代谢

SOFE can provide fuel calories for hypso-energy consumption after burn,modulate the metabolism,depress postburn hypermetabolism,retrieve the negative nitrogen balance,and reduce the body weight loss.

SOFE提供了烧伤后高热量消耗所需要的热能，替代蛋白质的分解，它还可以调节机体代谢状态，逆转烧伤后高代谢，降低高代谢造成的负氮平衡，缓解体重下降。

Part 1: Fifty-four healthy cross-bred(Luxi×Limousin) beef cattle were selected to study the energy and protein metabolism rules and requirement at the age of 4~6 month. The results showed that the digestibility of DM , OM and energy were 59.68±5.46%, 64.10±7.82% and 66.60% respectively;the metabolizability of gross energy and digestible energy were 56.95% and 85.51%.

第一部分选用54头健康、体重相近的3月龄利木赞×鲁西黄牛杂交牛研究了4～6月龄阶段的能量和蛋白质需要量及其代谢规律，结果表明：犊牛对日粮的DM消化率为59.68±5.46%，OM消化率为64.10±7.82%；能量的平均消化率为66.60%，总能代谢率和消化能代谢率分别为56.95%和85.51%。

The result indicated that ZXTMN group excelled the western medicine in the aspects of ameliorating symptom and hemodynamics, adjusting sugar and lipid metabolism, and reducing urine albumin and pltaelet adhesiveness and aggreagtion. The mechanism, which ZXTMN prescription could protect renal function, probably was (1) decreasing the level of sugar and glycosylated ferrohemoglobin;(2) decreasing AR activity of erythrocyte, improving SDH activity of erythrocyte, reducing accumulation of sorbitol in the erythrocyte, thus ameliorating the polyol metabolism;(3) accommodating lipid metabolism;(4) ameliorating coagulation, gathering, thick and mucosity of patient blood.

结果表明，止消通脉宁治疗组明显优于西药对照组，在改善症状，调整糖、脂代谢，减少尿白蛋白，改善血流变，降低血小板粘附和聚集等方面具有显著的疗效，分析其治疗早期DN的机制可能有以下几个方面：（1）降低血糖和糖化血红蛋白；（2）降低DN患者红细胞AR活性、提高SDH活性、减少红细胞内山梨醇积聚从而改善多元醇代谢；（3）调节脂质代谢；（4）改善DN患者血液凝、聚、浓、粘状态，抑制血小板的粘附聚集，从而改善肾脏微循环，保护肾功能。

The bio-degradation pathways of NP would be that the long branches in nonyl of NP are firstly degraded into short methyl branches, which come into being a series of short chain alkyl phenols with different branch structures. The middle products should be further metabolized into simpler compounds, such as benzene acetic.

污水生物处理过程中壬基酚可能的初级生物代谢途径是壬基上的长支链断裂为短的甲基链，生成一系列带有不同分支结构的短链烷基酚类代谢产物，进一步的代谢产物有苯乙酸。

This because NPY acted on sympathetic nerve obstructively and insulin was absolutely or relatively inadequate, which affected glycometabolism, lipometabolism and proteometabolism seriouly, and a lot of water was egested from urine on account of hyperglycosuria and osmosis-diuresis.

这可能进一步说明由于长期有氧运动，糖尿病大鼠增强了胰岛素分泌水平及组织对胰岛素的敏感性，促进了组织对糖的吸收和利用，改善了糖代谢紊乱及能量代谢异常，使糖尿病大鼠为满足机体能量代谢需要，而出现脂肪、蛋白质分解加剧得到缓解。

We employed HPLC to measure the metabolites of caffeine in the whole blood and calculated the ratio be between the metabolite and caffeine, which was used as index to evaluate the effect of Qingkailing injection on rat CYP1A2 activity in vivo ; We also detected the CYP1A2 and CYP2D6 activity in microsomal reconstituted system by analysis of phenacetin metabolism and dextromethorphan metabolism with HPLC.

通过HPLC法测定全血中咖啡因的代谢率，观测清开灵注射液对大鼠CYP1A2活性的影响；通过HPLC法测定大鼠肝微粒体重组系统非那西丁的代谢比率，确定清开灵注射液对大鼠肝微粒体CYP1A2亚型的作用；测定大鼠肝微粒体重组系统右美沙芬的代谢比率，确定清开灵注射液对大鼠肝微粒体CYP2D6亚型的作用。

Next, BALB/c mice were orally infected with Y. pseudotuberculosis and its ompR mutant to study metabonomic variation of different intestine-associated organs after 24 h infection. The results showed that a majority of metabolites were decreased during this acid adaptation process, but phosphoenolpyruvate, 5'-GMP, 5'-AMP, 5'-UMP, GDP/GTP of wild type strain and lactate, Tyr, phosphoenolpyruvate, 5'-AMP、GDP/GTP of the ompR mutant strain were increased.

为了探讨病原细菌感染动物后特别是在酸性环境下代谢物的变化规律，首先在体外模拟假结核耶尔森氏菌及其全局性调控因子OmpR突变株在适应酸性环境时所引起的菌体自身的代谢变化，然后通过BALB/c小鼠口服感染耶尔森氏菌，研究小鼠感染病原细菌24h后各种相关器官的代谢变化。

The daily total metabolic rates were determined for 31 fish with closed respirometers. In addition, resting daily total metabolic rates were determined for 20fish by confining the fish into a cage within the respirometer. The fish weighed 72.9-133.3g and were fed different ration levels from starvation to 4% bw / day at 25℃.

在25℃不同日粮水平（饥饿─4％体重／d）条件下，采用封闭式呼吸仪测定了31尾鲇鱼（体重72.9─133.3g）的日总代谢率，然后，将鱼限制在呼吸室中的限动笼内测定了其中20尾鲇鱼的静止日总代谢率，并计算出了鲇鱼的特殊动力作用和活动代谢率。

Subsequently, the optimized technology was successfully scaled up to 〓 pilot bioreactor scale by using the parameter simulation method. The scale-down strategy was applied to the 100〓 fermentation tank to ascertain that the determining factor which affects metabolic flux distribution reasonably had changed to the dissolved oxygen control. After resolution of the DO limitation, the optimized technology inhibited the shift on 100〓 production scale correspondingly, notable commercial returns was gained as a result.

随后基于过程参数拟合的方法成功地将抑制代谢流迁移的新工艺放大到12〓规模，并通过规模缩小证实了100 〓生产规模的发酵过程中限制代谢流合理分配的限制性因素已经发生了变化，此时DO的控制成为优化的前提，通过改善供氧条件之后优化的工艺在生产规模也成功的克服了代谢流的迁移，取得了显著的经济效益。

It is well known that P450 enzymes in mammals represent products of a supergene family, but the majority of compounds are metabolized by three different P450 families.

现在认为大多数药物是由P450 Ⅰ、Ⅱ、Ⅲ三个家族代谢的。clau对映体的羟化代谢反应是由哪一个家族的亚酶代谢的呢？

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失