休克

Both dopamine and norepinephrine are recommended as first-line vasopressor agents in the treatment of shock.

在休克的治疗中，多巴胺和去甲肾上腺素都被推荐为一线血管活性药物。

In this multicenter, randomized trial, we assigned patients with shock to receive either dopamine or norepinephrine asfirst-line vasopressor therapy to restore and maintain blood pressure.

在这个多中心、随机对照试验中，我们指定休克病人接受多巴胺或者去甲肾上腺素治疗作为恢复和维持血压的一线血管活性治

Shock after right ventricular MI will usually respond partially to volume expansion; however, vasopressor agents may be needed.

右室MI休克通常会对容量扩张起反应，但可能需要血管加压药。

This decision is generally based upon signs of peritoneal penetration, unexplained shock, ileus, organ evisceration, free gas on radiographic examination or evidence of bacteria or plant debris following abdominocentesis or peritoneal lavage.

这一决定是基于一般原因不明的休克后腹腔渗透的迹象，肠梗阻，切除内脏器官，或植物的自由气体对X光检查或细菌的碎片下列证据腹腔穿刺或腹腔灌洗。

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质，三羟异黄酮的作用机制主要包括：①抑制蛋白酪氨酸激酶活性，可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递，导致癌细胞增殖受抑；②弱雌激素作用：可通过与体内雌激素受体结合，并可增加细胞内性激素结合球蛋白的合成，增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性；③拓扑酶Ⅰ和Ⅱ抑制剂，抑制细胞活性；④上调细胞周期性负性调节因子P21WAF1/CIP1的表达，使之负性调节因子作用增强；⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长；⑥其他：抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

In heat shock protein gp96-peptide complexes induced tumor rejection model,antigen specific CD8T cells adoptively transffered into perforin knock out mice failed to proliferate and differentiate into CTLs whereas co-transfer of wide type NK cells rescued the clonal expansion and CTL differentiation of transferred CDST cells.These results suggested important immuno-modulatory roles of perforin and presumably different roles of perforin secreted by NK cells versus by CD8~+ CTLs.

例如，在热休克蛋白Gp96-肽复合体所诱导的抗肿瘤免疫应答中，穿孔素基因敲除小鼠中单独回输的野生型CD8T细胞不能产生有效的抗肿瘤免疫应答，而同时回输野生型NK细胞能够恢复CTL应答。

The loading process of trehalose has no effect on apoptosis of platelets. The efficacy of trehalose plus phosphate in suppressing apoptosis of platelets during cryopreservation is superior to that of only trehalose. Compared to 6% DMSO and 2% DMSO plus TS, trehalose plus phosphate can retain the same platelet count, superior hypotonic shock response and platelet aggregatory reaction to ADP, and lower apoptosis rate of platelets. Platelets cryopreserved with trehalose plus phosphate can retain intact ultrastructure.

结论血小板负载海藻糖的过程不会促进血小板的凋亡；海藻糖保存血小板时，联合应用磷酸盐在抑制血小板凋亡方面的效果优于单独应用海藻糖；海藻糖联合磷酸盐冻存血小板的长期效果较稳定，其维持血小板回收率的效果与6%DMSO及2% DMSO联合TS相同，维持血小板低渗休克反应、聚集功能及抑制血小板凋亡的效果优于6%DMSO及2%DMSO联合TS，并能较好地维持血小板的超微结构。

That's what caused your anaphylactic shock.

这是导致你过敏性休克的原因

This is called anaphylactic shock.

这就是所谓的过敏性休克。

I have a condition I'll go into|anaphylactic shock, when I...

我会过敏性休克如果我。。。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。