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When they are released into the extracellular environment, or when they are membrane-bound and in contact with the pericellular zone, these enzymes degrade a broad range of connective tissue proteins and are important during the development of healthy tissue as well as in remodeling damaged tissue.

当它们被释放入细胞外环境,或者是与膜结合后与细胞外环境保持接触时,这些酶能够使大范围面积的结缔组织蛋白酶降级,这样对健康组织的发育以及对受损组织的重塑相当重要。

The expression of AT2R gene can be regulated efficiently in vivo by local delivery of MSC with dual-stable expression of AT2R gene, thus reduces the formation of intimal hyperplasia.④AT2R gene can influence the expression of ECM and significantly promote the cellular apoptosis in the injury rat carotid artery.⑤These data demonstrate the clinical potential of AT2R regulatable expression to prevent restenosis after PCI.

研究结论:(1)与VSMC直接接触可以诱导MSC向血管成分细胞分化;(2)构建的Dox-on可调控的MSC细胞株诱导活性可靠,使外源AT2R基因的表达处于有效的主动控制下;(3)局部导入MSC不影响球囊损伤后大鼠颈动脉新生内膜增生;(4)由MSC介导的AT2R可调控表达受到Dox的良好调控,可有效抑制球囊损伤后大鼠颈动脉新生内膜增生;(5)AT2R影响血管损伤后修复时ECM成分的表达,并促进细胞凋亡的发生,可能是AT2R介导抑制新生内膜形成的机制。

In a word, the greening of residential area should take advantage of the plants' purify, beautification and protective function, making people's daily life every detail and greening in close contact with each other,let residental area is no longer drab, but a complete green ecological system, various kinds of color is the plant, flowering plants, shade plants to create landscape, it is pleasant to create a harmonious natural inhabitants of ecological living space.

总之,居住区绿化要充分发挥植物的净化、美化及防护功能,使人们日常生活中每一细节与绿化密切接触,让居住区绿化不再是一两块单调的绿地,而是一个完整的绿地生态系统,是用各类色叶植物、开花植物、遮阴植物等营造出的怡人景观,是为居民创造的一个和谐自然的生态居住空间。

The Nature of Personal Reality 1974 The quintessential Seth book, it expands on the topics brought up in Seth Speaks and is filled with exercises to get you better in touch with the Sethian philosophy.

个人现实的本质》,1974年。这是赛斯书的精髓,它扩展了《赛斯说》中提到的话题,并配有练习,使你更好地接触赛斯哲学。

During the latter part of its flight, the sley is moving forward and rising, and this helps to maintain contact between the shuttle and the reed and raceboard and thus ensure that the shuttle is boxed correctly.

在梭子飞行的最后阶段,筘座向机前运动,其位置上升,有助于使梭子与钢筘及走梭板的密切接触,有助于梭子准确地进入梭箱。

When we used a glass pipette to clean off extracellular materials overlying the somata before recording,individual amperometric spikes induced by 1μM HCRT were detected.

当用玻璃电极吹去神经元胞体表面的组织,使碳纤电极紧密接触细胞表面,可以记录到HCRT引起的单个尖峰发放。

Relationship and cater to leaders.(Don't consider yourself as the center of world,leaders is not so correctly speeching as you).If what i metioned is defined as apple-polishing ,then ,i will completely trust it infinitely.

而且既然拍马屁能够使你得到更好得发展机会,也可以深入接触领导的想法,以此提高自己得认识和考虑(当然前提条件是你不是草包),为什么我们不能拍马屁。

24 New Zealand white rabbits were divided into control group,Saline group and Mailuoning group,on the latter two groups the models of Hemifacial spasm were made by the temporal superficial artery closely contacting the main trunk of facial nerve at stylomastoid foramen.From the 5th week,the Saline and Mailuoning were injected intravenously into ear margin for 2 weeks on Saline and Mailuoning group respectively.At the 7th week,the MDA and SOD in serum were measured,meawhile the microstructure and ultrastructure of facial nerve were observed on 3 animal groups.

将24只新西兰大白兔随机分为对照组、脉络宁组和生理盐水组,在手术显微镜下分离出其茎乳孔处的面神经主干和颞浅动脉,使二者密切接触,以制备半面痉挛动物模型;术后第5周起对脉络宁组和生理盐水组分别自耳缘静脉推注脉络宁注射液和生理盐水持续2周;第7周取3组动物血清测定丙二醛和超氧化物歧化酶,并处死取材行面神经光、电镜观察。

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究,我们提出了初步的NodD操纵子激活模型:第一,四聚体是NodD蛋白的功能单位,它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子;第二,小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体,在我们的模型中,NodD四聚体缩小其V形主体的弯折角,进而缩短其DNA结合功能域的间距;第三,小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用,NodD的构象改变由蛋白质经其双铆钉位点传递给DNA;第四,只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物;第五,不排除NodD与RNA聚合酶可能有直接的相互接触位点,不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物,但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

A method for producing fatty acid alkyl esters and/or glycerin comprising a step of bringing a fat or oil into contact with an alcohol in the presence of a catalyst, wherein the catalyst is at least one catalyst selected from the group consisting of the following to: a metal oxide having an ilmenite structure and/or a slyrankite structure; an oxide containing a metallic element belonging to the Group 12 and a metallic element belonging to the Group 4; a mixed oxide containing a metallic element belonging to the Group 12 and a tetravalent transition metallic element; a metal oxide containing zirconium and at least one metallic element selected from the group consisting of metallic elements belonging to the Groups 4, 5 and 8; and a metal oxide containing anatase type titanium oxide and/or rutile type titanium oxide, and the metal oxide containing a sulfur component of 700 ppm or less.

脂肪酸烷基酯和/或甘油的制造方法包括在催化剂的存在下使脂肪或油与醇接触的步骤,其中,所述催化剂是选自由下列~所组成的组中的至少一种催化剂:具有钛铁矿结构和/或斯里兰卡石结构的金属氧化物;含有属于第12族的金属元素和属于第4族的金属元素的氧化物;含有属于第12族的金属元素和四价过渡金属元素的混合氧化物;含有锆和选自由属于第4、5和8族的金属元素所组成的组中的至少一种金属元素的金属氧化物;和含有锐钛矿型氧化钛和/或金红石型氧化钛的金属氧化物,并且所述金属氧化物含有的硫成分为700ppm以下。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。