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Segmental bone defects of 20 percent right tibia middle and inferior diaphysis of the 24 goats were made.

材料:山羊24只,体质量(22.5±2.5)kg,右侧胫骨中下段截除胫骨总长度20%形成节段性骨缺损。

Lesion was made by current of 1mA, 210s in the dorsal funiculus at the 10th thoracic vertebral level. Behavioral and histological evaluation, HRP and fast blue retrograde labelling method were employed. The eletrolytic current caused bilateral corticospinal tract injury and incomplete paraplegia in hind limbs, and led to a substantial atrophy of corticospinal motoneurons , serving as a reproducible and practical model for research on SCI.

在大鼠T10胸椎节段脊髓后索插入损毁电极,通电1mA,210s,应用行为学评分、脊髓局部组织学检查、HRP和荧光逆行示踪方法发现,电解损伤造成了双侧皮质脊髓束纤维受损,大鼠双侧后肢肌力下降、肌张力升高、运动功能下降,同时大脑运动皮层处皮质脊髓束胞体发生明显逆行性萎缩,可作为一个稳定、可靠的SCI模型。

This experiment showed that there was an proliferative changing at the cell of nodose ganglion of the sensory nerve fiber in lung when asthma attacked and suggested that the changing of growth and excitability of lung sensory nerve may well result from the change of neuron.

本实验表明哮喘时肺内感觉神经纤维的胞体所在部位颈静脉节的细胞也发生了增生性改变,提示肺内感觉神经纤维的生长和兴奋性变化可能是源于神经元胞体的变化。

Egg capsule showed no clear boundary and contained only one egg. However, the scolex and suckers of R. tetragona were oval in shape, and the neck was long and thin. The ovary was flower-like. Each egg capsule contained 4-12 eggs and many calcareous corpuscles, each of which was surrounded by a membrane.

四角瑞利绦虫链体相对较长,头节及吸盘均呈椭圆形,颈部尤为细长;卵巢呈花朵样分瓣,卵黄腺呈豆状,卵囊周围有明显的囊壁,卵囊内含有4~12个数目不等的虫卵及大量成团的细小折光性颗粒。

The renal specimen biopsy demonstrated focal necrotizing and crescentic glomerulonephritis.

肾活检可见小血管壁节段性纤维素样坏死,新月体多见。

Cases healthy subjects served as control. In addition, density of glomerular matrix membrane and quantity of cell in glomeruli were measured with CMIAS image analysis system by computer. Global sclerosis, cellular crescents, fiber or fibrocellular crescents were measured with Memphis scope. Tubulointerstitial lesions were examined with semi-quantitative grades (including O-III grades).Results Compared to normal control, there was a significant increase of urinary TGF-betaK IL-6 and Col-lV levels in patients with IgAN (p. 01). There were also significantly positive correlation between the levels of urinary TGF-betaK Col-IV and density of glomerular matrix membrane ., interstitial fibrosisp.

采用酶联免疫吸附法测定尿TGF-β1(Transforming growth factor-β1)、尿IL-6(interleukin-6)和尿Col-Ⅳ(type Ⅳ Collagen);采用免疫组织化学法检测肾组织TGF-β1、Col-Ⅳ表达;应用CMIAS多功能真彩色病理图像分析系统对肾小球基质基底膜面密度和细胞个数进行半定量测定;对球性硬化、节段硬化、细胞新月体及纤维或纤维细胞新月体所占肾小球百分数和肾小球IgA沉积免疫荧光强弱的判断采用Memphis法进行评分;肾小管间质病变程度采用光镜下半定量分级法(包括0-Ⅲ级)。

The attenuation values at unenhanced and enhanced CT of the tumor were also recorded. Results The 32 cases adrenal neoplasms included 9 cases with aldosterone-producing adenoma, 5 hydrocortisone-producing adenomas, 1non-functional adenoma, 5 cortical hyperplasies,4 pheochromocytomas,2 adenocarcinomas, 3 metastases, 1 fibroneuroma, 1 ganglioneuroma and 1 myelolipomas. Conclusion The characteristics on CT images are associated with the pathological feature in adrenal neoplasms.

结果 醛固酮腺瘤9例,体积较小且密度低,增强后轻度增强;皮质醇腺瘤5例,瘤体较大,边界清,密度略低于正常肾上腺组织;无功腺瘤1例;结节增生5例,为等或稍低密度影,增强后强化较明显;嗜铬细胞瘤4例,体积较大,密度不均,可见多个囊变坏死区;皮质腺癌2例,肿块形态不规则,边缘模糊,密度不均匀,易发生大片坏死及点状钙化;转移瘤3例;神经纤维瘤、神经节瘤及髓性脂肪瘤各1例。

Results According the MRI characteristric of hypoxic-ischemic encephalopath sequela:(1)The most common findings were white matter injury in 47 cases:①Periventricular leukomalacia in 23 cases;②Selective cerebral neuronal necrosis of basilar node lentiform nucleus and optic colliculus in 9 cases;③Corpus callosum damaged in 15 cases;(2)The most damaged of grey matter in 18 cases;(3)Focal or multifocal ischemic crerbral intenerate in 9 cases;(4)Diffuse crerbral injury in 5 cases.

结果 根据儿童缺血缺氧性脑病后遗症的MRI影像特点,将其分为:(1)脑白质损伤为主:47例;①脑室周围脑白质脱髓鞘、软化:23例;②基底节豆状核、视丘神经元选择性损害:9例;③胼胝体受损变薄:15例;(2)脑灰质损害为主:18例;(3)局部或多处脑软化:9例;(4)广泛脑损害:5例。

Results According the MRI characteristric of hypoxic\|ischemic encephalopath sequela:(1)The most common findings were white matter injury in 47 cases:①Periventricular leukomalacia in 23 cases;②Selective cerebral neuronal necrosis of basilar node lentiform nucleus and optic colliculus in 9 case...

结果 根据儿童缺血缺氧性脑病后遗症的MRI影像特点,将其分为:(1)脑白质损伤为主:47 例;①脑室周围脑白质脱髓鞘、软化:23 例;②基底节豆状核、视丘神经元选择性损害:9 例;③胼胝体受损变薄:15 例;(2)脑灰质损害为主:18 例;(3)局部或多处脑软化:9 例;(4)广泛脑损害:5 例。

The authors sug-gest that the decreased density of BDNF positive products in lamina II on the 3rd and 6th day was related with the degenerationof the nerve fibers and varicosities after section of the adjacent dorsal roots. On the 12th day, the remaining L6 dorsal roots un-derwent collateral sprouting compensatoryly and reestablished functional connection with target neurons.

作者认为3 d、6 d的减少主要与邻近背根节切除后,其神经纤维和膨体溃变有关;12 d时,保留的Ls背根逐渐侧支出芽,且与靶细胞再建功能联系,故脑源性神经营养因子阳性神经纤维和膨体数均趋于恢复。

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