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Methods:To produce antihuman DR5 monoclonal antibody(mDRA6) by immunizing BALB/c mice using DR5 protein. The change of DR5 expression after DDPtreated on HL60 cells was detected by FACS. Morphologic changes of HL60 cells were observed under fluorencence microscope. Cytotoxic and apoptotic effects of mDRA6 and DDP on HL60 cells were measured by MTT analysis. DNA fragmentation was detected by agarose gel electrophoresis.

DR5蛋白免疫BALB/c小鼠,融合筛选抗DR5杂交瘤细胞,制备抗DR5单抗——mDRA6;流式细胞术测定顺铂对HL60细胞表面DR5表达及细胞凋率;荧光显微镜下观察mDRA6与顺铂协同作用下HL60细胞形态变化;MTT法测定不同浓度的顺铂与mDRA6对HL60细胞存活的影响;琼脂糖凝胶电泳检测mDRA6与顺铂联合对HL60细胞DNA片段化的影响。

aim: to explore the therapeutic effects of antimonials on solid tumor by observing the effects of potassium antimonyl tartrateon the proliferation and apoptosis of human gastric cancer sgc 7901 cells in vitro.

目的:通过观察酒石酸锑钾在体外对人胃癌sgc 7901细胞增殖和凋的影响,探讨重金属锑剂对实体瘤的治疗作用,为pat用于临床治疗胃癌提供实验依据及理论基础。

Objective This study investigated the possiblitity that the antirheumatic effect ofhydroxychloroquine may be achieved by up-regulation of apoptosis.

目的研究活动期系统性红斑狼疮患者外周血单个核细胞在不同浓度羟氯喹体外培养下细胞凋的情况。

These data also suggest that PDCD5 may serve as a therapeutic target to enhance sensitivity to antirheumatic drug-induced apoptosis in RA.

因此,我们认为PDCD5可能参与了类风湿性关节炎的发病过程,可增强抗风湿药物诱导的凋的敏感性,从而成为新的治疗靶点。

The expression of Bcl-2 and Bax expression was revealed immunocytochemically using the antiserum against Bcl-2 and Bax.

Bcl-2原癌基因蛋白是位于线粒体膜、核膜及溶酶体膜的膜蛋白,可抑制细胞凋

Nourishing Yin Antitoxic Capsule ; glucocorticoids ; Yin deficiency syndrome ; apopotic ; TNF α; rat

养阴抗毒胶囊;糖皮质激素;阴虚证;细胞凋;肿瘤坏死因子α;大鼠

To study effects of the velvet antler polypeptides on spinal nerve cell apoptosis induced by β-amyloid peptide.

[目的]探讨鹿茸多肽对β-淀粉样蛋白诱导脊髓神经元细胞凋的保护作用。

Apolipoprotein D is a member of the lipocalin family. ApoD can bind small hydrophobic molecules such as cholesterol and arachidonic acid, etc. It also plays a role in many physiological and pathological processes such as development and differertiation of embryo, apoptosis of cancer cells, immune defense, and so on.

载脂蛋白D属于脂蛋白家族,和该家族的其它成员一样,其基本功能是转运一些脂类的小分子物质,还参与胚胎的发育、分化;肿瘤细胞的发生、发展和凋;免疫性反应;抵抗外界环境胁迫以及神经系统的发生和损伤修复。

He said in his dream he saw the apparition of his dead wife.

他说在梦中他看见了他妻的幽灵。

She claimed to have seen the apparition of her dead husband.

她声称看到过夫的幽灵。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。