亡

A 30 min exposure to peroxynitrite (10〓μmol/L) followed by incubation in fresh medium induced apoptosis in cultured cerebellar granule cells, which was confirmed by DNA laddering, chromatin condensation, nuclei fragmentation, and the formation of apoptotic bodies.

原代小脑颗粒细胞经10μmol/L过氧化亚硝基处理30min，并继续培养一定时间后逐渐发生细胞凋亡，主要表现为DNA链断裂、染色质凝缩、核破裂、形成凋亡小体。

We may well explain why ricin-induced apoptosis showed no typical DNA ladder. The presence of laddering in DNA gels implies an apoptosis process, but its absence does not rule out the apoptosis. The ricin 0.05μmol〓 had no effect on the 〓 phase of cell cycle, but induced 〓 arrest. The ricin may affect the balance of synthesis and destruction of proteins that controlling the cell cycle.

检测到DNA梯度表明细胞发生了细胞凋亡，未检测到DNA梯度不能否认凋亡的存在。0.05μmol.L〓的蓖麻毒素对HeLa细胞周期的G〓/G〓期无影响，而诱导了G〓/M期阻滞，蓖麻毒素可能引起一些控制细胞周期蛋白的合成与降解发生紊乱。

After 4 days of serum deprivation, CPR-293 cells exhibited substantial nuclear condensation and fragmentation DNA laddering but HO-1/CPR-293 cells was not apparent. Thus HO-1 expression is sufficient to protect cells from serum deprivation-induced apoptosis. In the experiment, we used primary cultures of from HO-1 fibroblasts and their wild-type littermates fibroblasts CPR-293 cell and HO!

2生理加压诱导细胞凋亡我们用稳定的CPR细胞株和HO1和CPR在一起的细胞株实验，当浆液丢失4天后，CPR-293细胞表现出有实质的核浓缩和DNA梯状条带的形成，而HO1/CPR-293细胞则没有，显示HO1是充分保护细胞，避免在浆液丢失情况下而诱导的细胞凋亡。

In the other hard, it is reported that caspase - 3 has important effect in cell apotosis by destroyiny the cell anti - apoptosis factors ( eg: bcl - 2 ), cell framework (eg: frame protein actin, fodrin, lamin).

此外文献报道，CasPase一3还通过破坏细胞抗凋亡因素(如bel一2)，破坏细胞的结构(如结构蛋白aetin、fodrin、larnin)在细胞凋亡中发挥作用。

A coronary microthromhoembolism model was successfully established by injecting sodium laurate into the coronary arteries. Coronary micro-thrombogenesis may promote the apoptosis of cardiomyocytes, and is one of the reason for heart function decrease. Telmisartan can efficiently suppress ventricles reconstruction, improve heart function, and inhibit the apoptosis of myocardial cells after microthrombogenesis in coronary artery.

冠状动脉内注射月桂酸钠能够成功建立冠状动脉微血栓的模型；冠脉内微血栓增加心肌细胞的凋亡，是导致心功能下降的原因之一；替米沙坦能有效地抑制心脏重塑，改善心功能，并能抑制冠脉微血栓后心肌细胞的凋亡。

Result:(1)Tau prevented neurons against Mn toxicity of low and middle concentrations. The ideal conditions can reach upon 4. 5 mM Tau added just, nearly no apoptosis cells could be detected.(2)The percentages of apoptosis intogether were lower than those in Mn just , being concentration-dependent relations with Taurine levels.(3)Mn induced DNA damage of neurons with dose-depedent, The higher of Mn concentration, the lengther of the comet tail and the higher percent comet-like cells. Tau incubated could weaken significantly the lesions of Mn towards DNA on the degree.

结果：(1)牛磺酸对中低剂量锰的毒性有一定的拮抗作用，单独加入牛磺酸效果最好剂量是4.5mM，视野下几乎不见凋亡细胞；(2)牛磺酸干预后培养神经细胞凋亡率低于相同剂量的单纯锰培养细胞组，且与牛磺酸浓度呈剂量依赖性；(3)锰引起培养神经细胞DNA损伤，表现在彗星尾长增加，彗星样细胞百分率增加；加入牛磺酸干预后，可明显改善锰造成的培养神经细胞DNA损伤。

In no alteration of HIF-1αprotein, nitric oxide donors, metavanadate and sodium nitroprusside, significantly abrogated DFO-induced apoptosis.

4一氧化氮(Nitric Oxide， NO)供体——钒酸钠(Sodium Metavanadate， vanadate)和硝普钠(Sodium Nitroprusside， SNP)都能够抑制DFO诱导的白血病细胞凋亡，但对CoCl2诱导的细胞凋亡没有抑制作用。

These results had proved that the Morinda can selectively induce the cell lines' apoptosis, and the Rosa can induce more cell lines' apoptosis.

这些结果提示诺丽汁对肿瘤细胞的促凋亡作用具有一定的选择性，刺梨汁对的促凋亡作用范围较广。

When the cells were exposed to 10 nmol/L taxol for 24 h,significant cell-cycle arrest was also observed by fluorescence microscope,coexisting multinucleated cells were found as well.

随着作用时间延长，〓期阻滞增强，凋亡细胞百分率也随之增高，凋亡的出现滞后于有丝分裂阻滞，其峰值亦滞后于细胞周期阻滞的峰值。

In IUGR newborns, the expression levels of WT1 and Bcl-2 protein were significantly decreased, and their immunostaining were also suppressed in the nephrogenic zone. Conclusions Reduction of nephron number in IUGR rat may be associated with enhanced apoptosis in kidney development.

IUGR大鼠肾单位数目减少可能与肾发生中细胞凋亡增加相关，而WT1、Bcl-2表达减少，Bcl-2/Bax比例降低可能是细胞凋亡增加的分子机制之一。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。