亡

Nix-induced cardiomyocyte apoptosis is a major determinant of adverse remodeling in pathological hypertrophies, a finding that suggests therapeutic value for apoptosis inhibition to prevent cardiomyopathic decompensation

在病理性心肌肥厚中，Nix诱导的心肌细胞凋亡是恶性重塑的主要决定因素，从而提示抑制凋亡在阻止心肌病失代偿中的治疗价值。

The process is regulated by a large family of proteins that either promotes or inhibits cell death.

凋亡过程受到一大类蛋白质的调控，或者是促进或者是抑制凋亡。

The Food and Drug Administration of USA hasapproved the use of this topical medicine for treatment of different malignant andpremalignant tumors such as actinic keratoses and basal cell carcinoma. Althoughimiquimods exact mechanisms of action in neoplastic diseases has not yet been fullyelucidated, animal and human studies have shown its ability to enhance the productionof cytokines such as interferon-, interleukin-12, and tumor necrosis factor- though conjugations with Toll like receptors on the surface of dendriticcells of the monocyte-macrophage lineage.

有关咪喹莫特抗癌作用的具体机制仍不十分明了，一般认为，咪喹莫特主要是通过与免疫相关细胞表面的Toll样受体结合、促进IFN-α、TNF-α、IL-12等多种前炎症细胞因子的分泌，进而激活天然与获得性免疫反应的方式发挥抗癌作用；进一步的研究发现，咪喹莫特尚能选择性的抑制某些皮肤肿瘤细胞的增殖并诱导其凋亡，提示增殖抑制和诱导凋亡可能是评价咪喹莫特抗肿瘤作用的重要指标和机制。

In a-bout one third cells agglomerate chromatin localizes at the edge of nucleus, which shows apoptotic traits.

PCF处理的HaCaT细胞的超微结构损伤程度明显减轻，如胞浆内更少的空泡样结构和更多形态正常的细胞器，少见具有凋亡形态的细胞，未见凋亡小体等。

In Chapter Two, some methods such as electron microscope, DNA ending label and MTT measurement were used to studied the changes of apoptosis, necroses and cell vigour of leukaemia K562 cell trunk and HL-60 cell trunk irradiated with millimeter wave. Different effects of millimeter wave to leukaemia cell trunks and human marrow cells were observed clearly. Human marrow cells were not so sensitive to millimeter wave radiation as leukaemia cells.

第二章，利用电镜技术、DNA末端标记、MTT活力测定等方法，研究了毫米波对红白血病K562细胞株、人类急性早幼粒白血病细胞株HL-60及正常人骨髓单核细胞的细胞超微结构、细胞凋亡、细胞活力的影响，结果发现毫米波辐射对正常人骨髓细胞及白血病细胞的影响明显不同，正常人骨髓细胞所受影响较小，特别是功率密度小的毫米波对其无影响；而白血病细胞受辐射后发生显著的凋亡或坏死，细胞活力显著下降，该效应具有明显的功率窗和时间窗。

Objective: It has been proved that apoptosis obeys some laws and orders.

目的：细胞凋亡是按一定规律和程序进行的，许多因素均可诱导细胞凋亡。

Objective: The purpose of this study was to determine whether potentiating induction of apoptosis in cervical cancer cell line SiHa lacking full-length FHIT transcripts and endogenous FHIT protein by cisplatin via introduction of extopic FHIT gene. Meanwhile, to investigate if the apoptosis of the SiHa cells is induced by FHIT gene.

目的 验证外源性脆性组氨酸三联体抑癌基因的导入是否诱导宫颈癌SiHa细胞凋亡，观察FHIT导入与顺铂联合应用诱导宫颈癌SiHa细胞凋亡的作用是否有协同效应，为联合基因治疗和化疗药物治疗人宫颈癌提供实验依据。

On the day when a novice makes her profession, she is dressed in her handsomest attire, she is crowned with white roses, her hair is brushed until it shines, and curled. Then she prostrates herself; a great black veil is thrown over her, and the office for the dead is sung.

初学生到了发愿的日子，大家尽量把她打扮得整整齐齐，替她戴上白蔷薇，润泽并蜷曲她的头发，接着她伏在地上，大家替她盖上一大幅黑布，唱起悼亡的诗歌，举行度亡的祭礼。

On the day when a novice makes her profession, she is dressed in her handsomest attire, she is crowned with white roses, her hair is brushed until it shines, and curled. Then she prostrates herself; a GRE at black veil is thrown over her, and the office for the dead is sung.

初学生到了发愿的日子，大家尽量把她打扮得整整齐齐，替她戴上白蔷薇，润泽并蜷曲她的头发，接着她伏在地上，大家替她盖上一大幅黑布，唱起悼亡的诗歌，举行度亡的祭礼。

On the day when a novice makes her profession, she is dressed in her handsomest attire, she is crowned with white roses, her hair is brushed until it shines, curled. Then she prostrates herself; a great black veil is thrown over her, the office for the dead is sung.

初学生到了发愿的日子，大家尽量把她打扮得整整齐齐，替她戴上白蔷薇，润泽并蜷曲她的头发，接着她伏在地上，大家替她盖上一大幅黑布，唱起悼亡的诗歌，举行度亡的祭礼。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。