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This experiment will investigate the protective effect of Shenfu Injection to the liver of endotoxic shock in rats, and also its possible mechanisms.

本实验将研究参附注射液对内毒素休克大鼠肝脏的保护作用及可能的作用机制。

Therefore, how to prevent and cure endotoxic shock is a big issue that needs to be concerned. LPS is the primary cause for endotoxic shock.

因此,如何防治内毒素休克的发生是重症医学所关注并亟待解决的重大课题。

These data highlight that LPS can up-re-gulate ICAM-1 protein and mRNA expression in different tissues of the mice with endotoxic shock.

上述结果表明,在LPS诱导的内毒素休克小鼠的多种脏器中ICAM-1蛋白和mRNA表达显著增加。

Endotoxic shock animals model can be created by large dose of LPS injection.

1通过静脉注入大剂量LPS的方法成功复制了内毒素休克动物模型。

Objective To study the protective effects of a melanocytestimulating hormoneand its analogueon endotoxic shock mice.

目的 研究α黑素细胞刺激素及其类似物对内毒素休克小鼠的保护作用。

The component of Gram-negative bacteria's cell wall, LPS, is the major cause of endotoxic shock.

革兰氏阴性细菌细胞壁成分内毒素即脂多糖,是引起内毒素性休克的主要因素。

However, the mechanism of development of inflammatory damage in organ failure during endotoxic shock is still not yet known, and further, it is more difficult in clinical treatment.

然而内毒素休克时,循环衰竭器官组织炎症性损伤的确切发病机制尚未阐明,且在临床治疗上仍是一个非常棘手的问题。

It has been established that maybe inflammatory factors themselves are vascular active component, which is crucially involved in the pathogenesis of endotoxic shock.

以往实验证明许多炎症介质本身即是血管活性物质,是参与休克发生发展的主要因素。

It is our first to find that H2S may up-regulate HO-1/CO in the tissue of endotoxic shock rat model.

4首次发现H2S可上调内毒素休克大鼠组织中的HO-1/CO通路。

Objective To study the effects of calcium sensit izer MCI-154 on myocardial sensitivity to calcium during endotoxic shock in rat s.

目的 研究钙增敏剂对内毒素休克大鼠心肌钙敏感性的影响。

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