代谢

BE a person machine body because of metabolism but creation various metabolism thing metabolism don't go out, cause'common cold', mouth cavity ulcerate, various burning disease, various wet, oil, stem skin disease, Sao Yang, ache etc. machine quality disease, these be"don't disease";Person machine body the organ have no decrepitude, but the body falsely can't go out various metabolism thing metabolism not, can also cause the paroxysm relapse and these be also"don't disease".

是人机体因新陈代谢而产生各种代谢物代谢不出去，就导致'感冒'、口腔溃疡、各种炎症、各种湿性、油性、干性皮肤疾病、瘙痒、疼痛等器质性疾病，这些就是"未病"；人机体器官没有衰老，但身体虚，不能把各种代谢物代谢不出去，也可导致疾病的复发，这些也是"未病"。

Being stratified by gender factors, the CRC risk in females with homozygous W/W or Mx/W+W/W fast acetylators increased 2.47- and 2.13-fold compared to those with the Mx/Mx slow acetylator genotype (95% CI 1.27-4.82 for W/W genotype; 95% CI 1.17-3.89 for Mx/W+W/W genotype), however, the risk of the NAT2 genotype and CRC was not observed in males.

但在 W/Mx NAT2慢速代谢基因型与Mx/W+W/W快代谢基因型则无差异。若将性别分开分析时发现，女性具有NAT2 W/W homozygous 或 Mx/W+W/W快速代谢基因型发生大肠直肠癌的危险性是Mx/Mx慢速代谢基因型的2.47倍及2.13倍，但在男性则没有观察到 NAT2 基因型与大肠直肠癌的相关性。

In this review,we introduced the concept of protein turnover and the importance of its measurement.Both the direct and indirect methods were reviewed,and the compartmental analysis method was discussed in detail.

本文对蛋白质周转代谢的概念、术语、动物蛋白质周转代谢的意义做了阐述，介绍了蛋白质周转代谢的测定方法，并重点介绍了蛋白质周转代谢的随机分析与房室分析方法。

The multivariate logistic stepwise regression analysis showed that compared with individuals with no drinking milk,or no fish and aquatic product intake,or no drinking tea,or no sucrose intakes,the milk intakes 250-1500 g/week(OR=0.731,95%CI:0.542-0.987),the fish and aquatic product intake with 250-1000 g/week(OR=0.720,95%CI: 0.541-0.959),or sucrose intakes 250 g/month(OR=0.446,95%CI:0.255-0.779),drinking tea forepassed(OR=0.635,95%CI:0.458-0.883),and current (OR=2.084,95%CI:1.390-3.125) had different levels of risk on MS.

Logistic逐步回归分析结果提示，牛奶摄入、水产品摄入和饮茶是代谢综合征的保护因素，而年龄和糖摄入是代谢综合征的危险因素，其中牛奶摄入在250～1500 g/周(OR=0.731，95% CI=0.542～0.987)，水产品摄入在250～1000 g/周(OR=0.720，95% CI=0.541～0.959)以及以前饮茶（OR=0.446，95% CI=0.255～0.779和现在正在饮茶(OR=0.635，95% CI=0.458～0.883)，对代谢综合征的保护作用明显，而糖摄入250 g/月时代谢综合征的患病的危险是不食用食糖的2倍(OR=2.084，95% CI=1.390～3.125)。

When 2.0 g/L of malate was added to the fermentation medium, the metabolic flux of byproducts L-Ala and lactic acid decreased by 22.1% and 16.5%. At the same time, the metabolic channeled to EMP and glyoxyl circle decreased by 2.26% and 9.09%. However, the metabolic flux channeled to HMP increased by 2.26%.The metabolic flux channeled to the L-glutamic acid synthesis pathway increased from 73.59% to 79.92%.

在L-谷氨酸发酵中、后期添加2.0 g/L苹果酸后，合成副产物L-丙氨酸和乳酸的代谢流量明显减少，分别降低了22.1%和16.5%，EMP途径和乙醛酸循环的代谢流分别减少了2.26%和9.09%，HMP途径的代谢流增加了2.26%，而L-谷氨酸生物合成的代谢流从73.59%增长至79.92%，较未添加前提高了6.33%。

The mature egg cell was an inactive cell with only a few polysomes. At the early zygote stage, a large number of ribosomal precursors were produced by the nucleolus, and many polysomes appeared in the cytoplasm, which suggests a high level of metabolism. Zygote at the dormancy stage had a small nucleolus and marked decrease in ribosomes, as shown by a few polysomes, which suggests decreased metabolism. Zygotes in the prophase of mitosis and two-celled proembryo became active again in metabolism, for a prominent nucleolus, high density of ribosomes and increased number of polysomes in the cytoplasm.

结果如下：在成熟卵细胞中多聚核糖体数量不多，且细胞代谢活性较弱；初期合子内，核仁大量合成核糖体前体物质，胞质中多聚核糖体数目众多，细胞代谢活性较强；休眠期合子的核仁变小，胞质中核糖体数量急剧减少，仅有少量多聚核糖体，细胞代谢活性较弱；合子分裂前期和二细胞原胚期，核仁显著，胞质中核糖体的密度增加，出现大量多聚核糖体，细胞代谢活性较强。

In conclusion, the hepatotoxicity of clivorine is caused by the hepatotoxic pyrrolic metabolites formed in vivo. CYP3A involved in the formation of pyrrolic metabolites and plays a key role in metabolism-induced hepatotoxicity of clivorine.

Clivorine的肝毒性是其在体内形成的肝毒性吡咯代谢物所致，CYP3A参与了肝毒性吡咯代谢物的形成并在clivorine的代谢致毒方面发挥了关键性的作用，因此CYP3A的诱导剂和抑制剂可以影响肝毒性吡咯代谢物的形成，从而影响clivorine的肝毒性。

The major in vitro metabolites of clivorine found in the incubation mixture are two non-pyrrolic metabolites(M1 and M2) and the formation of hepatotoxic pyrrolic metabolites from clivorine is only the minor in vitro metabolic pathway of clivorine in female rats.

山冈橐吾碱在雌性大鼠肝微粒体内的主要代谢物为两个非吡咯代谢物M1和M2。与雄性大鼠不同，生成肝毒性的吡咯代谢物为其次要的代谢途径。

However, most experimental evidence is indirect and unassembled. In this paper the studies on LDH-C and energy metabolism of mammal spermatozoa were reviewed, We suggested that LDH-C played the multi-roles in energy metabolism of mammal spermatozoa, not only in directly the energy metabolism pathway but also in the signal pathway of spermatozoa.

综述了对哺乳动物精子能量代谢和LDH-C两个方面的研究，提出LDH-C在精子的能量代谢中扮演着多重角色，不仅直接参与精子的能量代谢，还可能参与哺乳动物精子获能的信号途径，LDH-C和哺乳动物精子的能量代谢密切相关。

The study showed the basic principle of C and N metabolism of spring maize, and indicated the enzyme differences of C and N metabolism of different spring maize varieties, and proposed the regulation effect of different N nutrition levels on C and N metabolism and the yield and quality of spring maize.

本研究首次将甜玉米、粘玉米、高淀粉玉米为试材，系统研究不同品质类型春玉米碳氮代谢机理，明确春玉米碳氮代谢基本规律，并在酶水平上探讨不同品质类型春玉米碳氮代谢的差异，揭示氮肥施用量对碳氮代谢及产质量的调控效应，为春玉米品质改良和高产、优质、高效栽培提供理论依据。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失