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Methods Fifty pairs of fresh colorectal cancer and homologous normal tissues were genotyped with Identifiler Kit and the mutations generated in cancer tissues were determined. The mutation rates, the numbers of locus matched without identical allele (A0), 1 identical allele (A1), or 2 identical alleles (A2) and the number of total identical alleles IA(subscript n were calculated. Frequency distributions of A0, A1, A2 and IA were compared among CR-N group, unrelated individual pairs and full sibling pairs. Discrimination functions were established for individual identification from tumor tissues with discriminatory analysis.

用Identifiler系统对50对新鲜结直肠癌组织及其身源正常组织组进行STR分型,计算CR-N组中变异STR基因座及全不同基因座数(A0)、半相同基因座数(A1)、全相同基因座数(A2)和共有等位基因数IA(下标 n,比较CR-N组、无关个体对组和全同胞对组中上述参数的分布差异,通过判别分析建立判别函数。

The types of histone methyltransferases, the relationship between methylation of Lysine 9 of H3 and the formation of heterochromatin, gene regulation in euchromatin, and that with DNA methylation, were mainly introduced.

主要阐述了组蛋白甲基转移酶的类型,组蛋白H3中第9位赖氨酸甲基化与异染色质的形成、常染色体中基因表达的调控,以及与DNA甲基化之间的关系,说明了组蛋白甲基化与组蛋白乙酰化、磷酸化的相互关系,指出组蛋白甲基化对维持细胞各种状态的平衡起到极其重要的作用。

Methods: The parameters of patellofemoral joints (normal group: 30; abnormal group: 20) were studied at the 0, 6, 12, 18, 24, 30 and 36 degrees of flection with MR in axial plane and MPW, LPA, FTA, PTA, FTD were measured, then, compared in the normal and abnormal ups.

对两组(正常组30个,病例组20个)膝关节分别在被动屈曲0,6,12,18,24,30,36下进行轴位动态MRI检查,测量髌骨最大径,外侧髌股角,股骨滑车沟角,髌骨倾斜角,股骨滑车沟深度,分别比较正常组及病例组在七个不同屈曲角度下各测量参数的差异性。

Appraised the "Blood-Stasis" clinical appearance integrative scores, Nail fold Microcirculation scores, and determined hemorheological indexes before and after treated 3 months, 6months, then contrast intragroup and intergroup, and contrast to 30 healthy mid-age women who underwent checkup at the same time; determined anterior-posterior position lumbar1~4 vertebra body bone mineral density before and after treated 6 months, then contrast intragroup and intergroup.

两组治疗前及治疗3个月、6个月后分别评定"血瘀"临床表现综合评分、甲襞微循环评分并测定血液流变学指标,组间及组内治疗前后对比,并分别与同期体检30例健康中年妇女对比;治疗前及治疗6个月后测定腰1-4椎体前后位骨矿物密度,组间及组内治疗前后对比。

This text hold with pair liquid location production process control system for the background , use the configuration software to structure the control system of a long time, the content includes: Have carried on more overall exposition to the development and basic composition , the characteristic and configuration software system structure of the configuration software of the configuration software at first, through analysing , have affirmed the configuration software as the meaning of control system programming tool of the production process.

本文以双容液位生产过程控制系统为背景,应用组态软件构建一个过程控制系统,内容包括:首先对组态软件的发展和组态软件的基本组成、特点及组态软件体系结构进行了较全面的阐述,通过分析,肯定了组态软件作为生产过程控制系统编程工具的意义。

Results: Neonatal rats in hypoxic-ischemicgroup behaved restlessness, cyanosis, deep and rapid breath, astasia, lethargy, irritation and spasm; There were local pyknosis, fragmentation, dissymmetry, blur or disappearance of nucleoli, raritas of ground substance in left cerebral cortex; but there was no statistic significance in chinese traditional medicine group and sham group. The expression of HIF-1α mRNA in brain tissue of experimental group and chinese traditional medicine group were higher than that in sham group, especially chinese traditional medicine group at 3d; HIF-1α positive cells were found in cerebral cortex and hippocampus. There were more HIF-1α positive cells in experimental group and chinese traditional medicine group and mainly in vascular endothelial cells.

结果 缺氧缺血后大鼠相继表现为烦躁不安、全身发给、呼吸加深加快、站立不稳、嗜睡、激惹或间断发作的痉挛和抽搐;HE染色显示实验组大鼠左侧大脑皮层出现局灶性神经元核固缩,核碎裂,核仁偏位,不清或消失,基质疏松;中药组大鼠脑组织结构基本接近假手术组,无明显水肿和坏死表现;实验组和中药组大鼠脑组织HIF-1α mRNA表达较假手术组明显增加,尤其是中药组实验第3日者;免疫组化显示实验组和中药组各时间点大鼠大脑皮层和海马区均可见不同程度的HIF-1α表达,明显高于假手术组,阳性表达主要在血管内皮细胞,海马和皮层的锥体细胞亦有HIF-1α阳性细胞分布。

Results: Two groups 64 sides joint equally to obtain limpid MR image, on oblique sagittal of close mouth T1 and PDW images showed that the anterior disc border in TMJ ID people was sited around 0.42mm, before the vertical line of the lower end of articular eminence,while it is sited 0.14 mm,before the vertical line in normals, There exists significant statistical difference. The junction of posterior band of the disc and the bilaminar region in TMJ ID people was sited at 14.4°of vertical line of condile center,but in normals it was 3.18°There exists significant statistical difference.

结果: 两组64侧关节均获得清晰的MR图像,T1WI和PDWI图像斜矢状闭口位时,在TMJ ID组关节盘前缘位于关节结节最低点垂直线前约0.42 mm,而正常对照组则位于其前约0.14 mm,两组间差异有统计学意义,在TMJ ID组关节盘后带与双板区交界处约位于髁状突12点位垂直线14.4°处,而正常对照组则位于其3.19°处,两组间差异有统计学意义。

In this observational study, 65 children were treated with SLIT with a build-up phase of 11 days, culminating in a peak dose of 300 IR, and followed by a maintenance phase of 300 IR three times weekly. There were 51 boys and 14 girls; age range was 38 to 80 months (median age, 60 months). Allergens used were house dust mites in 42 patients, grass pollen in 11, olive pollen in five, Parietaria pollen in four, and cypress pollen in three patients. Adverse reactions and changes in the treatment schedule were compared in children aged 38 to 60 months vs those aged 61 to 80 months.

在这项观察性试验中,65位接受SLIT的儿童在11天的适应期后,将剂量逐渐调整到最高300 IR,接著以每周3次,每次300 IR的剂量持续接受治疗;试验中包括51位男童与14位女孩,年龄介于38至80个月(平均年龄为60个月);其中有42位病患以尘蹒、11位以花粉、5位以橄榄花粉、4位以墙草、3位以丝柏作为过敏原;年龄介于38至60个月的儿童,与61至80个月的儿童分成两组比较不良反应发生机率与治疗疗程的改变。

In this observational study, 65 children were treated with SLIT with a build-up phase of 11 days, culminating in a peak dose of 300 IR, and followed by a maintenance phase of 300 IR three times weekly. There were 51 boys and 14 girls; age range was 38 to 80 months (median age, 60 months). Allergens used were house dust mites in 42 patients, grass pollen in 11, olive pollen in five, Parietaria pollen in four, and cypress pollen in three patients. Adverse reactions and changes in the treatment schedule were compared in children aged 38 to 60 months vs those aged 61 to 80 months.

在这项观察性试验中,65位接受SLIT的儿童在11天的适应期后,将剂量逐渐调整到最高300 IR,接著以每周3次,每次300 IR的剂量持续接受治疗;试验中包括51位男童与14位女孩,年龄介於38至80个月(平均年龄为60个月);其中有42位病患以尘蹒、11位以花粉、5位以橄榄花粉、4位以墙草、3位以丝柏作为过敏原;年龄介於38至60个月的儿童,与61至80个月的儿童分成两组比较不良反应发生机率与治疗疗程的改变。

Interlayer oxidized zone can be divided accurately by Fe_2O_3, Fe_2O_3/FeO and U parameters. We can correct the field macroscopic color zoning by combining the macroscopic zoning and microscopic zoning. Univalent major elements components(Al_2O_3, SiO_2, K_2O, Na_2O) show remarkable activity at the process of interlayer oxidizing, their contents are variable and mingled in different zones and it can't be used in zoning. But we can speculate the developmental degree of interlayer oxidized zone and uranium mineralization according to the concentration trends and variation characteristics of sensitivity group, activity group and their ratios .(3)The comparatively steady elements such as lithiphile elements, sulfophile elements and high field strength elements change regularly at the process of interlayer oxidation except some radioactive elements. Trace elements and rare earth elements commonly enrich in thin rock clast such as mudstone, in which the enriched elements species are more than those in the whole rock, which indicate that the regeneration action in caulking matter are more deep than that in whole rock at the process of interlayer oxidation, and the reallocate intention of trace elements in main minerlized rock in Tuha basin are more intensive than that in Yili basin at the process of deposition ,diagenesis and later changes .

根据化学蚀变参数PC值和分离迁移位等将常量元素组分分为敏感组分组、活动组分组、次活动组分组和惰性组分组,不同组分可分别用于讨论层间氧化带低温地球化学中不同问题;敏感组分(变价元素组分Fe_2O_3、FeO)和U在层间氧化带中迁移富集规律明显,Fe_2O_3/FeOFe~(3+/Fe~(2+)比值具分带判别能力,配合U含量对层间氧化带进行较准确的分带,可克服野外宏观颜色分带偏差:提出Fe~(3+)/Fe~(2+)分带判别值在不同盆地、不同地段不同,除受氧化作用控制外,流体酸碱度不同也是重要因素的观点,对找矿实践有实际指导意义;活动组分(Al_2O_3、SiO_2、K_2O、Na_2O)在层间氧化作用过程中具有较明显的活动性,其含量值变化跳跃,在不同分带相互交织,不具分带指示意义;但利用敏感组分、活动组分及其比值在层间氧化带中的变化特征可推测层间氧化带发育的完善程度及其含矿性;次活动组分组(CaO、MgO、MnO_2)含量低,变化规律性差;惰性组分组(TiO_2、P_2O_5)含量低,活动稳定,可用来反映沉积物源特征。

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