体腔上皮

Objective To study the toxic effect of body fluid of Ascaris lumbricoides on human intestinal epithelial cells (HCT-8 cells) and how the ABF concentration and inducing time could be related to the toxicity.

目的 探讨人蛔虫体腔液(Ascaris body fluid， ABF)对人肠上皮细胞株(HCT-8)的毒性作用及作用浓度和时间的关系。

Objective: To investigate, 1 whether the body fluid of Ascaris lumbricoides could induce apoptosis of human alveolar epithelial cells (A549 cells) in vitro, and if there would be a possible relationship of ABF concentration or inducing time with the extent of apoptosis; 2 if the expression of bcl-2/bax would involve in and how it changes during the inducement of the apoptosis of A549 cells.

目的：用人蛔虫体腔液(Ascaris body fluid，简称ABF)体外诱导人肺上皮细胞株(A549)，观察其是否能够诱导靶细胞凋亡及凋亡与ABF浓度和作用时间的相互关系；运用RT-PCR方法检测靶细胞诱导过程中bcl-2／bax基因的表达变化，探讨其凋亡与基因表达的相互关系。

Epidermal cells near the wound dedifferentiate and proliferate forming blastema and/or migrate to the wound plane forming a pre-epidermis consisting of several layers of stem cells covering the wound plane, which then re-differentiates further forming fully developed epidermis. Cells in the parietal peritoneum are also induced by injury to dedifferentiate into stem cells which then proliferate and migrate along the parietal peritoneum to the wound place forming a pre-peritoneum which re-differentiates into fully developed parietal peritoneum.

伤口愈合包括伤口闭合、顶端表皮层及体腔上皮的新生：创伤后的前4 d，残腕顶端的肌肉组织向伤口处迁移并重排使伤口闭合；创伤附近的表皮层细胞发生脱分化并增殖后迁移到创伤面形成由数层干细胞组成的前表皮层，之后进一步分化形成表皮层；而体腔上皮细胞在创伤诱导下也脱分化并增殖，然后沿体腔上皮迁移到创伤处形成"前体腔上皮"，经再分化形成新的体腔上皮。

About 4 days post amputation, cells in some areas in the out epidermis and inner parietal peritoneum near the end of the stump are induced by injury to dedifferentiate into stem cells and then proliferate forming stem-cell masses, which then invaginate into the interior dermis. The dermal cells are then induced by those invaginating stem-cell masses to dedifferentiate.

从第4 d起，近创伤处的表皮层和体腔上皮中部分细胞发生了脱分化形成了干细胞，并增殖形成了干细胞团，然后向真皮层内陷，并诱导真皮层组织发生脱分化，最终在残腕体壁的不同部位形成了众多干细胞原基，是进一步再生所需的细胞库。

After amputation, the expression of desmin appears first in the distal end epidermis and the peritoneum 4 d PA. The expression in the peritoneum lasts to the 14 d PA when expression of desmin appears in the musculature, while that in the distal end epidermis only lasts to the 8 d PA when the connective tissue below begins to express desmin. Moreover, from the 4 d PA, musculature and epidermis of the tube foot begin to express desmin and the expressions last to the 20 d PA. From 8-14 d PA, musculature of the ambulacral plate expresses myogenin and the peritoneum also expresses myogenin from 14-20 d PA. All these results indicate that precursor cells for muscle regeneration in adult starfish A.rollestoni are mainly from the distal end epidermis and the parietal peritoneum.

创伤后第4 d，顶端表皮层及体腔上皮中首先出现了desmin表达，体腔上皮中desmin的表达一直持续到第14 d，此时其上方的肌肉组织中也出现了desmin表达；而顶端表皮层中desmin的表达仅持续到第8 d，同时其下方的结缔组织也开始表达desmin；此外，从第4 d起，管足肌肉及管足表皮层开始表达myogenin，且该表达一直持续到创伤后的第20 d；而第8 d起，步带板肌肉也出现了myogenin的表达，此表达一直持续到第14 d；从第14 d起，体腔上皮也出现myogenin表达，且一直持续到第20 d。

Although it is widely believed that ovarian epithelial tumours arise in the coelomic epithelium that covers the ovarian surface, it has been suggested that they could instead arise from tissues that are embryologically derived from the Mullerian ducts.

虽然普遍认为卵巢上皮性肿瘤出现在覆盖卵巢表面的体腔上皮，有研究提示它也可以出现在胚胎学上来自苗勒管的组织。

The CA125 is an epitope on a large mucin glycoprotein molecule of greater than 1 million Daltons,normal expressed on the coelomic epithelium,including ovarian surface.By now,CA125 assay has been used for monitoring response to primary treatment,detecting clinically occult ovarian cancer at the time of recurrence,as well detecting primary disease in early stage.The CA125 level is abnormal in over 90%of advanced stage ovarian cancer,but it is not increased in about 50%of the patients with stageⅠdisease.

卵巢癌肿瘤标记物中最常用的是CA125，它是体腔上皮正常表达的一种抗原蛋白，晚期卵巢癌中，超过90%病例CA125升高，而在Ⅰ期卵巢癌中，大约有50%病例CA125正常，因此血清CA125敏感性和特异性不能满足筛查指标的要求。

Epidermal cells near the wound dedifferentiate and proliferate forming blastema and/or migrate to the wound plane forming a pre-epidermis consisting of several layers of stem cells covering the wound plane, which then re-differentiates further forming fully developed epidermis. Cells in the parietal peritoneum are also induced by injury to dedifferentiate into stem cells which then proliferate and migrate along the parietal peritoneum to the wound place forming a pre-peritoneum which re-differentiates into fully developed parietal peritoneum.

伤口愈合包括伤口闭合、顶端表皮层及体腔上皮的新生：创伤后的前4 d，残腕顶端的肌肉组织向伤口处迁移并重排使伤口闭合；创伤附近的表皮层细胞发生脱分化并增殖后迁移到创伤面形成由数层干细胞组成的前表皮层，之后进一步分化形成表皮层；而体腔上皮细胞在创伤诱导下也脱分化并增殖，然后沿体腔上皮迁移到创伤处形成&前体腔上皮&，经再分化形成新的体腔上皮。

The layer of flat cells of mesodermal origin that lines the embryonic body cavity and gives rise to the squamous cells of the peritoneum, pericardium, and pleura .

间皮起源于中胚层的扁平细胞层，衬于胚胎的原始体腔中，最终发育成腹膜、心包及胸膜的上皮细胞

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。