亡

However, fully consideration of special structure and physiological function of CRP is critical to investigate whether CRP provide protect effect or pathogenic effect in the progression of atherosclerosis. CRP is a member of pentrxins family, which consists of five identical, noncovalently associated 23-kDa protomers arranged symmetrically around a central pore with a 102 A external diameter. Each protomer has a recognition face with a phosphocholine binding site consisting of two coordinated calcium ions adjacent to a hydrophobic pocket. The opposite face of the pentamer is the effector face, where complement Clq binds and Fc receptors are presumed to bind. A cleft extends from the center of the protomer to the central pore of the pentamer. Both faces ofpentamer form a special bi-phase structure: one face is the ligand recognition phase, which can recognize apoptosis cells and enzyme modified low density lipoprotein in which PCh is exposed.

CRP是一种五聚体蛋白，外径为102 A，由5个相同的单体以非共价键结合，形成双面的环形结构，每个单体的配体识别位点或受体结合位点分别位于五聚体两个平面上，分别组成配体识别相和效应器相，从而构成特殊的二相性结构：一面为配体识别相，含有磷酸胆碱(phosphorycholine，PCh)结合位点，能够使CRP识别在病理条件下暴露出PCh的凋亡细胞、酶修饰低密度脂蛋白(enzyme modified low density lipoprotein，E-LDL)等。E-LDL是天然低密度脂蛋白(native Low density lipoprotein，N-LDL)在多种蛋白酶，如胰蛋白酶、神经氨酸酶、胆固醇酯酶等作用下的代谢产物，其主要特点是结构发生改变(N-LDL大小均匀，平均直径250±30 A，E-LDL大小差异极大，直径为100-2000 A)，暴露磷酸胆碱位点，能够被CRP识别；另一面为效应器相，能够与巨噬细胞、单核细胞表面受体FcγRⅡa结合，介导巨噬细胞、单核细胞识别及吞噬凋亡、坏死细胞作用。

Objective To observe the characteristic of apoptosis in the largeintestinal carcinomas and adenomas and assess the significance of apoptosis in it.

目的 观察大肠癌和腺瘤组织细胞凋亡的特征，探讨细胞凋亡和增殖在大肠癌和腺瘤组织中的意义。

Catechines have an effect of inducing apoptosis of LoVo cells,which is antagonized by cycloheximide and zinc sulfate.

儿茶素能诱导大肠癌LoVo细胞的凋亡，这种凋亡作用能被放线菌酮或硫酸锌所拮抗。

Again and again he chides his readers for overestimating the importance of famous British and American battles in the West and overlooking much larger ones on the eastern front: more than 2m Germans were killed in the east, over ten times the number who died fighting in the west.

他再三地指责读者过高地评价了西部有名的英国和美国战场而大大地忽视了东部阵线：200多万德国人在东部战亡，比在西部战亡的人数多了近十倍。

HAX-1 is not the only anti-apoptotic protein that is cleaved and inactivated by Omi during cell death.

HAX-1是一种凋亡过程中被OMI酶切和灭活的著名的抗凋亡蛋白。

The cochleae of animals were dissected. propidium iodide, a dna intercalating fluorescent probe, was used to trace the morphological changes in ohc nuclei. f-actin staining was used to determine missing ohcs. the single strand dna in apoptotic ohcs of guinea pigs and mice, and apoptosis inducing factor and endonuclease g in ohcs of guinea pigs were examined by immunofluorescence method.

分离解剖耳蜗后，用碘化丙啶染色细胞核、pholloidin染色f-actin，免疫荧光抗体分别染色单链dna、核酸内切酶g和凋亡诱导因子（apoptosis inducing factors， aif），制备耳蜗铺片，激光共聚焦显微镜下观察凋亡和坏死毛细胞内的荧光信号变化。

Fluorescence were conglomerated like grain on the cell nucleus. Many cell nucleus shrank or distorted. Apoptotic little substance appeared.

对照组、Rh2组和DDP组的细胞无明显凋亡峰，而Rh2+DDP组则出现了显著的凋亡峰。

CO2 can inhibit the proliferation and promote the apoptosis of the endometrial cancer cells with distending pressure from 40 mmHg to 100 mmHg. The higher the pressure is, the more obviously CO2 can inhibit the proliferation and promote the apoptosis of the endometrial cancer cells.

二氧化碳在40~100 mmHg压力范围内，能够抑制子宫内膜癌细胞的增殖，促进子宫内膜癌细胞的凋亡，且随着压力的增加，二氧化碳对子宫内膜癌细胞增殖抑制和促进凋亡作用愈明显。

For her intermingled with a deep sense of regret over her death and the squandering of their love, an emotion that has not been often depicted in former elegies.

诗人在诗中表达了对亡妻的眷恋，对往昔爱情的追忆，以及对逝去时光的懊悔，显露出诗人自责的情绪，为现代悼亡诗引入了悔恨的情愫。

Flow cytometry analysis showed that the 1% and 2% of lactic acid bacteria fermentation filtrates induced the apoptosis of Hela cells at 48 h and 72 h, while the 5% of the filtrate induced the apoptosis at 24 h, 48 h and 72 h, respectively.

流式细胞仪分析，1%、2%的乳酸杆菌DM9811发酵滤液在48、72h可诱导Hela细胞凋亡；5%的乳酸杆菌发酵滤液在24、48和72h均可诱导Hela细胞凋亡。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。