使显著

Cd〓 (1, 10, 100, 1000μM) stimulated directly GtH secretion from pituitary of common carp in vitro, with the highest GtH secretion at 100μM, GtH secretion stimulated with 1000μM Cd〓 was not higher than that stimulated with 100μM Cd〓.The antagonism between Ca〓 and Cd〓 in perfusion of the pituitary fragments was not obvious.After being preperfusion with 100μM Cd〓(with or without Ca〓), the GtH secretion of the pituitary fragment was irresponsive to 2-min pulse stmulation of 10μM sGnRH-A.

鲤鱼脑垂体碎片离体灌流孵育实验结果显示，Cd〓（1，10，100，1000μM）可直接刺激鲤鱼脑垂体分泌GtH，灌流液中Ca〓对Cd〓的拮抗作用不明显，100μM Cd〓刺激脑垂体分泌GtH达到高峰，Cd〓浓度增加到1000μM时，脑垂体分泌GtH并没有进一步增加，甚至有减少的趋势；100μM Cd〓预灌流脑垂体后，可使脑垂体对2-min 10μM sGnRH-A刺激的反应性消失；1.25mM的EDTA可消除100μM Cd〓刺激脑垂体分泌GtH的作用；TFP和Cd〓同时灌流脑垂体一段时间后，撤除TFP可使脑垂体分泌GtH显著增加，即出现"反跳"现象。

At that time, politics overtopping economy and culture was the marked feature of the Chinese social mechanism, which deprived economy of its natural laws, and culture of its humanistic value. Economy and culture became the attachment to the political ideology.

当时，政治凌驾于经济和文化之上是中国社会机制的显著特征，这种社会机制使经济失去自然规律，使文化失去人文价值，经济和文化成为政治思想的附属物。

The main results were as follows:An appropriate concentration of ethephon sprayed on leaves of peanut made stems and branchs height shorter,but more branches;The fresh weight and dry weight per unit of leaf area and per plant increased;It optimized some physiological and biochemical characteristics in the leaves.It was showed that the ethephon increased obviously the contents of protein and chlorophyll and the activity of SOD and POD in the leaves,and improved the rates of photosynthesis and transpiration of the leaves,and increased the activity of the roots,but decreased the content of MDA in the leaves;It improved the quantity of pods,the percentage of plumy pods and the peanut yield.

结果表明：喷施适宜浓度的乙烯利可使植株相对矮化，抑制花生地上部分的生长，使主茎和分枝长比对照短，但分枝数较多；提高单位叶面积鲜重、干重以及植株鲜重、干重；优化花生植株的生理生化特性，表现为显著提高了花生叶片的蛋白质含量和叶绿素含量及SOD和POD活性，增强了花生叶片的光合速率和蒸腾速率，增强了主根活力，降低了花生叶片的丙二醛和可溶性糖含量；提高植株的单株结荚数、饱果率和产量。

However, MeJA treatment decreased DIMBOA and p－Hydroxybenzoic acid content of the third leaf significantly, while root DIMBOA content was increased significantly.

2MeSA处理叶片能诱导叶片中AOC基因、β－1，3葡聚糖酶基因（PR2a）基因及根中BX9基因的表达，使第三叶丁布含量降低，根中丁布含量升高，第三叶对羟基苯甲酸含量显著降低，6μL/L的MeSA处理则使根中香草酸含量升高。

γ -knife stereotactic radiotherapy and orchiectomy on moderate and far advanced prostatic cancer can make the cancer disappeared, slow down the advancement of cancer, improve uresis and decrease the prostate gland volume.

结论中晚期前列腺癌伽玛刀配合去势治疗，不仅能使肿瘤消退，缓解癌细胞生长，减慢病情进展，消除转移灶，而且能显著改善排尿症状，使前列腺体积缩小，无明显放射并发症。

Results Bestain could significantly lower the serum DHBV level. ALT and AST in serum were reduced during the treatment. Examination of DHBV DNA in liver with Southern Blot indicated Bestain could inhibit DHBV DNA replication.

结果 乌苯美司用药1月能使血清DHBV DNA总体水平显著降低；治疗期间同一时相内，能使血清ALT明显降低；Southern Blot检测肝组织内DHBV DNA，其结果提示该药能抑制病毒在肝内的复制。

Tapping his 20-year industry experience and leadership with electronic trading systems, Greifeld has led a significant enhancement of NASDAQ's trading offerings. In March 2004, he oversaw the launch of NASDAQ's market center—a newly integrated system capable of trading of NASDAQ, NYSE, AMEX-listed securities and exchange traded funds on a single electronic platform. Most recently, in May 2004, Greifeld led NASDAQ's decision to acquire BRUT ECN from SunGard Data Systems.

格雷费尔德利用自己20年来积累的行业经验和在电子交易系统的领导才能，使纳斯达克的交易产品数量有了显著增加。2004年3月，他发起创立了纳斯达克市场中心，使在纳斯达克、纽约证券交易所、美国证券交易所上市的证券和交易所交易基金都能在同一个电子交易平台上进行交易。2004年5月，格雷费尔德领导下的纳斯达克决定收购SunGard数据系统公司旗下的BRUT ECN。

More than 30% can increase the capacity for liquor; this product contains puerarin, Hovenia dulcis Thunb, chrysanthemum speed of alcohol metabolism, increasing blood flow, so to speed up the excretion of ethanol; its active ingredient a variety of a large number of isoflavones, flavonoids and saponins active ingredient, can inhibit the gastrointestinal absorption of alcohol, promote blood circulation, so to speed up the excretion of ethanol, significantly reduces the concentration of alcohol in the blood, promoting the role of ethanol clearance.

可以提高酒量30%以上；本产品含有葛根、枳椇子、菊花加速酒精代谢，增加血流量，使乙醇得以加速排泄；其有效成分多种大量异黄酮类、黄酮类物质和皂甙类活性成分，能抑制肠胃对酒精的吸收，促进血液循环、使乙醇得以加速排泄，显著降低乙醇在血中的浓度，促进乙醇清除的作用。

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

Compared to the patch dealt with glutaraldehyde, the autologous pericardial patch treated by distilled water is living, and calcification is not easily to happen. At the same time, after treated by distilled water, pericardial patch is incrassated mildly, and can be handled easier than fresh pericardium. The early-moderate team results of reconstruction of RVOT using autologous pericardial monocusp patch treated by distilled water are satisfactory.

使用蒸馏水处理自体新鲜心包组织，可以使心包组织轻度水肿增厚，相对不易皱缩卷曲，既摒弃了新鲜心包组织使手术操作不易进行的缺点，又保持了新鲜心包组织具有活性、生物相容性好、相对不易钙化的优点，避免了蛋白交联剂处理后的心包组织生物相容性差，易于发生钙化的缺点，简便易行，效果显著。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务，你就做你的事好了。