under non-adrenergic,non-cholinergic conditions using atropine and guanethidine.In fundic strips,ghrelin and GHRP-6 induced on-relaxation and off-contraction and both ghrelin and GHRP-6 may significantly reduced on-response and increased off-response.

在胃底部，Ghrelin和GHRP-6可使on-response诱导的平滑肌舒张活动减弱，off-response诱导的肌条收缩活动增强，且Ghrelin作用明显强于GHRP-6.L-NNA可显著增强Ghrelin和GHRP-6的促平滑肌收缩效应，但L-AA可显著减弱该作用。

The research results showed that the effects of personality characteristics on kinesthesis position accuracy of elbow joints and stability of hand action were not significant,the kinesthesis position accuracy of elbow joints obviously increased by using the rationing motor load, but the stability of hand action did not obviously change.

研究结果表明：个性特征对肘关节动觉方位准确性和手动作稳定性的影响不显著；定量运动负荷可以使肘关节动觉方位准确性明显提高，而手动作稳定性变化不显著。

The results indicated that the concentration of Cu in the soil is 220.16 mgkg^(-1) contrast to the CK 500.31 mgkg^(-1) significantly decrease when the concentration of EDTA in the soil is 2 mmolkg^(-1) that explains EDTA treatment significantly decreased soluble Cu content in soil because of translating into Cu of water distill floating on the surface of soil and most accumulating around root. Contemporary, application of EDTA to the soil significantly enhanced mobilization of Cu in soil and increased Cu uptake in shoot of Leersia hexandra Swartz., the highest concentration in the leaves 336.54 mgkg^(-1) is 4 times higher compared with the ck 80.34 mgkg^(-1). However, citric acid, oxalic acid and malic acid inhibited mobilization of Cu and less significantly affected shoot Cu accumulation.

结果表明，当向土壤中施加质量摩尔浓度为2mmolkg^(-1)的EDTA时，土壤中Cu质量分数为220.16mgkg^(-1)与空白土壤中500.31mgkg^(-1)相比明显减少，说明EDTA可以极显著的降低土壤中的铜质量分数，使其转化成水提取态的Cu浮于土壤表面，并大部分聚集在根部周围，同时向土壤中施加EDTA不但促进了对Cu的活化而且显著提高了李氏禾对Cu的吸收，叶中最高质量分数达到336.54mgkg^(-1)是对照中80.34mgkg^(-1)的四倍；而柠檬酸、草酸和酒石酸则抑制了Cu的活化，但对李氏禾地上部分的Cu质量分数影响不大。

The results show that Re-K-Zn compound modificator has remarkable effects in high Chromium white cast iron when the modificator has 0.5%Re+2.0%K+0.008%Zn. The modificator not only or bar-like carbides but also improved the mechanical properties of high chromium white cast iron,with its impact toughness enhanced from 7.0J/cm2 to 11.7J/cm2 and its hardness enhanced from 54HRC to 57HRC, and the wear resistance increased by 350%.

实验结果表明：Re-K-Zn复合变质剂在高铬白口铸铁中有显著作用，而且当三者的加入量约为0.5%Re+2.0%K+0.008%Zn时，能显著细化组织，使其组织中网状碳化物变为粒状或条状，提高了高铬白口铸铁的力学性能，铸态冲击韧性由原来的7.0J/cm2提高到11.7J/cm2，硬度由原来的54HRC提高到57HRC，相对耐磨性能提高了3.5倍。

Results When the culture medium was supplemented with 0 .05μg/ml sodium selenite,the proliferation of transformed cells was significant ly promoted and the transformation did not change remarkably,when supplemented w ith 0.25μg/ml,the proliferation was promoted but the transformation was inh ibited,and when with 0.75μg/ml and 1.50μg/ml,the proliferation was not pro moted and the transformation was strongly inhibited.Big dose of (1.50μg/ml) sodium selenite m ade the nuclei of the untransformed lymphocytes gather together like a few grape s doing,and even caused them to fuse.

结果 在培养物中添加0.05μg/ml亚硒酸钠能显著促进转化细胞增殖；添加0.25μg/ml可促进转化细胞增殖，但显著抑制细胞转化；添加0.75μg/ml和1.50μg/ml，不仅不能促进细胞增殖，而且强烈抑制细胞转化。1.50μg/ml剂量的亚硒酸钠使非转化淋巴细胞发生葡萄状聚集甚至核融合。

Results: Proliferation of K562 cells was significantly inhibited by naringenin and the IC50 at 24, 48 and 72h were 455, 225 and 175μmol/L respectively. Cell growth inhibition and apoptosis were observed under light microscope and transmission electron microscope. Observation by flow cytometry indicated that K562 cells were blocked in G0/G1 phase of cell cycle in naringenin group, and S phase cells were remarkably decreased. PCNA expression in each treatment group was remarkably less than in control group.

结果：柚皮素对K562细胞增殖有明显抑制作用，作用24，48和72h后的半数抑制浓度(IC50)分别为455，225和175μmol/I；柚皮素处理组细胞在普通光镜和电镜下均见观察到显著的增殖抑制和典型的细胞凋亡形态学改变；流式细胞仪分析证实柚皮素能使K562细胞聚积在G0/Gl期，S期细胞减少；在处理组PCNA的表达显著低于对照组。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th／Ts及Th1／Th2平衡紊乱，抑制大鼠PHφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱，抑制大鼠PMφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

Items of pH, soil solution K, exchangeable k, nonexchangeable K and potassium fixation index were all determined after incubation. The results indicated similar extent and trends of transformation among three K forms, that is, decreasing content of soil solution K and exchangeable K but increasing nonexchangeable K level were observed in both CaCO3 and SrCO3 treatments of two soils. As to CaCl2.2H2O addition, pH increase was not found and the change of three K forms was not significant when application rate raised.

结果显示CaCO3的添加，除能提升土壤pH值外，亦能使土壤中三种型态钾(溶液性钾，交换性钾，非交换性钾)有显著的改变，且改变程度及趋势均甚为相似，而CaCl2.2H2O的添加不会造成土壤pH的改变，且三种型态钾并不随CaCl2.2H2O用量的增加而有显著改变的现象。

Trial group incurred more outpatient costs and Nontrial group incurred more inpatient costs. Patients' median survival, receiving second line chemotherapy treatment, radiotherapy, surgery, patients with heart disease and those who received free drug while participating in clinical trials were all significant predictors of treatment costs.

分析影响病患医疗费用的因子，较长的存活时间、接受第二线以上化疗、接受放疗、接受手术、有心脏疾病等因子会显著增加费用，而参与由厂商提供免费新药的试验则会显著的使医疗费用减少。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务，你就做你的事好了。