代谢物

Epidemiological studies, clinical trials or both have examined the effects of fiber on carbohydrate metabolism, lipid metabolism, colon cancer, diverticular disease, constipation, weight reduction, and other conditions.

富含〓的底物在人体内将被氧化代谢为〓〓和水。通过气体同位素质谱仪测定一定时间内呼气中的〓〓比值变化，可以评价摄入的营养物质在体内吸收、代谢的情况。

The molecule mechanism of anti-atherosclerosis is related with the channel of regulating PPARγ. As a new and higher specificity PPARγ excitomotory, Maixinkang is anticipated to supply more effective treatments for anti-atherosclerosis and lipid anomal-metabolism.

其抗动脉粥样硬化作用的分子机制与过氧化体增殖物激活型受体γ调控途径有关，有望成为中医药领域中新的、特异性较高的过氧化体增殖物激活型受体γ激动剂，为抗动脉粥样硬化和脂代谢异常提供更佳的药物选择。

And the IC50 values of all tested compounds did not change at various times. The panel of CYP3A4 polymorphic enzymes will be tested against various drugs, kinds of fluorogenic substrates and CYP3A4-specific substrate to identify potentially adverse drug-CYP in order to generate predictive information applicable in personalized medicine.

多种荧光底物、探针底物和大量的上市药物对人细胞色素P450 3A4野生株及其突变株的体外代谢研究正在进一步进行中，旨在建立一种高通量、简便、快捷的针对于CYP3A4遗传多态性的药物筛选平台，从而为临床个体化用药提供科学依据。

With the development of experimental technology and people's further knowledge to explore the biological activity of resveratrol, resveratrol derivatives and their analogues were found in grape and many other plants, which were thought to be the metabolizable products of resveratrol.

随着白藜芦醇生物活性的深入认识和实验技术的不断更新，人们在葡萄等多种植物中发现了白藜芦醇衍生物及其类似物，这些衍生物和类似物被认为是白藜芦醇的代谢产物。

With the development of experimental technology and people's further knowledge to explore the biological activity of resveratrol, resveratrol derivatives and their analogues were found in grape and many other plants, which were thought to be the metabolizable products of resveratrol.

随著白藜芦醇生物活性的深入认识和实验技术的不断更新，人们在葡萄等多种植物中发现了白藜芦醇衍生物及其类似物，这些衍生物和类似物被认为是白藜芦醇的代谢产物。

Till now, Studies on Sorangium have mainly been carried out on its intriguing, novel and diverse bioactive metabolites and the genes for synthesis of these metabolites. However, to our knowledge no studies on the cellulolytic activity, the unique and basic property of Sorangium among myxobacteria have been reported yet.

目前国内外关于堆囊菌的研究大都仅仅局限于新颖、功能不同的活性代谢产物的筛选和鉴定以及代谢产物合成功能基因寻找和改造方面，而对于堆囊菌能降解纤维素大分子底物这一有别于其他粘细菌的自身独特的、最基本的特性，目前尚未见到相关的研究报道。

All dates were analyzed by the principal component analysis through using the SIMCA-P 10.0 software. Result: The PCA demonstrated that the metabolome between treated group and control group had difference in rat urine sample after of 22 days administrated, for treated group 169 kinds of biomarkers were found including oxalacetic acid, malic acid, 2-ketoglutaric acid, NE, arachidonic acid, 5-HIAA and other compounds, the result was consistent with pharmacological effects of R.coptidis , such as antiinflammatory, inhibiting biosynthesis of CA biosynthesis, anti-central nerve and energy metabolism inhibition.

结果：给药22 d，黄连组与对照组大鼠尿样代谢组有较大差异，发现了169个生物标记物，其中可能的化合物为草酰乙酸、苹果酸、2-酮戊二酸、去甲肾上腺素、花生四烯酸、5-羟吲哚乙酸等物质，这与黄连抗炎、阻止儿茶酚胺的生物合成、抑制中枢神经、降低能量代谢的药理作用相一致。

Most of the studies have demonstr ated that glutamine serves metabolic roles for macrophage.By glutamiolysis pat hway,glutamine provides ATP for the cellular metabolism,intermediates for the biosyn thesis of parine,pyrimidine and nuclecotides,and nitrogen for the formation of glucosamine,GTP and NAD+.

研究表明谷氨酰胺是单核巨噬细胞主要的代谢底物，通过谷氨酰胺酵解途径，为细胞代谢提供能量；为细胞合成DNA和mRNA提供嘌呤、嘧啶、核苷酸生物合成前体；提供氨基葡萄糖，GTP和NAD+合成的氮前体。

According to the structure of BOPs, cometabolic substrate that can induce the microbial cometabolism is added to the bio-reactor to improve the biodegradation efficiency.

针对目标污染物的结构性质，以合适的共代谢基质作为诱导物，采取共代谢的方式也可以提高难降解有机物的生物降解速率。

For long-term treatments, the rat administered daily by gavages for six weeks, the results of OGTT showed that guava fruit water or alcohol extracts could reduce the plasma glucose level in the diabetic Wistar rats, however there was on significant difference in insulin level among all tested groups. The results of carbohydrate metabolism showed diabetic Wistar rats administered with 200 or 400 mg/kg BW of guava fruit water or alcohol extracts could decrease more than 15% glucose-6-phosphatase and fructose-1,6-bisphosphatase activities, and it also increase more than 12% glucose-6-phosphate dehydrogenase activities to reduce inhibitory hexokinase from reducing glucose-6-phosphate level.

在醣类代谢方面，实验结果发现糖尿病鼠灌食番石榴果实水及乙醇萃取物六周后，肝脏醣质新生作用中丙酮酸合成肝醣之关键酵素glucose-6-phosphatase及fructose-1，6-bisphosphatase的酵素活性会降低15%以上；另一方面肝脏glucose-6-phosphate dehydrogenase酵素活性则明显增加12%以上，并造成glucose-6-phosphate浓度减少，进而降低其对hexokinase的抑制(因为hexokinase受其代谢产物G-6-P的浓抑制)，因此加速肝脏葡萄糖的糖解作用。

I can still vividly recall the impressive scenes you gave. You were among my friends and relatives who accompanied me from my house to the seaport and when the porters were slow to show up, you obligingly carried my suitcase for me.

你对我的种种感人情意，使我记忆犹新，那天你随着我的亲友从家里送我上轮船，搬运工迟迟不来，你毅然替我提着皮箱上船。

St. Nicholas became the patron saint of Russia, where he was famous for his red cape, flowing white beard, and bishop's mitre.

圣尼古拉成了俄罗斯人的守护神，在那里，他以身披红斗篷，留着飘逸的白胡须，戴着主教法冠而闻名。