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Objective To study the effects of heat-shock protein fusion protein on the differentiation and maturation of human monocyte derived dendritic cells.

目的:研究热休克蛋白融合蛋白对人树突状细胞分化成熟的刺激作用。

Objective: To determine the expression of heat shock protein 70(HSP70) in gastric mucosa.

目的:探讨热休克蛋白70(heat shock proteins 70, HSP70)在人胃黏膜组织中的表达。

Role of heat shock proteins in gastric mucosal protection.

休克蛋白在胃黏膜保护中的作用。

Since the findings of Murry and Currie et al . that ischemic preconditioning and heat shock response could protect evidently myocardium against ischemia-reperfusion injury in the middle of 1980s, endogenous myocardial protection has drawn widespread attentions.

摘 要:自上世纪80年代中期Murry及Currie等分别发现缺血预适应(ischemic preconditioning, IPC)与热休克反应(heat shock response, HSR)具有明显的心肌保护作用以来,有关心肌内源性保护作用的研究引起了学术界的广泛关注。

Methods The recombinant sequence for two CEA epitopes was tandemly engaged and inserted into-upstream of in-frame-varied HSP70 of Mycobacterium tuberculosis to construct a gene vaccine.Balb/c mice were muscularly injected with recombinant DNA vaccine;negative control (mice were injected with normal saline), positive control (mice were injected with DNA vaccine harboring tandem CEA epitopes plus aluminium hydroxide adjuvant) and experimental group(mice were injected with PCITri CEA625-667-met HSP70) were set up.

在已经构建含有变异热休克蛋白序列的基础上,插入重组CEA串联表位的编码片段获得CEA串联表位-HSP融合基因疫苗。3次肌肉注射免疫Balb/c小鼠,设立注射生理盐水的阴性对照组、注射氢氧化铝佐剂混悬CEA串联表位的阳性对照组及注射pCITriCEA625-667-mtHSP70的实验组。

The treatment group consisted of 44 patients who received mutine thempv(①rapid and adequate fluid resuscitation,④)rapid restoration of important organ circulation bv treatment with cardiovascular drugs,⑧early enteral nutritional support to protect gastrointestinal mucosal barrier.et al·+CVVH.The control group consisted of 32 patients who received only routine therapv.

回顾性分析76例严重脓毒症伴脓毒性休克患者,分为两组,常规综合治疗组32例,采用快速而充分的液体复苏、血管活性药物改善脏器灌注、早期肠道营养保护肠黏膜屏障等综合治疗;综合治疗+CVVH组44例,在常规综合治疗基础上加CVVH治疗。

76 patients were divided into either the treatment group or the control group.The treatment group consisted of 44 patients who received mutine thempv(①rapid and adequate fluid resuscitation,④)rapid restoration of important organ circulation bv treatment with cardiovascular drugs,⑧early enteral nutritional support to protect gastrointestinal mucosal barrier.et al·+CVVH.The control group consisted of 32 patients who received only routine therapv.

回顾性分析76例严重脓毒症伴脓毒性休克患者,分为两组,常规综合治疗组32例,采用快速而充分的液体复苏、血管活性药物改善脏器灌注、早期肠道营养保护肠黏膜屏障等综合治疗;综合治疗+CVVH组44例,在常规综合治疗基础上加CVVH治疗。

Objective To raise the level of regarding congnition,prevention,diagnosis and therapy on multiple organ dysfunction syndrome.Methods Report the process and correlative therapy on one case who occured with MODS involving 6 organs after hemorrhagic shock lead to heartbeat and respiration stopping suddenly and resuscitated resulting in left nephrostome titanium nip falled off accidentally from left kidney lymphatic fastening.

目的 提高对器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)的认识、预防、诊断、治疗水平方法报告成功抢救1例经腹腔镜左肾淋巴管结扎手术后左肾静脉钛夹意外脱落失血性休克,导致心跳呼吸骤停复苏后再手术并发MODS累及6 脏器功能衰竭过程及有关治疗,并复习相关文献,介绍目关于MODS的研究进展。

Incidence of nonfatal and fatal stroke and new-onset diabetes were also lower in the losartan group.

且losartan组非致命性或致命性休克和新发生糖尿病的机率也更低。

Result: The incidence of obstetric hemorrhagic shock in the study was 0.65%.

目的:探讨产科失血性休克发生的原因和防治方法。

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这两个团体间的分歧难以掩饰。

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