人类

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

Pattern designs in the layout of books can attach cultural information to abundant psychological tendencies and categorise the perceivability and visualization of patterns into the appreciation of words.

书籍装帧艺术，是一种客观存在的艺术形式，从古至今，在它不断演化变革过程中，始终离不开当时的历史条件，书籍利用文字、符号、图形记载着人类的思想和情感，它叙述着人类文明进程，传播人类文化。

Even studies of phylogenetically disparate species, such as songbirds, can suggest to us some things about what we humans are doing and, conceivably, how we might be doing them.

甚至是对那些在系统发生上和我们人类在本质上根本不同的动物的研究，比如对鸣禽的研究，也能够向我们揭示出一些关于&人类在做什么&和&人类是怎么做的&这样的信息的。

The idea took hold of the motive that had originated in the human building instinct and treated it plastically, creating an architectural form of society.

这种观念掌控着人类建筑的动机，而这种动机源于人类的本能，从而创造了人类社会的建筑形式。

They are willing unless they are tamed animals such as dog, cat, sheep, horse or cattle; otherwise, only stupid animals would like to come close to a polyphagous animal like mankind.

对此我也感到怀疑。除非他们是狗、猫、羊、马、牛等人类所饲养的动物，否则以人类杂食性的特质，也只有傻瓜才会与人类保持过度亲近的。

They are willing unless they are tamed animals such as dog, cat, sheep, horse or cattle; otherwise, only stupid animals would like to come close to a polyphagous animal like mankind.

对此我深感怀疑。除非它们是狗、猫、羊、马、牛等人类所饲养的动物，否则以人类杂食性的特质，也只有傻瓜才会与人类保持过度亲近的关系的。

This puzzledom is not only the urban's puzzledom, but the human's.

但是我们应该看到，人类与城市之间的和谐永远是一种动态的生成；它孕育在我们人类与城市的现实之中，孕育在我们人类与城市所产生的诸问题之中。

Pigs have infected people with mixed-up viruses before, even triple whammies made of pig, bird and human flu genes, Richt's paper shows.

里希特的论文表明，猪早就把混合病毒传染给了人类，甚至用猪、禽和人类病毒基因的三重混合沉重地打击了人类。

The being-established of socialist market economy system bothreflects that the necessary claiming of the economic social conditions inthe present China and the correct choice done by C.P.C after summarizing theexperiences and chide of history.The socialist market economy is thehistorical sublation to the capitalist market economy and represents thefuture of the market economy.The development of socialist market economyembodies the inevitable history trend of the mankind pursuing thecivilization and evolution.The practice of the socialist market economy willbe open a new way for the underdeveloped socialist countries to accomplishtheir modernization and provides a mode for the developed capitalistcountries to sublate the abuse inside their capitalist institute.

从社会形态历史演变的角度看，社会主义市场经济形态，是对资本主义市场经济形态的历史扬弃，代表市场经济的未来和明天，它的出现和发展体现着人类追求进步和文明的历史必然趋势，它的实践为不发达的社会主义国家如何进行现代化建设开辟一条了正确的道路，也将为资本主义市场经济国家扬弃制度弊端提供一种示范，所以，从某种意义上讲，它是人类文明进程中所出现的新形态，开辟了人类通向&自由王国&的历史新道路。

Each unit of the ascendant life is a veritable training school for the stage of existence just ahead, and this is true of every stage of mans progressive Paradise ascent; just as true of the initial mortal experience on an evolutionary planet as of the final universe headquarters school of the Melchizedeks, a school which is not attended by ascending mortals until just before their translation to the regime of the superuniverse and the attainment of first-stage spirit existence.

是一所为了超越实体阶段真正训练每个个体生命上升的学校，并且这是每个人真正进步上升至天堂的舞台；正象最初的人类在一颗进化的行星上真实的体验，正如麦基冼德宇宙学校总部，一所学校不是从事人类上升的直到先前他们的改变只是人类过分的政治制度和达到精神生活的初级阶段。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。