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There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体,分别为ET-1、ET-2、ET-3、ET-β,而在人主要是ET-1,在生理条件下,ET-1在血浆中含量较低,约为5ng〓,故ET-1不是一个循环激素,而是局部合成释放,局部起作用的活性物质,半衰期约1小时,ET-1是目前已知的最强的血管收缩剂,对静脉的作用比动脉强,在血管床,ET受体有A、B两型,A型主要分布在平滑肌细胞,B型主要分布在内皮细胞,它可以通过旁分泌途径刺激内膜增生,具有有丝分裂原效应,可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩,使静止期SMC进入增殖期,还可以通过信号传导途径,与bFGF、GTF-β、PDGF等生长因子协同作用,起共有丝分裂原作用。

Circulating perfectible search mode can enrich cascading failures collection,and makes it possible realize the comprehensive predicting and searching for cascading failures of the power grid,and offers technical support for dispatchers to take correct decision-makings as soon as possible.

循环完善搜索模式可以使连锁反应事故集不断地充实完善,使电网连锁故障的全面预测搜索成为可能,进而可为运行人员及早采取正确的决策措施提供技术支持。

The dynamo runs at rull speed to drive main shaft,then the main shaft makes the emulsifying wings in emulsification grove rotate,which absorbs the liquid in its brand groove into ring groove through guide vanes on upper and lower side s of the groove.The v

由电动机全速运转带动主轴,经主轴转动乳化框槽内之乳化翼片,使其将桶槽内之液体经框槽上、下两侧之导流叶片吸入环状框槽内,经以主轴为中心高速圆周旋转叶片;连续使乳化翼端刀面与乳化框间极小之间系高频率之强力切割剪断、粉碎,再借叶片高速离心旋转排挤,持续循环混合,以极短之时间即可完成均质乳化之处理。

Large scale CFB boiler baker is a key process to make anti-erosion refractory s intering, shaping and attain its performance of heat resistance, pressure resist ance, erosion resistance, torsibility and shock-proof.

大型循环流化床锅炉的烘炉是使耐火耐磨材料烧结成型并使之达到耐火、耐磨、耐压、抗折、热震稳定性、高温耐压性能的关键。

The happy mood can affect the nervous system the activity, thusinfluence hormone the secretion,causes the blood vessel circulation unobstructedly, the skin nutritionis sufficient; Also can promote the epidermal cell to split, theenhancement storage hypodermic fat function, enable the skin to changethe exquisite favor also to have the elasticity.

愉快的心情能影响神经系统的活动,从而影响激素的分泌,使血管循环通畅,皮肤的营养充足;还能促进表皮细胞分裂,增强储存皮下脂肪的功能,使皮肤变得细腻润泽且有弹性。

Liposome properties and biological behaviors can be controlled by surface modification. Attachments of hydrophilic polymers, such as poly, enable them to have a prolonged circulation time without being opsonized and recognized by mononuclear phagocytic system.

通过表面修饰可以改变脂质体的性质和生物学行为:在脂质体表面修饰亲水性高分子可以阻碍血浆成分的调理作用,减少脂质体被网状内皮系统识别和摄取,使脂质体具有长循环的特点;在脂质体表面修饰特异性的配基,能使脂质体具有主动靶向的特性。

Under the electromagnetic force the angle steel and the steel plate, in puts in gallbladder which the steel plate makes, in the gallbladder is uses sets up the salt bath which the brick and the standard brick compose, in the gallbladder is mainly uses in preventing the fused salt permeating heat insulating

三项埋入式电极盐浴炉采用盐类作加热剂,根据不同的工作温度,可选用不同成份的盐或混合盐,盐在熔化前是不导电的,因此盐浴炉使用时必须使用起动电极溶化,由于电流通过导电的溶盐不断产生热量,故可保持溶化状态,因电极在电磁力的作用下,通过自然对流和电磁搅拌而使熔盐不断循环,故可迅速和均匀的加热工件。

The hot water steeps feet, can extend human body breath a way the hair thin blood vessel which glue a film more and quickly, speeding blood circulation, making thus the breath way germ and virus which glues the white cell in blood inside the film to exterminate to invade a human body in time, make human body don't need be subjected to infection.

热水泡脚,可较快地扩张人体呼吸道粘膜的毛细血管,加快血液循环,从而使呼吸道粘膜内血液中的白细胞及时地消灭侵入人体的细菌和病毒,使人体免受感染。

The ring is rolled by drive roller and mandrel roller, drive roller offer rotation to make ring rotate continuously and mandrel roller offer line feed to make the ring wall become thinner and thinner. The guide roller ensure the ring rolled comfort, and inspect roller check the rings diameter whether reach the limit dimension.

主动辊提供转动,使环件变形区不断循环周而复始的通过轧辊孔型;芯辊提供直线进给运动,使环件壁厚不断减小以实现环件直径扩大的加工过程;导向辊保证轧制平稳进行,检测辊测量轧制环件尺寸是否达到要求以停止轧制。

The highly efficient Atkinson-cycle engine, made possible by the Variable Valve Timing with intelligence system, allows the expansion/power stroke to be longer than the compression stroke so that combustion energy can be more effectively used for production of engine power.

高效的阿特金森循环发动机,作出与智能可变气门正时系统,可以使扩充/动力冲程要长于压缩冲程,使燃烧的能源可以更有效地用于生产发动机力量。

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推荐网络例句

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。