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Infectious bursal disease has still been one of the most important diseases in poultry industry around the world and vaccination is now the most effective measure for the disease control.

传染性法氏囊病仍然是世界养禽业影响最大的传染病之一。疫苗接种是目前控制IBD最有效的措施。

Objectives: To investigate the diversity of expression of structural protein among different infectious cloacal bursal disease viruses.

目的 :了解不同传染性腔上囊病病毒株结构蛋白表达的差异。

At present, Infectious Bursal Disease is widespread epidemic and results in serious damage to the poultry of China, although several kinds of vaccines are applied.

目前使用的多种疫苗仍未能有效控制鸡传染性法氏囊病的发生,原因是疫苗质量难以保证和免疫程序或方法不当。

Consequently, it seems to be particularly important to master the methods of atypical bursal disease diagnosis.

近年来,传染性法氏囊病发病逐渐趋于缓和,呈现出非典型化,给临床诊断带来困难,因此,掌握非典型法氏囊病的诊断方法就显得尤为重要。

Infectious Bursal disease Virus; vaccine ; production ; application

传染性法氏囊病病毒;疫苗;制造;使用

Infectious bursal disease virus ; Epitope; Analysis

传染性法氏囊病病毒;抗原表位;序列分析

Infectious bursal disease of chicken,简称IBD

传染性的;有导致疾病的可能。

infectious bursal disease is a high degree of exposure to sexually transmitted diseases, the chicken will lead to decline in immune function, the impact of other immune diseases, the aquaculture industry to bring great harm.

传染性法氏囊病是一种高度接触性传染病,会导致鸡体免疫功能下降,影响其他疾病免疫,给养殖业带来极大的危害。

Key words: chicken; infectious bursal disease virus; variant; bivalent attenuated vaccine; immunogenicity

关 键 词:鸡;传染性法氏囊病病毒;变异株;二价弱毒疫苗;免疫原性

The possibility of producing infectious bursal disease virus on Second Chicken Embryo Fibroblast cells was studied.

传染性法氏囊病是对养鸡业危害最严重的病毒性传染病之一,目前该病尚无特效治疗手段,以预防接种为主,所以需要大量价格低廉,免疫原性好的疫苗。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

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