亡

Objective To investigate the expression of survivin in thyroid carcinoma and its relationship with vascular endothelial growth factor expression.

目的探讨细胞凋亡抑制因子存活素在甲状腺癌中的表达效应及其与血管内皮生长因子表达的关系。

MMP expression and activities were studied in macrophages after engulfment of apoptotic cholangiocytes in vitro.

我们在体外研究巨噬细胞吞噬凋亡胆管细胞后MMP的表达及活性变化。

Apoptotic eosinophils were added to A549 cells which was pretreated with dexamethasone or RU38486 for engulfment .

将凋亡的嗜酸粒细胞加入到预先用地塞米松或RU38486处理的A549细胞中进行吞噬。

In vitro assay showed that engulfment of apoptotic spermatogenic cells increases ATP production by Sertoli cells.

体外实验证实吞噬凋亡生精细胞能够促进Sertoli细胞产生ATP。

The exposure of phosphatidylserine at the cell surface plays a critical role in blood coagulation and serves as a macrophage recognition moiety for the engulfment of apoptotic cells.

细胞表面磷脂酰丝氨酸的暴露在血液凝固中起到关键的作用，而且它可以作为巨噬细胞对凋亡细胞加以吞噬时的识别部分。

After engulfment apoptotic eosinophils were stained for peroxidase with o-dianisidine and A549 cells were stained with haematoxylin.

吞噬结束后，凋亡的嗜酸粒细胞用邻联茴香胺进行过氧化物酶染色，A549细胞用苏木素加以胞核衬染。

In addition, the mitochondria showed no signs of swelling and the nuclear membrane remains intact. Multiple membrane-bound apoptotic bodies and engulfment of cell debris and corpses by phagocytes were observed at 24h, while extensive cell loss appeared at 48h. These results demonstrated the occurrence of high level of apoptosis by 24h postdosing.

相应的超薄切片在电子显微镜下得到结果与光镜下一致，24h前线粒体形态结构无明显变化，主要有染色质浓缩、边集及分割，以及内质网空泡化和凋亡小体的形成；24h后可观察到线粒体的肿胀和扩张，细胞发生崩解和死亡。

Appropriate clearance of apoptotic cells is an important step of programmed cell death. Although genetic and biochemical studies have identified several genes that regulate the engulfment of cell corpses, how these are degraded after being internalized in engulfing cell remains elusive.

中科院遗传与发育生物学研究所杨崇林课题组以秀丽线虫为模式研究程序性细胞死亡，通过遗传分析、基因表达、蛋白定位等实验手段，发现vps-18基因在凋亡细胞的降解过程中发挥重要作用。

Changdong" showed a noticeable enhancive effect when it was co-administrated with other anti-tumor agents or when it was co-applied with radiotherapy. The action mechanism study showed that an apparent cytotoxic effect of "Changdong" on ten tumor strains in vitro with a quantity-effect relationship was observed. Immunity experiment showed that "Changdong" could induce proliferation of spleen lymphocyte in mice bearing tumor and could improve NK cell" s activity, whereas has no impact on IL-2" s reproduction. It was also noticed that "Changdong" could induce human liver cancer QGY" s apoptosis in vitro, and it happened mainly on G0-G1 phase.

结果："长动"对小鼠移植瘤模型和人体肿瘤裸鼠异种移植均有明显抑制作用，量效关系明显："长动"与放疗和化疗分别联合应用有明显的增效作用：作用机制研究结果：细胞毒性试验研究表明"长动"在体外对10株肿瘤细胞有明显的细胞毒性作用，量效关系明显；免疫学试验表明"长动"可以诱导荷瘤小鼠的脾淋巴细胞增殖，增强NK细胞的活性，对IL-2的产生无明显影响；"长动"在体外可明显诱导人体肝癌QGY细胞凋亡，使细胞阻滞于G0-G1期。

Five models were used to investigate the "Changdong"" s anti-tumor effect: mice S180 sarcoma solid model, mice liver cancer H22 solid model, mice Lewis lung cancer model, as well as human liver cancer QGY and colon cancer LOVO implanted in naked mice; mice liver cancer H22 was also used to evaluate the enhancive effect of "Changdong" when it was co-applied with other anti-tumor agent or with radiotherapy; The "Changdong"" s cytotoxic effect in vitro on such tumors as QGY, LOVO, lung cancer A549, breast cancer MCF-7, as well as mice leukemia P388 was observed through MTT method. And investigate the effect of "Changdong" on proliferation of spleen lymphocyte, on activity of NK cell and on synthesis of IL-2 in mice bearing Lewis lung cancer, respectively. With propidium iodide straining, cell aigptosis and cell circle were analyzed by flow cytometry. Result:"Changdong" has an evident tumor inhibitive effect on mice tumor model as well as human tumor implanted in naked mice with a quantity-effect relationship.

使用小鼠S180肉瘤、小鼠肝癌H22实体瘤和小鼠Lewis肺癌模型，以及人体肝癌QGY和人体肠癌LOVO裸鼠异种移植模型，进行"长动"的抗肿瘤药效学研究：用小鼠肝癌H22进行"长动"合并放疗和化疗的增效作用研究；用MTT法进行"长动"对肝癌QGY、肠癌LOVO、肺癌A549、乳腺癌MCF-7、小鼠白血病P388等10株人体和动物肿瘤细胞的体外细胞毒性作用研究；用淋巴细胞转化试验、小鼠NK细胞活性试验、小鼠胸腺细胞增殖法分别测定"长动"对荷Lewis肺癌小鼠的脾淋巴细胞增殖的影响、自然杀伤细胞活性的影响和对小鼠产生白介素-2(IL-2)的影响；用流式细胞仪PI单染色法进行"长动"对人体肝癌QGY细胞的体外诱导凋亡作用和对肿瘤细胞周期的影响的研究。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。