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The human cartilages are composed of chondrocyte and extracellular matrix , the form of chondrocytes are hypertrophy and the quantity are less; the ECM of cartilage are compised of type Ⅱ collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury, the ommilayer injury ofcartilage can be recovered by marrow, but because of without stimulation mechanism, the new tissues are merely fibrocartilages, they can not be coincide with hyaline cartilage in menchanics; the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation, thus, the plerosis of articular catilage can not depend on the proliferation of local chondrocyte. Ever since, people tried their best to find a way to reconstruct articular cartilage.

中文题名人骨髓基质干细胞成软骨诱导及多孔复合材料作为细胞载体的体外实验研究副题名外文题名 Cartilage induction of human mesenchymal stem cells and experiment on compound porous materials as cells' scaffold in vitro 论文作者刘晓岚导师周江南学科专业外科学研究领域\研究方向学位级别博士学位授予单位中南大学学位授予日期2003 论文页码总数68页关键词骨组织工程软骨细胞骨髓基质干细胞壳聚糖高分子外消旋聚乳酸馆藏号BSLW /2003 /R68 /10 造成人体关节软骨损伤的原因主要为创伤和关节炎,关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复,但这种修复由于缺乏相应的刺激机制,只能形成纤维软骨,而不能形成符合关节生理、力学要求的透明软骨;单纯软骨部分损伤软骨组织内无血管,软骨细胞迁移迟缓,无法使损伤区域软骨细胞再生,因此,关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

Furthermore, preliminary work also performed to examine whether PI3K/AKT signal transduction pathway was activated in the process of refractory leukemia development. Materials and methods An immortalized human bone marrow stromal cell line, HS-5, was introduced to establish a bi-phase culture system for the cultivation of B-lineage precursor leukemia cells. ELISA and RT-PCR were used to investigate the expression of VEGF and its receptors in the leukemia cell lines and primary childhood leukemia cells in different treated groups. Flow cytometory method and immunofluorescent staining were employed to examine the apoptosis signals both in the VP16 treated and untreated leukemia cells. Western blot was utilized to explore the PI3K/AKT activated status in the drug induced or uninduced leukemia cells and lymphocytes from healthy donors.

材料和方法使用来源于人类骨髓基质细胞的细胞株HS-5作为滋养层细胞进行急性淋巴细胞性白血病细胞的体外培养,通过细胞生物学和免疫学方法评估培养体系并鉴定出难治性白血病细胞克隆;以ELISA和RT-PCR方法检测急性白血病细胞株和患儿白血病细胞VEGF及其受体的表达,了解不同治疗阶段VEGF及其受体的表达状况,并结合临床指标进行分析,明确VEGF及其受体在白血病发生过程中的作用;流式细胞仪和免疫荧光染色法对正常健康儿童、初发白血病患儿、复发白血病患儿及缓解后患儿进行凋亡因子检测和分析,初步阐明难治性白血病抗凋亡形成的原因;蛋白印记分析检测PI3K/AKT信号传导通路在健康儿童、初发白血病和复发白血病患儿的表达,初步了解难治性白血病形成的分子生物学机制。

Some views think MBO have cheating operation that lead to the state assets losses; I think MBO , as a kind of comparatively ripe system , its must not cause the loss of state assets , the objective factor influenced state assets price is much, higher or lower than net assets price may not reasonable , may not unreasonable either, the cause leading the loss of state asset is unsufficiency condition and not canonical means. We should consider interior employee especially outstanding the historical contribution factors of administrators.

笔者认为MBO作为一种较为成熟的制度,其本身并不必然导致国有资产流失,但国内影响国有资产合理定价的客观因素多而复杂,国有资产转让价格高于或低于净资产未必合理,也未必不合理;国有资产流失的原因是在条件不充分的情况下,用不规范的方法实施MBO;某些企业作低价是因为考虑了内部职工尤其是优秀管理者的历史贡献因素;当前首要目标是改制,提高社会整体经济效益,应在合理范围内以法律形式明确管理层收购价格优惠制度,促进MBO的顺利进行。

Thinking of this, based on the theories of generation relationships of anthrop...

本研究结合人类学和社会学关于代际关系的相关理论,围绕&近代中国社会代际关系&的命题展开,以&五四时期知识分子的代际冲突&为具体的研究对象,用报纸杂志、人物往来书信、著作等作为主体材料,通过分析知识分子思想表达的方式,揭示出知识转型导致代际关系变化这一深层次原因,并就与中国社会代际关系相关的若干问题提出自己的看法。

This is permissible although "pure reason," as was the case with the same use of terms in our first work, is only intended to denote reason in its theoretical employment, and although there is no desire to bring under review its faculty as practical reason and its special principles as such.

虽然这是允许的&纯粹理性&,这一点与我们的术语使用的第一部作品相同的情况下,仅用于表示在其理论就业的原因,虽然没有欲望,使审查其作为实践理性的教师并作为其特殊的原则等。

It is box of this machine top, the Venus that is the old Microsoft that lets world software industry first plans to fold halberd heavy sand in China, do not have soundlessly breath, without result and return, lose face; greatly next, again the UTSTARCOM that in China's very famous beautiful beard entrepreneur Wu Ying leads centers firepower onslaught, final and same also be hold the bag, the tear asperses battlefield; but, regard game of a network as the company, because one lets the outside look unidentified the matter that wants not to understand, appear on the market in the success grandly later, also abandoned unexpectedly oneself bilk the network game with succeeding, in tying the grand case that took this to be less than light soon directly.

就是这个机顶盒,先是让世界软件行业的老大微软公司的&维纳斯计划&在中国折戟沉沙,无声无息,无功而返,大丢颜面;然后,又有在中国非常闻名的&美髯企业家&吴鹰领导的UTSTARCOM集中火力猛攻,最终同样也是两手空空,泪洒疆场;但是,作为一个网络游戏公司,因为一个让外界看不明想不懂的原因,盛大在成功上市之后,居然也抛弃了自己赖以成功的网络游戏,一头扎进了这个一眼看不到亮光的&盛大盒子&中。

Tier rating: Tier 2 Watch List - China is on the Tier 2 Watch List for the fourth consecutive year for its failure to provide evidence of increasing efforts to combat human trafficking, particularly in terms of punishment of trafficking crimes and the protection of Chinese and foreign victims of trafficking; victims are sometimes punished for unlawful acts that were committed as a direct result of their being trafficked, such as violations of prostitution or immigration/emigration controls; the Chinese Government continued to treat North Korean victims of trafficking solely as economic migrants, routinely deporting them back to horrendous conditions in North Korea; additional challenges facing the Chinese Government include the enormous size of its trafficking problem and the significant level of corruption and complicity in trafficking by some local government officials 2008

三层评价:第2级观察名单-中国是第2级观察名单连续第四年其未能提供证据证明越来越多的努力,打击贩卖人口,特别是在惩治贩运犯罪和保护中外贩卖活动的受害者;受害者有时惩罚非法行为,承诺的直接原因是他们被贩卖的,如卖淫或违反移民/移民管制;我国政府继续处理朝鲜贩卖活动的受害者仅仅作为经济移民,经常驱逐他们回到可怕的条件下在北朝鲜面临更多的挑战包括:中国政府的巨大规模的人口贩运问题,相当程度的腐败和共谋贩运一些地方的政府官员

Do not always arise from the immediately perceptible cause which the world assigns, but are the culmination of principles which have been working in the minds of men for many years, until at last the proper time and propitious surroundings kindle the latent truth into life, and, as the light of reason flows from mind to mind and the unity of purpose from heart to heart, enthusing all with a mighty common cause and moving nations as one man to the accomplishment of great ends.

并不总是出现,从立即感知的事业,世界指派,但高潮的原则,一直致力于在人的头脑中的男子多年,直到去年在适当时间和适当的环境,点燃潜在的真理,生活,而且,正如因流动原因,从下定决心的头脑和团结的目的,从心脏到心脏, enthusing所有与一支强大的共同事业和移动联合国作为一名男子,以完成伟大的结束。

The article talks from the new changes in working environment of Moral Education in the and challenges of the content and method on Moral Education in Colleges under the new situation, uses the moral theory and methods - Marxsim Philosophy and materialistic dialectic. Through the study of the status quo in and abroad and learning from advanced foreign experience, analysis the reasons for the problems on China's Moral Edu...cation in Universities and then builds a new situation to enhance the effectiveness of moral education of University of counter measures concept. Finally it forms a clear set of the College Moral Education optimization system including moral education goals definitude, the contents of moral education enriching, curriculum strengthening, channels outreaching, methods of work innovativing, and working contingent strengthening.

文章从新形势下高校德育工作环境的变化和高校德育工作内容与方法面临的挑战谈起,用高校德育理论基础和工作方法--马克思主义理论和唯物辩证法作为理论支撑,通过对国内外现状的研究和国外先进经验的借鉴,分析出我国高校德育工作存在的问题及原因,进而构建了新形势下提高高校德育工作实效性的对策构想,形成了一个集明确德育目标、丰富德育内容、加强课程设置、拓展工作途径、创新工作方法、加强队伍建设于一体的高校德育工作优化体系。

German philosopher whose idealistic system of metaphysics was highly influential; it was based on a concept of the world as a single organism developing by its own inner logic through trios of stages called "thesis, antithesis, and synthesis" and gradually coming to embody reason.

德国哲学家,其理想化系统的形而上学,是很有影响力的,它是基于对概念的世界作为一个单一的有机体,发展自己的内在逻辑,通过trios的阶段,所谓的&论文,对偶,与合成&,并逐步来体现的原因。

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For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降,而后引起了信用卡大规模的亏损。

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弗四23 而在你们心思的灵里得以更新

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