亡

Objective To observe the pathological changes and investigate the hepatocyte apoptosis relating with CYP2E1 in alcoholic liver diseaseof rat. Method the Model of Alcoholic liver Disease: Rats were randomly divided into model group(n=37)and control group(n=33). The dose of 40％ethanol was administerd at 8g/kg body weight by garage twice daily for 8 weeks in model group, and control group was received isovolume saline by gavage. End of 8th week, the activities of serum ALT and AST were detect by autobiochemistry instrument. The pathological changes of liver was observed under light microscope after HE staining, hepatocyte apoptosis was detected by the TUNEL method.

目的： 研究酒精性肝病细胞凋亡程度与细胞色素P4502E1表达的关系方法：用酒精灌胃法制备大鼠酒精性肝病模型，将70只wistar大鼠随机分为正常对照组(33只)和酒精灌胃组(37只)，连续灌胃8周后病理切片观察细胞凋亡程度，干化学法测定ALT、AST的含量变化，用PCR法测定细胞色素P450 2E1的表达变化。

Purpose: Study the mechanism of tumor cells apoptosis induced by Agaricus blazei Polysaccharid, and the effect of P53, Caspase-3 and P16 genes in this inducing process otherwise.

目的研究巴西蘑菇多糖诱导肿瘤细胞凋亡的作用机制，并进一步研究P53、Caspase.3和P16等3个基因在此凋亡过程中的作用。

Anergic T cell was gradually apoptic in vitro Fas/Fasl interaction participated in the apoptosis.

无能T细胞在体外是逐渐发生凋亡的，Fas/FasL参与细胞凋亡过程。

The signal transduction involved in the cold-induced apoptosis is anfractuous, either mediated or modulated by reactive oxygen species, Ca~(2+), Fe~(2+) and cold-relevant genes in vivo.

冷诱导细胞凋亡的信号转导过程错综复杂，细胞内活性氧自由基、Ca~(2+)、Fe~(2+)以及冷相关基因都介导或调控冷引起的细胞凋亡。

To investigate the stantant changes of Ⅰ、Ⅱ、Ⅲ and PG expression of mandibular condylar chondrocytes stimulated by the different static compressive stresses, so that to make a primary understanding of the relationship between the differentiation and dedifferentiation of condylar chondrocytes and different compressive stresses; to investigate the stantant changes of the content of DNA of mandibular condylar chondrocytes stimulated by the different static compressive stresses, so that to make a primary understanding of the relationship between proliferentiation and apothesis of MCCs and different static compressive stresses.

观察单层培养的髁状突软骨细胞加载不同静压力后，Ⅰ、Ⅱ、Ⅲ型胶原以及蛋白多糖表达的变化，探讨不同静压力对髁状突软骨细胞的分化及去分化的即时效应；观察单层培养的髁状突软骨细胞加载不同静压力后，其增殖、凋亡及细胞周期的变化，探讨不同静压力对髁状突软骨细胞增殖及凋亡的即时效应。

Methods: 1. Male Sprague-Dawley rats were established renal calcium oxalate calculi model. 2. The different dose of LBP, medlar soak and apozem was given. The calcium oxalate crystallization, the renal cell apoptosis and the renal free radical level were detected. 3. The relationship of the renal cell apoptosis index, the renal free radical level and the calcium oxalate crystallization grade in the kidney tubule was determined.

1、给大鼠建立肾草酸钙结石模型；2、予以不同剂量的枸杞多糖，不同浓度的枸杞浸泡剂和煎剂灌喂，比较肾小管内草酸钙结晶的形成，测定肾小管上皮细胞的凋亡指数，自由基水平；3、分析结晶等级评分、细胞凋亡指数和自由基的相互关系，判断枸杞多糖预防肾草酸钙结石的作用机制和效果。

Methods Ovarian GC DNA fragments of both atretic and developing follicles before and after estrogen (1 μg/ml), androgen (1 μg/ml) treatments were analysed by agarose gel electrophoresis. The expression of bcl-2 mRNA was also determined by northern blotting in GC of developing follicle after sex steroids addition. Results Internucleosomal DNA cleavage occurred in granulosa cells in atretic follicles and after androgen treatment.

应用细胞培养、选择性DNA抽提和琼脂糖凝胶电泳技术分析闭锁卵泡和发育中卵泡颗粒细胞的凋亡状况，及雌激素(1 μg/ml)、雄激素(1 μg/ml)对体外培养发育中的卵泡颗粒细胞凋亡的作用；用Northern印迹杂交技术检测经雌、雄激素刺激后发育中的卵泡颗粒细胞bcl-2基因mRNA表达的变化。

(1)Both the liver regeneration and apoptosis are influenced by conspicuous bilirubinemia, hepatectomy and hepatic artery resection in rats after obstructive jaundice, especially by the liver resection volume and conspicuous bilirubinemia.(2) Under the condition of conspicuous bilirubinemia, the influence of 70% PH with HAR on liver regeneration and apoptosis is severer than its counterpart of 42% in the rats. Thus, the former is not safe and should be avoided and the later can be used.

高胆红素血症时，肝切除量是影响大鼠肝切除联合肝动脉切除实施安全性的重要因素，42%肝切除联合肝固有动脉切除、胆肠再通内引流，对肝细胞再生和凋亡影响较小，安全可行；70%肝切除联合肝动脉切除、胆肠再通内引流后肝细胞再生显著受抑制，凋亡增多，死亡率高，应避免实施。

Results The number of cellular apoptosis was obviously increased in multiple organs from the six patients died from SARS. The cellular apoptosis occurred predominantly in cytokeratin-positive pneumoncytes, terminal bronchiolar epithelium, CD3 + and CD8 + lymphocytes, as well as a part of CD20 + lymphocytes and CD68 + macrophages.

结果 与正常组织比较，SARS患者全身多器官组织细胞凋亡数目明显增多，尤以肺脏和免疫器官为甚，主要的凋亡细胞类型为CK阳性肺泡上皮细胞、终末支气管黏膜上皮细胞、CD3+细胞、CD8+细胞，以及少部分CD2 0 +细胞和CD6 8+巨噬细胞。

Apoptotic cells significantly increase in the premature calcific placenta and it may play an important role in the pathophysiologic mechanisms of premature calcification of placenta.

提前钙化胎盘组织中细胞凋亡增多，细胞凋亡可能在胎盘提前钙化的发生发展过程中起了重要作用。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。