亡

In order to evaluate the roles played by telomerase activity and apoptosis gene in malignant transformation of mammary atypical ductal hyperplasia, as well as the ultrastructure characteristic and regular pattern in the transformation, we investigated the expression of telom- erase genes and apoptosis related genes (p53 and bcl-2) and ultrastructure characteristic in precancerous lesion-mammary atypical ductal hy- perplasia, and compared with breast carcinoma and benign hyperplasia.

本文研究端粒酶基因、凋亡相关基因（p53、bcl-2）在乳腺癌前病变-乳腺导管非典型增生中的表达情况，探讨乳腺导管非典型增生上皮的超微结构特征，并与乳腺癌、乳腺导管单纯性增生进行对比，旨在研究端粒酶活性变化及凋亡相关基因在乳腺导管非典型增生上皮细胞癌变过程中的作用及意义，并研究乳腺导管非典型增生上皮细胞恶性转化过程中的形态结构特点及变化规律。

The serum levels of the patients in non remission were significantly higher than that of the control.

近来 ，随着对细胞凋亡的认识，发现细胞凋亡在白血病缓解过程中起着重要作用。

AIM: To study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.

目的：探讨肿瘤坏死因子相关诱导凋亡配体蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。

METHODS: RAW264.7 macrophages growth inhibition was measured by MTT assay. The apoptosis effect of RAW264.7 murine macrophages induced by ox-LDL was analyzed by flow cytometric analysis and DNA agarose electrophoresis. After expression of Daxx was silenced by special siRNA, the macrophages apoptosis was observed by AO/EB fluorescence staining. Oil Red O Dyeing experiment was used to show the cellular lipid droplets in lipid-loaded cells. High performance liquid chromatography analysis was performed to determine the content of cellular cholesterol. Real time RT-PCR was used to detect the mRNA expressions of Daxx and SCAP.

用不同浓度的氧化型低密度脂蛋白处理RAW264.7细胞48h，MTT法检测ox-LDL对RAW264.7细胞生长的影响；流式细胞术和DNA断裂片段分析法研究ox-LDL诱导的细胞凋亡；用特异性siRNA沉默Daxx在RAW264.7细胞中的表达，通过AO／EB染色观察基因沉默后的细胞凋亡形态学改变；高效液相色谱检测细胞内胆固醇含量；油红O染色观察细胞内脂滴的形成情况；Real time RT-PCR检测细胞内Daxx mRNA、SCAP mRNA的表达情况；用Western Blot印迹法检测caveolin-1蛋白的表达。

Methods Silence the expression of RhoC gene in Bel7402 cells by RNAi. Determine the levels of apoptosis gene and apoptosis-related gene by FACS and RT-PCR, and the migration and growth of cells by scarification healing test and soft agar clone formation test.

以RNAi沉默Bel7402细胞RhoC基因的表达，FACS和RT-PCR检测细胞凋亡和凋亡相关基因水平，细胞划痕损伤和软琼脂克隆形成试验检测细胞迁移和生长特性。

Sodium selenite can induce the apoptosis of SGC7901 cells, which is associated with the blockage of cell cycle.

亚硒酸钠能够诱导SGC7901细胞凋亡，亚硒酸钠诱导SGC7901细胞凋亡与细胞周期阻滞密切相关。

To investigate whether sodium selenite can efficiently induce SGC7901 cells, and to study the relationship between the apoptosis and the cell cycle.

目的：探讨亚硒酸钠能否诱导胃上皮肿瘤SGC7901细胞凋亡，以及凋亡诱导与细胞周期改变的关系。

Apoptotic index, the expression of Bax and Bcl-2 protein in myocardium were analyzed semiquantitatively by TUNEL and immunohistochemical assay 1,2,4,6,8,10,12 hours after coronary ligation.

2应用TUNEL法和免疫组织化学方法检测实验性大鼠AMI过程中心肌细胞凋亡及凋亡相关蛋白Bcl-2和Bax的表达情况。

OBJECTIVE:To explore the expression of the apoptosis inhibiting gene and its mechanism of inhibiting apoptosis during the development of tree shrew liver cancer.

目的：利用实验诱发树鼠句肝癌的动物模型，动态研究在树鼠句肝癌形成过程中凋亡抑制基因的表达及其抑制凋亡的机制。

Nano-Fe_3O_4 can induce DNA single-strand breaks without significancy and can not induce micronuclei formation and percentage of apoptosis. Nano-Fe_3O_4 can aggravate the effect of CdCl2 on DNA single-strand breaks and chromosome damage in HepG2 cells. They showed synergistic effects on DNA single-strand breaks after the data were statistic analyzed.

结果发现CdCl2能引起DNA断裂损伤、微核率的增加和细胞凋亡率的增加；nano-Fe_3O_4能引起DNA断裂损伤增加，但无显著意义，未引起微核率和细胞凋亡率的增加；nano-Fe_3O_4能加重CdCl2的对细胞DNA断裂损伤和染色体损伤，且二者联合作用对DNA断裂损伤的结果经统计分析认为有协同作用。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。