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They have segmented with two or three distinct parts, and jointed appendages on the segments.

它们被分成两个或三个明显的体部,并连接体节的附肢。

Yeah, sorry about that. But, the silver lining is Corpus Christi should be clear and warm and, hey, it's bikini season!

不好意思。但是,万幸的是圣体节的天气应该是晴朗暖和的,现在可是看比基尼美眉的季节啊!

On the other hand, in spite of the severely distorted axis, the FoxD5-overexpressed embryos displayed neither somite nor muscle defects. Based on these results, we speculate that FoxD5 plays different roles in axis and somite formation. During somitogenesis, FoxD5 functions in the maintenance of the anteroposterior polarity of somites, and in turn plays roles in proper formation of somites.

另一方面,观察过量表现FoxD5的胚胎,发现体节及肌肉发育没有明显异常,但体轴发育则产生严重畸形的性状;根据上述观察结果,推测FoxD5可能在体节及体轴发育上扮演不同角色:在体轴发育时,FoxD5则可能参与於胚胎轴向决定;而在体节中,FoxD5具有维持体节前后极性进而促使体节正常形成之功能。

Undifferentiated tissue from which new cells are formed, as at the tip of a stem or root meristematic

分节的,分成体节的 meritn。功绩,价值,真相

During somitogenesis, zebrafish FoxD3 is known of maintaining the somitic expression of myf5, and subsequently regulates myogenesis. FoxD5, another gene of the FoxD family, is also expressed in forming somites of the anterior PSM. However, the regulatory function of FoxD5 in somitogenesis is not clear.

虽然已知斑马鱼中FoxD3在体节发育时,能维持myf5在体节的表现并藉此参与於肌肉的发育;但FoxD转录因子家族中的另一员,FoxD5,在体节发育时也会表现在presomitic mesoderm前端生成中的体节处,而这个FoxD转录因子是否在体节发育的过程中扮演调控的角色目前仍不清楚。

The condition of having the body divided into metameres, exhibited in most animals only in the early embryonic stages of development.

位变异构身体被分成一系列相同体节的状况,在大多数动物中仅存于胚胎发育的早期阶段

During the past three decades, several models have been proposed to explain the formation of somites, including the clock and wavefront model, the reaction-diffusion type model, the clock and induction model, the clock and trail model, and others.

近30年来,研究者们就体节的发生和分化提出了多种解释模型,这包括时钟波峰模型、反应扩散模型、时钟诱导模型、时钟痕迹模型等,这些模型从不同角度不同程度解释了动物体节发生和分化的不同现象。

During the last three decades, several models have been proposed to explain the formation of somites, including the clock and wavefront model, the reaction-diffusion type model, clock and induction model, clock and trail model etc. Although some of them are satisfactory in the different aspects of somitogenesis, no one can explain the formation and regulation of somites perfectly.

近三十年来,研究者们就体节的发生和发育提出了多种解释模型,这包括时钟波阵面模型,反应扩散模型,时钟诱导模型,时钟痕迹模型等,虽然这些模型能从不同角度不同程度来解释动物体节发生和发育的不同现象,但无一能够解释体节发生和发育的全部。

With the development of embryo, Myf5 expression decreased gradually in somites in the anterior region, but remained strong in the newly formed somites; After 30 somites formed, MyoD expression decreased in the somites except the caudal somites. At the hatching stage, MyoD and Myf5 were expressed in head muscle cells and fin muscle cells. In the growing fish, Myf5 was expressed in the skeletal muscle and intestine, and in adult flounder, Myf5 was only expressed in muscle. In the growing fish and adult fish, MyoD was only expressed in muscle.

在胚胎发育早期,Myf5在近轴中胚层中表达,体节发生过程中,Myf5在体节中表达,MyoD基因最早在分节板的体节前细胞中表达,随后在近轴细胞、体节中表达;随着胚胎的发育,Myf5在成熟体节中表达量降低,在新生体节中表达较强;MyoD自30个体节时期后只在新生的尾部体节中表达,在成熟的体节中表达量降低;在孵化期,MyoD和Myf5在头部及鳍的肌肉、尾部的体节中表达;生长期的牙鲆中,Myf5在骨骼肌和肠中表达,成体牙鲆中,Myf5只在肌肉中表达;生长期的牙鲆及成体牙鲆中,MyoD只在肌肉组织中表达。

Furthermore, myogenesis was not affected in the FoxD5 morphants, owing to the results of myf5 downergulation in somites and myod upregulation due to the knockdown of myf5, and therefore resulted in myogenin normal expression. In addition, FoxD5 was upregulated in the FoxD3-knockdown embryos, suggesting that FoxD5 might compensate the functions of FoxD3 in the PSM.

进一步观察体节后期分化之肌肉发育,发现在FoxD5 morphants中虽然myf5在体节的表现下降却由表现上升的myod所补偿,因而使得myogenin的表现没有发生变化,显示FoxD5 morphants之肌肉发育没有受到影响;而观察抑制FoxD3的胚胎中,FoxD5在新生成体节中会有表现异位的表现,显示FoxD3在PSM之功能可能由FoxD5来补充。

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