作用的

Objective To investigate antitumor activity and molecular mechanism of deguelin to the human U937 leukaemia cells and to explore the mechanisms regulating cell cycle and nucleoporin 98 （Nup98） and nucleoporin 88 （Nup88） in vitro.

目的研究鱼藤素对人类白血病细胞株U937细胞体外抗肿瘤作用，研究其引起细胞周期与核孔蛋白Nup98和Nup88的改变，探讨其抗癌作用的分子机制。

In this paper, the mechanism of dicarboxylic acids and metal ions inhibiting CaOxa crystal was discussed.

本文在理论上讨论了二元羧酸抑制剂及金属离子对草酸钙结石的作用机理，为设计羧酸类药物以及与碱性金属离子联合作用的药物提供理论依据。

Hematoxylin alcoholl extracts with different concentration were co-cultured with lung cancer A549 cells in order to observe effects on cell proliferation by using MTT method, study the effects on cytotoxicity and apoptosis of lung cancer A549 cells using optical microscope, phosphatidylserine ecstrophy analysis and cell period analysis.

将苏木醇提物按不同浓度分别同人肺癌A549细胞共同培养，MTT法检测对细胞增殖作用的影响，光学显微镜、细胞膜磷脂酰丝氨酸外翻分析、细胞周期分析观察不同浓度苏木醇提物对人肺癌A549细胞的细胞毒和调亡作用。

Objective: To investigate the biological effects of aspirin on esophageal carcinoma cells and the possible mechanism.

目的：探讨COX-2抑制剂阿司匹林对食管癌细胞作用的生物学效应及可能的作用机制。

Objective TO observe the regulative effect of lipid metabolism and the protective effect of huangqin exactive on mice of STZ induced diabetes.

目的 观察黄芩提取物对STZ糖尿病小鼠脂代谢的调节作用和抗氧化保护作用的影响。

Only unbound drug is thought to be available for passive diffusion to extravascular or tissue sites where pharmacologic effects occur.

一般认为，只有非结合药物才能通过被动扩散到达产生药理作用的血管外或组织部位，因此，非结合型药物浓度和药物效应以及和作用部位的药物浓度关系更密切。

Objective To explore the role of tumor necrosis factor-α in the pathogenesis of hepatorenal syndrome.

目的 探讨肿瘤坏死因子-α及肝素对内皮素-1（ET-1）收缩肾脏血管作用的影响，研究TNF-α在肝肾综合征发病机制中的作用。

To further investigate whether cyclin A played as a key molecular in cell proliferation, HL-60 cells were exposed to different concentrations of hexamethylene bisacetamide.

为了进一步研究cyclin A在白血病细胞增殖中的作用，用在体内、体外均有抗肿瘤作用的六亚甲基二乙酰胺在体外抑制白血病细胞系HL-60增殖，并诱导其分化。

Incurrent research, aiming at the rupture problem engendered in the shooting process of acertain 5.56mm automatic rifle, the strain and stress distributions on the cartridge caseunder the action of axial pull have been analyzed. Based on the theories of elastic-plasticmechanics and contact mechanics, a mathematic and physical model of the cartridge-caseand chamber system has been set up; and based on the platform of the general softwarepackage APDL of ANSYS for finite element analysis, a parameterized model of thecartridge-case and chamber system has also been established. The method for nonlinearFEA has been adopted to analyze the stress distribution on the entire cartridge-case andchamber system, and the method of contact element has been employed to investigate thecontact stress between the cartridge case and chamber, and then the influences of frictioncoefficient and locking space on the static and dynamic stress and strain response of thecartridge case and chamber to the action of power gas have also been discussed. On thebasis of a lot of numerical tests, a kind of element Plane13, which is concentrated incoupled computation of heat and construction, has been used finally to simulate thetransient response of the cartridge-case and chamber system to the power gas. Throughloading the temporary thermal characteristics of explosive gas in the procedure of emulate, the corresponding transient thermal stress distributed on the entire system under thecombined load of transient thermal stress and transient pressure has been obtained. Owingto these comprehensive considerations, the numerical results obtained in this paperrepresent the actual situations comparatively exactly.

本文针对某5.56mm自动步枪在工作中出现断壳的问题，分析了弹壳在轴向拉力作用下的应力应变；基于弹塑性力学及接触理论，建立了弹壳弹膛系统的数学、物理学模型，在通用有限元ANSYS软件的参数化建模工具APDL平台上，建立了弹壳弹膛系统的参数化模型；采用非线性有限元法计算了弹壳弹膛系统的整体应力，引入接触单元法分析弹壳和弹膛的接触压力，探讨了在不同的摩擦系数和不同的闭锁间隙对弹壳弹膛静、动态响应的影响；本文进行了大量的尝试，最后确定采用热、结构耦合单元Plane13，在计算中加载了火药气体的温度历程，成功的获得了弹壳弹膛系统在瞬态的热载荷和瞬态的压力载荷同时作用下弹壳弹膛系统的热应力数值解，考虑因素全面，比较真实的反映了弹壳弹膛系统在火药气体压力和热载荷下作用的情况。

Japan semiconductor tradeconflict in 1980s and the making of North American Free Trade Agreement in early 1990s, the thesis aims to demonstrate the application of role theory, the bureaucratic politics and the interbranch politics models in examining a bureaucratic agency's role in the process of trade policymaking.

通过对贸易代表办公室在上世纪八十年代美日半导体贸易冲突和九十年代北美自由贸易协定制定过程中所起作用的两个案例分析，作者旨在证明运用角色理论、官僚政治模式和跨机构政治模式讨论决策机构在贸易决策过程所起作用的可行性。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。