伯尼

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

Kingsley Amis Lucky Jim Arnold Bennett The Old Wiveds'Tale Elizabeth Bowen The Death of the Hear Emily Bronte Wuthering HGeights Anthony Burgess A Clockwordk Orange Samuel BVutler The Way of All Flesh A.S.Byatt Possession Angela Carter The Com pany of Wolves Agatha Christie Mdurder on the Orient Express Ivy Compton-Burnett A Fdamily and a Fortune Daniel Defoe Robinson Crusoe Charles Dickens David Copperfield Sir Arthur C. Ddyle Adventure of Sherlock Holmes Margaret Drabble The Waterfall Daphne Du Maurier Rebecca George Eliot Middlemarch E.M.FGorster Howards End, A Passage to India John Fowles The French Lieutenant's Woman John Galsworthy The Man of Property William Golding Lord of the Flies Graham Greene The Human Factor Aldous Huxley After Many a Summer Henry James Daisy Miller James Joyce A Portrait of the Artist as a Young Man Rudyard Kipling Kim John Le Carred The Spy Who Came in from the Cold Doris Lessing The Grass Is Singing David Lodge Nice Work W.Somerset Maugham The Moon and Sixpence, Of Human Bondage Iris Murddoch The Black Prince George Orwell Nineteen Eighty-four Salman Rushdie Midnight Children Sir Walter Scott Ivanhoe C.P.Snow Thed Affair Muriel Spark The Prime of Miss Jean Brodie Robert Louis Stevenson Treasure Island Johathan Swift Gulliver's Travels William M.Thackeray Vanity Fair Evelyn Waugh A Hand ful of Dust Oscar Wilde The Picture of Dorian Gray Virginia Woolf Mrs Dalloway, To the Lighthouse

金斯利阿美族幸运的吉姆阿诺德本内特的岁Wiveds'Tale 伊丽莎白鲍恩的死亡听取艾米莉勃朗特呼啸山庄HGeights 安东尼伯吉斯阿Clockwordk橙色塞缪尔BVutler的方式对所有肉屈臣氏拥有Byatt 安吉拉卡特通信pany狼阿加莎克里斯蒂Mdurder东方快车常青藤普顿，伯内特和阿Fdamily财富丹尼尔笛福鲁滨逊漂流记狄更斯大卫科波菲尔爵士角Ddyle冒险的福尔摩斯玛格丽特德拉布尔瀑布达夫妮杜穆里埃丽贝卡乔治艾略特米德尔马契体育FGorster霍华德先生为此，印度之行约翰福尔斯法国中尉的女人约翰高尔斯华绥人的财产威廉戈尔丁蝇王格雷厄姆格林人的因素赫胥黎在许多夏天亨利詹姆斯黛西米勒詹姆斯乔伊斯的肖像艺术家的青年吉卜林金约翰乐Carred间谍谁排在从冷战多丽丝莱辛是基层唱歌戴维洛奇好工作美国毛姆月球和六便士，人类枷锁鸢尾Murddoch的黑王子乔治奥威尔19 84 拉什迪午夜儿童沃尔特斯科特爵士艾芬朱敬雪Thed内政穆里尔星火总理小姐布罗迪罗伯特路易斯史蒂文森金银岛 Johathan迅速格列佛游记威廉M萨克雷名利场伊夫林沃满手的灰尘奥斯卡王尔德的图片道林格雷弗吉尼亚伍尔夫达罗卫夫人，到灯塔

When Egeria writes of ceremonies held on the Octave of Easter she is not clear. While, throughout the eight days, the Lazarium was decorated and adorned like for the Octave of the Epiphany, the ceremony of the fifth day took place, not at Bethany, but at the Anastasis. Thus, there is no sure proof that a special assembly took place at Bethany during the Octave of Easter.

当时，Egeria并不清楚她所描写的是复活节八日庆的礼仪，因为，整整八天，拉匝禄被装饰的像是为了主显节八日庆，庆祝活动在第五天举行，但地点不是在伯达尼，而是复活之地，因此，没有证据证明复活节八日庆期间有特别的庆祝活动是在伯达尼举行。

That is, the shift will be bound to cause clashes between major powers. Thucydides, in his book The Peloponnesian War , observed that the war was inevitable because of "the growth of the power of Athens and the alarm which this inspired in Lacedaemon".

然而，自从伟大的古希腊历史学家修昔底德在《伯罗奔尼撒战争史》一书中提出，使得伯罗奔尼撒战争不可避免的原因是因为"雅典权力的增强以及由此而引起的斯巴达的恐惧"以来，权力转移必然是引起大国冲突已经成为了西方人的思维定式，这一点却是值得我们高度重视和认真对待的。

Manufacturing operations are located in Albuquerque, New Mexico; Elkhart, Indiana; Burbank, California; Moorpark, California, Santa Clara, California; Londonderry, New Hampshire; Ontario, Canada; Matamoros, Mexico; Glasgow, Scotland, United Kingdom; Singapore, Republic of Singapore; Bangkok, Thailand; Kaohsiung, Taiwan, Republic of China; Dongguan, People's Republic of China.

制造业务都设在新墨西哥州阿尔伯克基；埃尔德哈特，印第安纳；伯班克，加利福尼亚州Moorpark ，加利福尼亚州，加利福尼亚州的圣克拉拉，；伦敦德里，新罕布什尔州，加拿大安大略省；马塔莫罗斯，墨西哥；格拉斯哥，苏格兰，英国，新加坡，共和国新加坡泰国曼谷，高雄，台湾，中华民国；东莞，中华人民共和国。

Which was the son of Joanna, which was the son of Rhesa, which was the son of Zorobabel, which was the son of Salathiel, which was the son of Neri

3：27 约亚拿是利撒的儿子，利撒是所罗巴伯的儿子，所罗巴伯是撒拉铁的儿子，撒拉铁是尼利的儿子，尼利是麦基的儿子

Which was the son of Joaa, which was the son of Rhesa, which was the son of Zorobabel, which was the son of Salathiel, which was the son of Neri

3：27 约亚拿是利撒的儿子，利撒是所罗巴伯的儿子，所罗巴伯是撒拉铁的儿子，撒拉铁是尼利的儿子，尼利是麦基的儿子

Know that, having regard to God and for the salvation of our soul, and those of all our ancestors and heirs, and unto the honour of God and the advancement of the holy Church, and for the reform of our realm, by advice of our venerable fathers, Stephen archbishop of Canterbury, primate of all England and cardinal of the holy Roman church, Henry archbishop of Dublin, William of London, Peter of Winchester, Jocelyn of Bath and Glastonbury, Hugh of Lincoln, Walter of Worcester, William of Coventry, Benedict of Rochester, bishops; of master Pandulf, subdeacon and member of the household of our lord the Pope, of brother Aymeric (master of the Knights of the Temple in England), and of the illustrious men William Marshall earl of Pembroke, William earl of Salisbury, William earl of Warenne, William earl of Arundel, Alan of Galloway, Waren Fitz Gerald, Peter Fits Herbert, Hubert de Burgh, Hugh de Neville, Matthew Fitz Herbert, Thomas Basset, Alan Basset, Philip d'Aubigny, Robert of Roppesley, John Marshall, John Fitz Hugh, and of other faithful subjects.

知道这一点，考虑到上帝拯救我们的灵魂，和所有我们的祖先和继承人，和你们的荣誉上帝和提高罗马教会，并为我们的改革领域，我们的意见尊敬的父亲，斯蒂芬坎特伯雷大主教，灵长类动物的所有英格兰和红衣主教的罗马教会，亨利都柏林大主教威廉的伦敦，彼得温切斯特，乔斯林巴斯和格拉斯顿伯里，休林肯，沃尔特伍斯特，威廉考文垂笃罗彻斯特主教；主Pandulf ， subdeacon和家庭成员我们的主教宗的弟弟艾默里克（船长圣堂骑士团在英格兰），和杰出的男子威廉彭布罗克伯爵马绍尔群岛，威廉索尔兹伯里伯爵，威廉伯爵Warenne ，威廉伯爵阿伦德尔艾伦加洛威，瓦伦菲茨杰拉尔德，彼得适用赫伯特，贝尔德1646 ，内维尔休日，马修费赫伯特，托马斯巴萨特艾伦巴萨特，菲利浦德欧比尼，罗伯特的Roppesley ，约翰马歇尔，约翰费休，以及其他忠实科目。

Miss Huneysuckel and old Lionus could hear the singing before they saw the church buildin and that singing roused up that sweet little Widder cause at first she thought she were in heaven hearin them beautiful vioces all joined together in song, but then she couldn't believe her ears, one little angel's voice, her own little blind Betty Lou started singing one of her Bub's songs,can you believe it, one of her Bub's songs, can you believe it, one of her dead and gone husband's songs with the whole town choiring behind that sweet little girl, it was surely sweet heavenly music to her frozeup old ears.

尽管还看不到教堂，哈尼沙克和莱尼斯远远就能清楚地听到从那里传出来的歌声，那悠扬的歌声让这个寡妇兴奋起来，她还以为在天堂呢，因为只有天堂才能听到这么美妙的声音。可是，她真不敢相信自己的耳朵，一个小天使的声音飘了过来，那是她自己那个瞎眼小贝谛罗在唱巴伯的歌，你相信吗，他在唱巴伯的歌，你相信吗，所有唱诗班的人都跟着这个小女孩在唱巴伯的歌！对于哈尼沙克那快要冻僵的耳朵来说，这真是在天堂才有的美妙音乐。

Vermes, The Dead Sea Scrolls in English; A. Dupont-Sommer, The Jewish Sect of Qumran and the Essenes; M. Burrows, the Dead Sea Scrolls; FF Bruce, Second Thoughts on the Dead Sea Scrolls; WS LaSor, The Dead Sea Scrolls and the NT; R. deVaux, Archaeology and the Dead Sea Scrolls; JH Charlesworth,"The Origin and Subsequent History of the Authors of the Dead Sea Scrolls: Four Transitional Phases among the Qumran Essenes," RQum 10:213-33; CD Ginsburg, The Essenes.

杜邦，索默，犹太人教的昆兰和爱色尼；先生伯罗斯，死海古卷；法郎布鲁斯，第二思考死海古卷；是LaSor ，该死海古卷和NT ；河deVaux ，考古学与死海古卷；家查尔斯沃思说：&起源和更强的历史作者的死海古卷：四过渡阶段之间的昆兰爱色尼&， RQum 10：213 - 33 ；裁谈会金斯伯格，在爱色尼。

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时，滚道或滚动元件褪色是很常见的特征。