代谢物

The peroxisome proliferator-activated receptors play an important role in adipocyte differentiation and fatty acid metabolism, activation of PPAR may induce the differentiation of adipocyte,influence the expression of genes involved in lipogenesis and fatty acid oxidation,eventually lessen ectopic fat accumulation and improve the impaired insulin signaling,so the medicine which targets to the control point of FFA metabolism would be hopeful in the treatment of a cluster of metabolic abnormalities resulted from insulin resistance.

过氧化物酶体增殖物激活受体在脂肪细胞分化、脂肪酸代谢中起重要作用，PPAR及其所调控基因的激活可促进脂肪细胞分化、减少脂质产生、增加脂肪酸氧化，从而减少脂质的异位沉积，进一步改善损伤的胰岛素信号转导通路，逆转胰岛素抵抗。针对脂肪酸合成及氧化的关键调控点的药物可能是今后治疗胰岛素抵抗引发的一系列代谢异常的新的靶点。关键词过氧化物酶体增殖物激活受体；脂肪酸代谢；胰岛素抵抗

However, there is no difference for NAT2 rapid and slow acetylator between two groups.

吃红烧鱼因素在NAT2的快速酶中，特别是在野生纯合型中直肠腺瘤复发的相对危险度有增高趋势，提示了NAT2〓4等位基因编码快酶型NAT，可能在红烧鱼产生的杂环胺类化合物中代谢中加速其N-乙酰基化代谢过程，从而加速其代谢为终致癌物而与肠粘膜上皮细胞的DNA产生加成物，损伤其遗传物质。

Nevertheless, Smoking could interact with wild type of NAT2 and increase the relative risk of rectal adenoma recurrence significantly. It is suggested that NAT2 might involve the metabolism of pre-carcinogen generating from tobacco and alter the susceptibility of cancer. Meanwhile, the NAT2〓4 alleles encode rapid acetylator of NAT2 would increase the risk of adenoma recurrence among those high-risk people with habit of fried fish intake.

吃红烧鱼因素在NAT2的快速酶中，特别是在野生纯合型中直肠腺瘤复发的相对危险度有增高趋势，提示了NAT2〓4等位基因编码快酶型NAT，可能在红烧鱼产生的杂环胺类化合物中代谢中加速其N-乙酰基化代谢过程，从而加速其代谢为终致癌物而与肠粘膜上皮细胞的DNA产生加成物，损伤其遗传物质。

The power-time curves of E.coli reacting with Co-SG at different temperature has been determined by microcalorimtric method The multiplication rate constant k, generation time G,bacterial growth inhibition ratio I,total thermogenetic quantity Q, the heat quantity of a single bacterium Q_(0) and the heat quantity of a single bacterium per minute have also been calculated according to the power-time curves.

用微量热法测定了大肠杆菌及其在Co -SG配合物作用下的热谱曲线，计算了速率常数k ，传代时间G、抑制I、总产热量Q、单个细菌的产热量Q0 和每分钟单个细菌的产热量 Q0 ，建立了部分代谢参数之间的关系，探讨了大肠杆菌在不同温度和Co -SG作用下的代谢抑制，发现可用t、tr、tg和 Q0 定量表征在不同温度下大肠杆菌的生长代谢和药物的抗菌活性。

The quality of purified 2-KGA from its fermentation products was up to industrial standard. In addition, several hexoses, such as D-glucose and D-sorbitol can be utilized to synthesize 2-KGA by this newly-mixed culture. The growth and anabolism of the B529-V6 were studied in 4M〓 and 300M〓 fermentor respectively. The results showed that its growth and anabolism were affected by carbon sources, ratio of D-glucose and L-sorbose, nitrogen sources, growth factors, inoculum quality and culture condition including the initial pH value, temperature and ventilation.

新菌系B529-V6表现出了较强的高浓度L-山梨糖耐受能力、较高的底物代谢速率和较高的2-KGA转化能力，在8％山梨糖浓度的发酵培养基中培养48h，糖酸转化率较对照菌系提高了5.94％；山梨糖浓度提高至10％，其生长代谢受影响程度较小，且能不同程度地利用葡萄糖和山梨醇为底物，合成维生素C前体-2-酮基-L-古龙酸（2-KGA），其发酵产物2-KGA经反相高效液相色谱分析其质量符合工业化生产要求。

Biodegradation is a dynamic process, where the diffusion of hydrocarbon to oil water contact, the diffusion of metabolites away from the reaction site to the oil column. Late charging and mixing occurred in the reservoir also control on the degree of biodegradation.

生物降解是一个动态过程，烃类不断向油水界面扩散，降解过程中新形成的代谢物从油水界面向油柱扩散，后期充注及油藏内的混合作用也是控制生物降解作用程度的重要因素。

However, ST and its aglycone were detected in all tissues, urine and feces. With the aid of LC/MS/MS system to analyze urine sample obtained from a ST tube-fed rat, we confirmed that ST and sesaminol existed in urine.

而在血浆以及各组织脏器中，皆测得ST及其代谢物sesaminol的存在；进一步将大鼠尿液检体以LC/MS/MS进行分析，结果证实尿液中确实含有ST及sesaminol分子。

After twice dichloromethane liquid-liquid extraction, the extracts were cleaned with PRS column.

建立了液相色谱-串联质谱测定水产品中孔雀石绿及其代谢物残留的检测方法。

At 90% sensitivity, these metabolites had specificities of 74%, 51%, and 34%, respectively.

在敏感度为90%的情况下，这三种代谢物的特异性分别是74%、51%和34%。

Durazzo says the next step for the researchers is a comparison of physical changes in the brain ---- olume, metabolites (the chemical products of brain metabolism), and blood flow ---- in the same group of subjects during extended abstinence from alcohol.

Durazzo说研究者的下一个任务就是对继续戒酒的这同一组受试者比较他们的大脑的生理改变，如大脑的容量、代谢物（大脑新陈代谢产生的化合物）和血流。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷