使显著

Viral vector mainly contain adenovirus, retrovirus,adeno-associated virus and so on, but it has potential danger of safety; it isrepeled by immune system when it is injected to organism for a greatimmunogenicity. An injection with adenovirus vector with highconcentration, it leads to serious inflammatory reaction of liver. Viralvector such as liposome and polycation are commonly used lately. But,liposome and polycation have low specificness and targetness of genetransfer tissue, have lower transfection efficiency and short period ofgene expression, for they can be phagocytized by endothelial system.

许多的载体，病毒载体和非病毒载体以前已广泛应用，病毒载体主要包括腺病毒，逆转录病毒，腺相关病毒等；但病毒载体在安全性方面存在潜在的危险；免疫原性比较强，注射到机体后很快会被机体的免疫系统排斥，当静脉注射高浓度的腺病毒载体会使肝脏发生严重的炎症反应；非病毒载体目前常用的有脂质体及多聚阳离子聚合物；但脂质体和阳离子聚合物介导基因转移缺乏组织的特异性和靶向性，转染效率较低且易被网状内皮系统吞噬，基因表达时间短；因此研制新型的非病毒载体已成为研究的热点，纳米颗粒具有小尺寸效应，表面效应，随着颗粒直径变小，比表面积将会显著增大，故具有很高的化学活性，因而纳米成为了最有应用前景的非病毒载体。

Under inverted microscope, stereognosis of neurons died down, there were blank bulb in the neurons, dark particle were seen in the neuritis; the result of MTT test showed that the survival rate of neurons was obviously decreased. Res 40μmol/L increased the survival rate of neurons. Aβ(subscript 25~35) dose-dependently increased the level of MDA, decreased the level of GSH. Res dose-dependently increased the level of GSH, decreased the level of MDA.

结果：Aβ(下标 25~35)在终浓度为2μmol/L时神经元形态有明显的变化，细胞立体感减弱，胞体内空泡形成，细胞突起内可见黑色颗粒状物；细胞的存活能力明显下降，与对照组相比较有显著性差异(P.05)；Res在终浓度40μmol/L时，能明显提高细胞的存活能力。Aβ(下标 25~35)可以明显升高细胞培养上清液中MDA含量，降低GSH的含量；Res可使细胞培养上清液中MDA含量下降，GSH含量增加。

The results showed that:(1) some governing points, which were measured by submeter precision GPS, were utilized to correct the 1 m precision remote sensing image and it could satisfy the desired precision of geometrical correction, therefore, this method could be used as geometrical correction in the region where was short of the big scale relief map;(2) the density of the original data was the main factor to affect precision of the volume, and the precision of the calculated volume of earthwork could be improved to more than 90% when using the test points and feature points; the sparser the data density were, more significant could be improved; On the base that elevation of test points were measured by the submeter precision GPS, the error of the volume, which was produced by vectoring relief map to obtain DEM, could be calculated, and the calculation precision of the earthwork could be improved markedly.

结果表明：利用平面精度达亚米级的GPS测量控制点坐标对1米分辨率的遥感卫星影像进行几何校正，能够满足其几何校正的精度要求，可以解决缺乏大比例尺地形图地区的高分辨率遥感卫星影像的几何校正问题；通过对模型数据的分析，数据密度是影响体积精度的主要因素，利用检测点高程和特征点可以提高土方量计算的精度，使土方量计算的精度达到90％以上，数据密度越稀疏，精度提高越显著；采用高程精度达厘米级的RTK(Real Time Kinematic实时动态差分)测量检测点的高程，对用地形图扫描矢量化形成的DEM模型进行检测求出误差体积，可以大大提高土方量的计算精度。

So that the low temperature ion sulphurization technique can extend the service life of machine parts such as bearings, cutting tools, cylinder liners and piston rings of engine, gears, rollers, steel rings, etc.

渗氮＋渗硫复合处理可使渗硫层的持续时间显著延长，并能在各种速度条件下非常明显地提高表面的抗擦伤性能。

Similar to that, compared to the mouse model of memory impairments of acquisition, retention and retrieval induced by scopolamine, sodium nitrite and ethanol D-galactose, the blank control group, SZF group and positive control group could prolong the latency and reduce errors in step-down test and avoiding dark test.The result bioassay showed that SZF group incresed the activity of SOD and level of TChE and decreased the level of MAD in mice brain tissue.

东莨菪碱、亚硝酸钠和乙醇分别诱导的小鼠学习记忆获得、巩固和再现障碍实验结果表明，与模型组比较，在跳台和避暗测试中，空白对照组、SZF复方和阳性对照组均能延长跳台实验和避暗实验的潜伏期(P.01，P.05)，均能减少实验中的错误次数(P.01，P.05)。D-半乳糖、东莨菪碱、亚硝酸钠和乙醇诱导的小鼠脑组织生化测定的结果显示，与模型组比较有显著差异，SZF复方表现为能使脑组织中总SOD活力上升，MDA含量降低，TChE含量上升。

This study is the first to show that human thymic function can be significantly enhanced by GH therapy to produce new T cells.

这一研究首次发现，生长激素疗法能使人类胸腺的功能显著增强，产生新的T细胞。

The results of DLVO theoretical calculations indicate that the total acting energy between the titanaugite and ilmenite particles at pH 5.9 is negative, showing as attraction, which causes the superfine titanaugite particles attach on the surface of ilmenite. At pH 8.5, because of large electrostatic repulsion energy, the total acting energy shows as strong repulsion, thus the superfine titanaugite particles can not attach on the surface of ilmenite.

DLVO理论计算结果表明：当pH=5.9时，两种矿物颗粒间的总相互作用能为负值，表现为相互吸引，微细粒级的钛辉石会在钛铁矿表面上粘附，使钛铁矿的回收率显著降低；当pH=8.5时，由于静电排斥能大，总相互作用能仍表现为较强的排斥力，微细粒钛辉石不能粘附在钛铁矿表面。

DNA methylation on CpGs constitutes an epigenetic mark generally correlated with transcriptionally silent condensed chromatin.

DNA序列中CpGs结构的甲基化对表观遗传的调节具有显著作用，它可以使染色体转录沉默。

Unpromoted α-MoC(subscript 1-x) produced mainly CO2 and light hydrocarbons, addition of K2CO3 as a promoter, however, resulted in remarkable selectivity shift from hydrocarbons to alcohols.

结果表明，K改性使α-MoC(下标 1-x)催化剂的CO加氢选择性发生显著变化。

Trial in vitro made clear that it could remarkably increase the contractile of sphincter urethrae , inhibite the urinary bladder smooth muscle contraction and lower the baseline; when the mixture of Suo Quan Gu Niao was 25mg /ml, it could inhibit the urinary bladder strip contraction induced by KCL,too.

离体实验发现，缩泉固尿合剂在25mg/ml时能显著增强家兔尿道括约肌收缩力，并能抑制膀胱平滑肌的自动节律性收缩，同时可使平滑肌松弛，基础张力降低；对KCL引起的离体膀胱平滑肌的收缩具有一定的抑制作用。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。