产生细菌的

As the time went by, there are more increase in the severity of the stromal collagen destruction, the more outspreading pattern and proliferation occurred in bacteria activity, and more abundant substance with auto-fluorescence within the cornea.

随著注射后的时间增加，角膜基质的胶原蛋白被破坏的程度也显著的增加，细菌也有增殖的趋势以及向周围散落蔓延，并且在角膜内有大量的自发萤光物质产生。

According to the domain organization, the GGDEF-EAL containing proteins (pfam database, version 17.0) were classified into A and B types. Six hundreds and five of the 621 proteins were in A type, which was also found in the ancient bacteria Aquifex aeolicus VF5 suggesting that this is the ancestor of the GGDEF-EAL proteins. Phylogenetic analysis of GGDEF- and EAL- containing proteins in the genome of V. vulnificus YJ016 revealed that GGDEF-EAL proteins were clustered. Comparative analysis of domain organization of the clads in the EAL tree allowed identification of several duplication events. The results indicated that most of the GGDEF- and EAL- containing proteins arised by gene duplication.

根据pfam资料库(Version 17.0)，我们整理同时拥有GGDEF和EAL功能性区域的蛋白质，这些蛋白质可以被区分成两种型态，在总数621个GGDEF-EAL中有高达606个是A型态，而且它在古老的细菌Aquifex aeolicus VF5的基因体中也能找到，因此我们推测它可能是GGDEF-EAL的袓先，藉由分析创伤弧菌中所包含之GGDEF和EAL的演化关系，大部份的GGDEF-EAL会群聚在树型相近的位置，进一步比较在EAL树型上有邻近关系的蛋白质序列，根据他们的长度、与所包含的功能区域，我们找到了一些重制的演化痕迹，这样的结果指出，目前看到大多数的GGDEF 和EAL可能都是经过重制产生。

This Program Project is composed of five projects and an administrative core unit. The specific aims of Project 1 are to study the roles of SPE B, SPE A, M protein and NADase to correlate with bacterial virulence and disease severity in different clinical spectra of GAS infections. We will also study the pathogenic factors of a unique virulent clone of Ml strain caused dominant invasiue GAS disease in Taiwan in the past two years. The effects of penicillin and clindamycin on the production of SPE A and SPE B will also be determined.

本群体计画包含有5个子计画及一个行政核心计画，第一子计画的目标在於研究热原性外毒素A，B和M蛋白及NADase在A群链球菌感染中的功能及其与细菌致病力、疾病严重性的相关性，同时将针对一株最近在台湾造成侵犯性较强的A群链球菌菌株研究其致病因子的异同，并将探讨抗生素penicillin及clindamycin对於热原性外毒素A及B产生的影响。

Growing Low-Oxygen Zones in Oceans Worry Scientists [Mar 7] In some spots off Washington state and Oregon, the almost complete absence of oxygen has left piles of Dungeness crab carcasses littering the ocean floor, killed off 25-year-old sea stars, crippled colonies of sea anemones and produced mats of potentially noxious bacteria that thrive in such conditions.

&海洋上不断增长的低氧气区域令科学家们担心&（3月7日）。在沿着华盛顿州和俄勒冈州的某些地方，几乎整个地缺乏氧气，导致成堆的Dungeness螃蟹的尸体散落在海底，使25岁的大的海星死亡，毁坏了海葵生活的群落，产生了大簇在此条件下兴盛的，具有潜在毒性的细菌。

Growing Low-Oxygen Zones in Oceans Worry Scientists [Mar 7] http://news.yahoo.com/s/mcclatchy/20100307/sc_mcclatchy/3444187 In some spots off Washington state and Oregon, the almost complete absence of oxygen has left piles of Dungeness crab carcasses littering the ocean floor, killed off 25-year-old sea stars, crippled colonies of sea anemones and produced mats of potentially noxious bacteria that thrive in such conditions.

&海洋上不断增长的低氧气区域令科学家们担心&（3月7日） http：//news.yahoo.com/s/mcclatchy/20100307/sc_mcclatchy/3444187 。在沿着华盛顿州和俄勒冈州的某些地方，几乎整个地缺乏氧气，导致成堆的Dungeness螃蟹的尸体散落在海底，使25岁的大的海星死亡，毁坏了海葵生活的群落，产生了大簇在此条件下兴盛的，具有潜在毒性的细菌。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。