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BACKGROUND: Previous studies demonstrate that inducible nitric oxide synthase and NO play important roles in both the occurrence and the recovery of acute soft tissue injury; however, their effect on the recovery of chronic injury, especially, the influence of aminoguanidine on recovery of acute soft tissue injury remains unclear.

背景:研究表明,诱导型一氧化氮合酶及一氧化氮在急性软组织损伤及其修复过程中起到重要的作用,但目前有关其在慢性软组织损伤修复过程中的作用,及氨基胍对其作用的影响尚不明确。

Allium(Allium sativum L.)is a kind of buld which belongs to liliaceae.It has some pharmacological actions,such as antibiosis antivirus antioxygenation and antitumor,which has many different mechanism.And suggested that allicin has wide foreground in antitumor.

大蒜是百合科属植物的鳞茎,具有多种药理作用,如抗菌、抗病毒、抗氧化、免疫以及抗肿瘤作用,其中抗肿瘤作用的机制不尽相同,其在抗肿瘤方面有着广阔的前景。

The incidence rates and duration of ventricular dilation-induced arrhythmias in each of verapamil, chelerythrine or glibenclamide group were similar to those in control group. Conclusion Ventricular dilation may induce arrhythmias in isolated rat hearts, which is inhibited by ischemic preconditioning. The transient increase in [Ca(superscript 2+)] appeared to be a triggering factor in the process of ischemic preconditioning. K channel PKC might also play an important roles in this process.

对大鼠心室进行膨胀可诱发心律失常;缺血预适应对心律失常的发生具有抑制作用;细胞内钙离子浓度的短暂升高可能是缺血预适应发挥抑制作用的驱动因子;ATP敏感性钾通道及蛋白激酶C在缺血预适应过程中可能发挥了重要作用。

Using assay of 21 Wistar rats from diarrhea intestine separation, pure culture of bacteria in the intestine containing 1% were small thorn Hericium erinaceus polysaccharide fermentation broth and 1% fermentative polysaccharide liquid medium 37 ° C for 18 h after the OD value, Statistical analysis showed Hericium and see 21 species of Ganoderma intestinal bacteria strains of the five species of a clear inhibitory effect other strains of the role is not obvious, Ganoderma and Hericium compared Hericium no significant role in the strain Ganoderma and there are obvious inhibition, Hericium and prominent role in the strain.

采用比浊法测定了21种从腹泻Wistar大鼠肠道内分离、纯培养的肠道细菌在分别含有1%小刺猴头菌发酵液多糖和1%灵芝发酵液多糖的培养基中37℃培养18h后的OD值,经统计分析结果表明见猴头和灵芝对21种肠道菌中的5种菌株有明显的抑菌作用,而对其他菌株的作用并不明显,灵芝和猴头相比较,猴头没有显著作用的菌株,而灵芝却有显的抑制作用,而猴头具有显著作用的菌株。

A new theoretical model, the 2CLJDQP potential function, was developed for linear molecules, which takes into account dipole, quadrupole and induction effects as well as the rotation of the dipole out of the molecular axis. The energy parameters were optimized for various types of fluids. With the modified mixing rules, the potential parameters obtained from homonuclear molecules can be used to calculate the second virial coefficients of heteronuclear molecules. The model was also successfully extended to triatomic molecules. Analysis of the contributions to the second virial coefficients of long-range interactions shows that the molecular interactions introduced in the present model, such as, the induction effects, cannot be neglected.

建立了全新的线型分子2CLJDQP势能模型,考虑了偶极作用、四极作用及诱导作用的影响,还考虑了极轴与分子轴不平行的情况;回归了多种线型分子的势能参数;通过改进混合规则,可应用同核线型分子的势能参数直接计算异核线型分子的第二维里系数;扩展该模型可用于线型三原子分子计算;讨论了各长程引力项对第二维里系数的贡献,结果表明本模型引入诱导作用等是十分必要的。

New antifungal agents have been developed over the past years based on the discovery of many new target sites of Candida albicands. For example, Echinocandins, aiming at the cell wall of Candida albicands, showed strong antifungal activities to fluconazole resistant candidas and fungal biofilm. Moreover, because β-glucan synthase does not exist on the cell membrane of mammalian cells, Echinocandins has a low toxicity and a promising clinical future. Though the mechanism of Histatin is not clear, it has strong activity not only on candida resistant of polyene and azole, but also to Candida parapsilosis, Candida krusei and Cry ptococcus neoformans. Berberine and Ocimum gratissimum L. were also found to have prominent anti-fungi activities.

近年来相继提出了许多抗白念珠菌药物作用的新靶点并成功开发出一些活性强大,疗效确切的抗真菌药,如以真菌细胞壁为靶点开发出棘白菌素类药物卡泊芬净、米卡芬净等,该类药物主要抑制β-葡聚糖合成酶,体外对氟康唑耐药的念珠菌属及真菌生物被膜表现出强大的抗菌活性,又由于β-葡聚糖合成酶在哺乳类动物细胞内不存在,故具有高效低毒的临床效果,是一极具前途的新型抗真菌药;以真菌细胞膜为靶点开发出Histatin类药物,虽然作用机制目前还不完全明了,但其作用不同于临床常用的多烯类和氮唑类,并已经发现Histatin5对两性霉素B和氮唑类耐药的念珠菌有效,并且对非白念珠菌如光滑念珠菌、克柔氏念株菌、隐球菌等也有杀灭作用;通过对植物药物的研究发现黄连素和丁香罗勒Ocimum gratissimum L。

Test results show that the shear strength parameters of the fly ash with high calcium oxide content can make a notable change due to pozzolanic action and frost and thaw cycles, but for the fly ash with low calcium oxide content this phenomenon is not very obvious,and the influence of the frost and thaw cycles can be neglected.

试验结果表明,高氧化钙含量的粉煤灰的强度指标受上述两种作用的影响显著;低氧化钙含量的粉煤灰的强度指标在凝硬作用下也有所提高,但基本不受冻融作用的影响;干贮粉煤灰的渗透系数受凝硬和冻融作用的影响较小。

The main creating aspects are finding and clarify such a fundamental physical process that the grain boundaries emit vacancies under compressive stress to induce solute non-equilibrium grain boundary dilution and absorb vacancies under tensile stress to induce non-equilibrium grain boundary segregation, formulizing the structural equations and the composition equations in force equilibrium in grain bounary region to describe this physical processes and the kinetic equations for non-equilibrium grain boundary segregation under tensile stress, calculating the modulus in grain boundary region from the expermental data of grain bounday segregation using the structure and coposition equations and calculating the diffusion coefficients of vacancy-solute atom complexes using the kinetic equation simulating the experimental results of grain boundary segregation.

本项目的主要创新点是,发现并阐明了弹性应力场作用下空位与晶界交互作用的基本物理过程:在张应力作用下,晶界会吸收空位,引起溶质非平衡晶界偏聚;压应力作用下,晶界会发射空位,引起非平衡晶界贫化。建立了描述此物理过程的晶界区力学平衡的结构方程和成分方程;?建立了张应力引起的非平衡晶界偏聚动力学方程?;用晶界区力学平衡的结构方程和成分方程?,首次通过实验测量计算出多晶材料晶界区的弹性模量;通过建立的动力学方程模拟实验结果,首次获得溶质原子-空位形成的复合体的扩散系数。

In details, the strongest inhabitation to the shoot growth was observed when neutral soluble fractionates were supplied. The shoot biomass with neutral soluble fractionates added was decreased by 10.52% over the blank control, resulting in obvious increase of root: shoot ratio. It suggests that the root exudates would be self-poisonous. Besides, both acid and alkaline soluble fractionates exhibited the trend to increase the stem height and it is necessary to exploit the reasons.

在培养液中,分别加入分组的烤烟根系分泌物,均显著降低根系对NO_3~-、H_2PO_4~-、K~+离子的吸收和根系活力,推测根系分泌物中产生抑制作用的物质可作用在相当宽的pH范围;其中,碱溶性组分对H_2PO_4~-、酸溶性组分对K~+、中性组分对NO_3的吸收和根系活力的抑制作用较强,推测在烤烟根系分泌物中,可能存在多种抑制烤烟生K和养分吸收的化学物质;另外,抑制作用随着根系分泌物浓度的增加而增强。

The highest occupied molecular orbit and the lowest unoccupied molecular orbit are calculated, and the energy gap of the two orbits determines the activity of the reagents, and yet, in an alkaline solutions for flotation, the HOMOs of the corresponding ions decide the rigidity of the reagents and therefore determine the reaction activity with different rigidity metal cations in minerals, which vary flotation performance to different minerals, and the experimental results were verified.

药剂与矿物作用的能量计算结果表明:苯氧乙酸类抑制剂与方解石和一水硬铝石作用后的能量变化均为负值,能量变化有利,可以形成稳定的吸附;而与黄铁矿作用后的能量变化为正,能量的变化是不利的,故不能形成稳定的吸附,表现出较弱的抑制作用。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。