低

The expression of p-p38 and Rho GDIαwas upregulated in LCA by either low shear stress or hypertension. However, the highest expression of p-p38 and Rho GDIαwas observed in LCA of low shear stress accompanied by hypertension.(4) Effect of low shear stress on both decreasing apoptosis and increasing proliferation of VSMCs in LCA was reversed by tributyrin, a HDAC inhibitor.

当高血压伴有低切应力时，两者的协同作用诱导p-Akt的表达水平进一步增加；(3)高血压和低切应力都可以诱导颈总动脉p38和Rho GDIα表达增加；当高血压伴有低切应力时，两者的协同作用诱导颈总动脉p38和Rho GDIα表达进一步增加；(4)HDAC抑制剂Tributyrin可以通过抑制VSMCs增殖，促进VSMCs凋亡，在干预低切应力诱导的血管重建中发挥作用。

At the super-low permeable reservior sandstone of Fu and Yang in Daqing Oilfield, many pore throats exist a lot in the types of compacted and restored flakes and curved lamellas while the pore volume of micropore and the thin, compacted and shrunken throat that contribute little to flow take large scale in the total pore space. Thereof high filtrational resistance is caused by much trouble including high content of reservoir shale, serious sensibility to pressure at waterflooding, remarkable effects of undersaturation and water blocks in micropore. A method with laboratory experiment, theoretical confirmation and field application included was adopted to analyze the non-linear flow characteristics, to reveal the deep mechanism of pinhole enveloping macropore and to provide a new technology of improving the development effect. The outcomes aquired are as follows: Multiple cores with different low and super-low permeability were selected to perform seepage experiments by gas, water and oil. Three fields of flow were observed in the reservoir at different low and super-low core permeability. They are pseudo- elastic flow, transition flow and plastic creep flow. So the concept that there was no correlation of rocky absolute permeability with fluid properties that pasted itself was broken up. Two-phase seepage of water displacing oil in uniform super-low permeability shows that the two-phase seepage zone is narrow.

针对大庆油田扶、杨特低渗透油层砂岩孔隙喉道的大小和形态以压实再生型片状、弯片状喉道分布较广，压实、缩小型细喉道型，微孔不可流动的孔隙体积所占总孔隙体积的比例较大的特点；及储层泥质含量高，注水开发中压力敏感性强、微孔隙欠饱和及水锁效应显著，导致流体渗流阻力增大的问题，本文采用室内实验、理论推证和矿场应用相结合的方法，研究、分析了流体非线性渗流特征，更深刻地揭示出小孔包围大孔的机理及产生原因，并提供了改善开发效果的新的技术方法，取得如下成果：选择不同渗透率的低渗透、特低渗透岩心，进行了气、水和油单相渗流实验，揭示出当岩心渗透率不同时，油层内的流体呈现出拟弹性流变、过渡流变、塑性蠕变三种流变区，从而打破了岩心的绝对渗透率与通过岩心流体性质无关的观点；同类特低渗透岩心的水驱油两相渗流实验表明，两相渗流区较窄。

According to permeability, associating with pore type, pore throat radium, ratio of pore throat radium, and connectivity of pore throat, the reservoir is divided into two groups: moderate permeability reservoir with moderate pore and small throat and low permeability reservoir. the latter is further classified into three types: moderate pore and small throat reservoir, small pore and unhomogeneous and subtle throat reservoir, and small pore and homogeneous and subtle throat reservoir.

在此基础上，以渗透率为主线，结合孔隙类型、孔喉半径、孔喉半径比以及孔喉连通性等参数，将研究区储层主要划分为中渗透储层和低渗透储层2种基本类型，前者以中渗透中孔细喉道型为主，后者又进一步细分为低渗透中孔细喉道型、低渗透小孔不均匀微细喉道型和低渗透小孔较均匀微细喉道型等3个亚类。

In comparison with F-A and F-B, low molecular weight fucoidan fractions had little lower proportions of sulfate, but similar proportions of uronic acid.

结果表明，大分子和低硫低分子量的组分对02·一、·OH和HOCI有很好的清除作用，而高硫低分子量的组分的活性非常低。

The results of the effect on HSV-2 virulence experiment and the sample-canceling experiment showed that the four sulfated oligosaccharides had no virucidal activity to HSV-2 but inhibition activity.

初步探讨了低聚糖硫酸酯的抗病毒作用机制，由不同时间加药实验结果推测四种低聚糖硫酸酯具有类似的作用机制，可能作用于HSV-2与细胞的吸附阶段，不能抑制病毒在细胞内的复制过程；低聚糖硫酸酯的作用对象为病毒；对病毒毒力的影响实验和撤药实验说明四种低聚糖硫酸酯不能杀灭HSV-2，仅起抑制作用。

In the stimulation of grave hypoxia reach to one extent,Gansu zokor may impellingly smooth launch of its own mechanism to hypoxia from molecular, cellular and structure level to the overall coordination,and not to appeared heart failure. Gansu zokor will remain survival at the hypoxic conditions with the stability in cardiac muscle structure and its nomal function.

综上所述，本研究结果说明甘肃鼢鼠虽长期生活在地下低氧环境中，但对严重的低氧环境仍比较敏感，在一定程度的严重低氧刺激下才会迫使其顺利启动其自身从分子、细胞水平到整体协调的低氧耐受机制，使心脏不至出现衰竭的现象，从而在心肌组织结构稳定的情况下，发挥正常功能，维持在低氧条件下的生存。

The combined acids , LHZZS,XDZZS and SLZZS, one of four fractions in montan resins from montan waxes from Liaohu, Xundian and Shulan brown coal respectively, were derived by CH 2N 2 to methyl esters and their chemical constituents and structural characteristic were studied on GC-MS.

结果显示，树脂结合酸均以正构烷酸为主要成份，其分布为C1 2 ～C2 8，高含量的正构烷酸集中在低碳数一端，C2 0 含量最高，其次为C1 6 ，而舒兰结合酸中，正构烷酸占绝对优势，且C1 6 为最高含量的化合物；去氢松香酸在每一个样品中含量较低，其它三环二萜酸，如松脂酸、三达松脂酸等异构体或立体异构体含量也非常低；具有五环三萜骨架的酸性物质，在潦浒、舒兰结合酸中比较丰富，其含量超过寻甸结合酸；在低碳数一端，存在着各种支链烷酸及苯甲酸、苯酚及取代物。

Comparing with marine oils in the adjacent areas, all crude oils in Hade 4 oil field (except for HD401 well) have following peculiarity: very similar in the composition of light hydrocarbon fraction, and the distribution of of phytane-series isoprenoid alkanes, high concentration in steranes, terpanes and their aromatized compounds, as well as rearranged steranes; low concentration of gammacerane, 24-norcholestanes and 24-rearranged steranes, and low C〓 regular steranes C〓/(C〓+C〓+C〓＜20%; 3-methyl steranes and 27-norcholestane predominated, respectively; very low concentration of dinosterane and 4-methyl steroid.

分析表明，与相邻地区海相原油比较，除最南端的HD401井原油外，其它井区原油均具有下述特点：轻烃馏分组成十分接近、植烷系列类异戊烯烷烃分布较为一致、甾萜类和芳香甾萜类环状化合物浓度较高、重排甾烷丰度较高、伽马蜡烷含量低、规则甾烷组成中C〓丰度低C〓/(C〓+C〓+C〓＜20％、甲基甾烷中以3-甲基甾烷为主、甲藻甾烷和4-甲基甾烷丰度极低、降胆甾烷中以27-降胆甾烷为主、24-降胆甾烷和24-重排降胆甾烷丰度低。

Experiment studied the possibility of substituting Portland cement for alumina cement to make low cement castable refactory. The results indicated that Portland cement may definitely substitute the alumina cement to make low cement castable with good performance, within the scope of low cement content of the modern low cement castable system.

试验研究了硅酸盐水泥替代矾土水泥制造低水泥耐火浇注料的可能性，结果表明在低水泥掺量的现代低水泥耐火浇注料体系中，硅酸盐水泥完全可以替代矾土水泥配制性能良好的低水泥耐火浇注料。

The results confirm that NH3 slip increases with both higher ratio of NH3 to NO n(NH3/n and higher concentration of a reducing reagent, while it decreases with the increase of temperature. Initial NO concentration and its residence time can also affect the NH3 slip. A higher initial NO concentration lead to higher NH3 slip, but added residence time has the opposite effect. Among urea, ammonium carbonate and ammonia liquor, the NH3 slip of urea is the highest and that of ammonia liquor is the lowest.

试验结果表明：温度越高，漏失氨含量越低；随氨氮物质的量比的增加，NH3漏失含量不断增加；还原剂质量浓度越低，NH3漏失含量越低； NO初始浓度和停留时间对漏失氨浓度也有影响，NO初始浓度越高NH3漏失浓度越高，停留时间越长漏失氨浓度越低；不同还原剂NH3漏失浓度不同，尿素、碳酸氨、氨水3种还原剂中，尿素的NH3漏失浓度最高，氨水的NH3漏失浓度最低。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐