代谢

The metabolic passways of nimetazepam and nitrazepam in rat were studied by comparing the metabolites of them.

采用GC-MS比较了硝基安定和尼美西泮在大鼠体内产生的代谢产物，确定了尼美西泮在大鼠体内的代谢途径。

Objective:To investigate glucose metabolism and effect of glucocorticoid in idiopathic nephrotic syndrome.

目的：研究原发性肾病综合征患者糖代谢及应用糖皮质激素治疗对糖代谢的影响。

The functional allele at the W locus is Ipmyb2, which was newly found in Chinese populations, and it differs mainly in the intron regions from those of the reported allele Ipmyb1; in comparison to Ipmyb2, the newly found second allele ipmyb2 has eight substitutions in the exons, a 6-bp deletion, and a 19-bp deletion, causing ORF shifting, and exists mostly in white-flowered individuals.

以上结果表明：1花青素代谢途径上酶基因的位点均有一定程度的多态，其中尤以ANS为最高；调控基因ipmyb2的核苷酸缺失造成该基因停止功能，使其纯合子的个体开白色花。2授粉者所介导的花色表型选择确实在中国种群中发生，有可能进一步增加花色代谢途径上基因位点的遗传变异。

Early researches have been limited to animal experiment of detecting metabolism of brain. With the development of magnetic resonance spectrum, studying in vivo has come ture on the biochemistry metabolism's level, which makes a new breakthrough for us to continue research of IGE afterward.

以往的研究仅限于动物实验的方法检测其脑内的代谢变化，现在随着磁共振波谱(Magnetic Resonance Spectroscopy， MRS)的应用，无创地从生化代谢水平上研究活体已成为现实，为这一类疾病的研究打开了新的局面。

The prediction equations of nutritional requirements about digestible energy, metabolizable energy, digestible crude protein, and protein deposited for stall-feeding growing crossbred Boer goats were:DE, kJ/d=588.31W0.75 9.25W 879.9 r=0.5712, p=0.013ME, kJ/d=482.42W0.75 7.57AW 721.57 r=0.5713, p=0.013DCP, g/d=(0.03AW 1.27) W0.75 r=0.9869, p=0.0131 PD, g/d=(0.03W 0.03) W0.75 r=0.9993, p=0.0007 When the average daily gain stage is from 0 to 200g/d,for the stall-feeding growing crossbred Boer goats, aged at 3~6 months, Metabolic rate of gross energy of the diets is 0.55; digestibi I ity of crude protein is 0.56; The protein requirement of per live weight gain for meat goats is 0.31 g PD/g gain .

舍饲波杂肉羊生长期消化能、代谢能、可消化粗蛋白质、沉积蛋白质需要量的估测模型分别为： DE，kJ／d=588.31W~(0.75) 9.25△W 879.9 r=0.5712，p=0.013 ME，kJ／d=482.42W~(0.75) 7.57△W 721.57 r=0.5713，p=0.013 DCP，g／d=(0.03△W 1.27)W~(0.75) r=0.9869，p=0.0131 PD，g／d=(0.03△W 0.03)W~(0.75) r=0.9993，p=0.0007 3～6月龄舍饲生长期波杂肉羊增重范围为0～200g／d时，日粮总能代谢率平均为0.55，粗蛋白质的消化率平均为0.56；每增重1g体沉积蛋白质需要量为0.31g。

English Outline A one-term introductory biochemistry course that covers the biochemistry of the living state; the chemistry of amino acids, proteins, nucleic acids, carbohydrates, lipids, and steroids; energy transformations and chemical reactions in living cells; action of hormones; and self-regulation and self-replication of living organisms.

Chinese Outline 本课程属於生物技术的基础课程，授课内容强调基本生化原理，介绍细胞组成份〈包括核酸、蛋白质、醣类和脂质〉的化学、生物活性及代谢，并分别阐明代谢作用与基因表现的调节机转，辅以现今生化尖端学术研究的介绍，希望能以一学期的紧密课程，让学生了解现代生化科技领域的轮廓，作为日后深造或从事生化科技行业的奠基。

By using Morris Maze task,The results indicated the learning and memory impairment was continuously maintained by MA-induced neurotoxity,PF_(11) significantly antagonized the learning and memory impairment by MA-induced neurotoxicity, Motor incoordination was studied by using the rotating rod method in mice,PF_(11) markedly alleviated the injury induced by MA.using HPLC-ECD,there were markedly decrease the contents of DA,DOPAC,HVA and 5-HIAA,PF_(11) markedly antagonised decrease of DA in MA-induced neurotoxicity.

在Morris水迷宫空间辨别性学习记忆实验中，甲基苯丙胺中毒小鼠找到平台的潜伏期明显延长，PF_(11)沈阳药科大学硕士学位论文中文摘要能显著缩短延长的潜伏期。转棒实验表明，甲基苯丙胺中毒小鼠运动协调性显著降低，而PF；；能桔抗小鼠运动协调性的降低。甲基苯丙胺中毒小鼠大脑内多巴胺及其代谢产物DOPAC、HVA含量明显降低，另外，5一羟色胺的代谢产物5－HIAA明显降低，而PF；；与甲基苯丙胺联合给药小鼠大脑内DA、HVA的含量显著升高。这些结果提示PF；通过影响多巴胺神经系统而桔抗甲基苯丙胺神经毒性的作用。

To elucidate the relationship between DNA damage and smokers' transferase genetic polymorphism.

［目的］探讨吸烟者Ⅰ相代谢酶CYP1A1和Ⅱ相代谢酶GSTM1基因多态性与DNA损伤的关系。

Sodium propionate and sodium pyruvate could promote liver gluconeogenesis by up-regulating the abundance of PEPCK-C mRNA in the hepatocytes, but the up-regulation was limited.

表明，丙酸钠、丙酮酸钠能通过上调体外培养的新生犊牛肝细胞PEPCK-C mRNA的表达而促进肝糖异生代谢，但上调作用是有限的；胰岛素能通过下调体外培养的新生犊牛肝细胞PEPCK-C mRNA的表达而抑制肝糖异生代谢，且下调作用呈剂量依赖性；胰高血糖素与胰岛素作用刚好相反；瘦蛋白未起直接的调节作用。

The axial, coronal and oblique images generated with these techniques were independently reviewed for LVA by two radiologist and one ENT doctor, and the numbers of scan designators required for diagnosis of LVA were compared.

前庭水管(vestibular aqueduct，VA)是连接膜迷路与内淋巴囊的管道，正常大小的VA 是维持内淋巴液代谢所必须的，而内淋巴液的正常代谢对维持正常的听力至关重要。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。