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Methods: We divide the rats into 5 groups in random, with Morris method, detect the change of some active oxygen radicals such as super-oxide demitasse, Nitric Oxide Synthase, malondialdehyde etc. Also, we detect the change of cholinesterase, Monoamine Oxidize; using HE,PAS staining, immuno-histochemical technique, detect hippocampus CA1 cerebral pathology slices optical density value of NOS, CHE and lipofuscin of neural cell; detecting apoptosis rate and the expression of P53 , which are neuronal apoptosis related genes.

大鼠随机分为5组,采用"Morris水迷宫"法观察脑缺血性模型大鼠学习记忆功能,检测超氧化物歧化酶、一氧化氮合酶、丙二醛等自由基代谢异常的改变,检测胆碱酯酶、单胺氧化酶等老化相关酶的变化、脑组织神经细胞免疫组织化学技术、检查海马CA1区脑组织的病理切片,检测NOS、CHE光密度值;流式细胞技术:检测细胞凋率,及促细胞凋基因、P_(53)蛋白表达;病理切片采用HE染色、PAS染色及免疫组化法检查,检测对大鼠海马神经元细胞一般病理变化及脑细胞内脂褐含量。

Results After articular cartilage injury, the degeneration and denature of the cartilage occurred, and the cluster expressed collagen type Ⅹ and apoptosis appeared.Conclusion Apoptosis may play a key role in the pathogenesis and prognosis of osteoarthritis.

为进一步探讨骨关节病的发病机制,我们收集了骨关节病的临床标本,采用原位杂交及原位末端标记的方法,观察Ⅹ型胶原和凋细胞在骨关节病关节软骨组织中的分布,并探讨凋与骨关节病的关系。

It suggested that the disbalance between proliferation and apoptosis which might be relative to abnormal expression of c-myc may contribute to pulmonary vascular structural remodeling.

提示增殖和凋现象共存在于正常和处理大鼠的肺血管细胞中,也许c-myc等基因的导常表达导致了细胞增殖和凋的失衡,进而调节了慢性低氧肺血管结构的改建。

In this report, the 59Tc labelling of Annexin V fragment modified with HYNIC (HYNIC-Anx13) using Tricine, EDDA or EDDA/Tricine as coligands was described. The effect of various factors on 99Tc labelling was investigated. Biodistribution studies in normal mice and gamma imaging of apoptosis in rats induced by cyclophosphamide were performed.

为探讨99Tc标记的HYNIC-Anx13用于细胞凋显像的可能性,分别以N-[三甲基]甘氨酸,乙二胺-N,N'-二乙酸和EDDA/Tricine为协同配体,对经6-肼基烟酰基修饰的膜联蛋白V片段(HYNIC-Anx13)的99Tc标记条件和主要影响因素进行了研究,并完成了HYNIC-Anx13的99Tc标记物在正常小鼠体内的生物分布和大鼠细胞凋模型的显像实验。

Objective To investigate the expression and significance of regulators and effector of Survivin and Caspase??

目前对宫颈癌的发生、发展已进行多方面的研究, Survivin 是凋抑制蛋白家族的一个新成员,是迄今发现最强的凋抑制因子。

The effects of IR and IP on hemodynamics, epicardial electrography, myocardial infarct size, cardiomyocytic apoptosis and gene proteins involving apoptosis (Fas, Bcl-2 and Bax) are observed in aneasthetized rabbit myocardium.

在麻醉家兔心肌IR模型上,观察IR和IP对血流动力学、心外膜电图、心肌梗死范围、心肌细胞凋和凋相关调控基因蛋白(Fas、Bcl-2、Bax等)的影响。

The effects of myocardial ischemia-reperfusion and RIP on hemodynamics, epicardial electrography, myocardial infarct size, cardiomyocytic apoptosis and gene proteins involving apoptosis (Fas, Bcl-2 and Bax) are observed in aneasthetized rabbit myocardium.

在麻醉家兔心肌IR(myocardial ischemia-reperfusion,MIR)模型上,观察MIR和肾脏IP(renal ischemic preconditioning,RIP)对血流动力学、心外膜电图、心肌梗死范围、心肌细胞凋和凋相关调控基因蛋白(Fas、Bcl-2、Bax等)的影响。

Department of Physiology, Institute of Basic Medicine,Hebei Medical University, Shijiazhuang 050017Abstract: The effects of ischemia-reperfusion and ischemic preconditioning on hemodynamics, epicardial electrography, myocardial infarct size, cardiomyocytic apoptosis and gene proteins involving apoptosis (Fas, Bcl-2 and Bax) were observed in aneasthetized rabbit myocardium.

在麻醉家兔心肌缺血-再灌注(ischemia-reperfusion,IR)模型上,观察IR和缺血预处理(ischemic pre~con~ditioning, IP)对血流动力学、心外膜电图、心肌梗塞范围、心肌细胞凋和凋相关调控基因蛋白(Fas、 Bcl-2、 Bax等)的影响。

WE used different power of semiconductor Laser to irradiate the black hair canine to observe and evaluatr the tissue effects with electroscope,flow cytometry and Tunel technique at different period pf time after irradiation.

分别在治疗即刻、治疗后不同时期通过电镜、流式细胞术、TdT介导的RdUTP缺口末端标记法对比治疗效果,观察组织变化及其可能存在的凋改变,并初步探讨诱导细胞凋的机制及临床治疗意义。

Methods To establish asphyxia models of low degree,moderate degree and severe degree of SD,collected samples of gastric mucous membranes,and by using electroscope and DNA electrophoresis to examine cell appotosis;by using RNA dot blot and immunohistochemistry to examine expressed levels of fas gene and FAS protein.

方法用20只新生SD大鼠建立轻、中、重度窒息模型,采集胃粘膜标本,分别进行电镜、DNA电泳检测细胞凋是否存在;采用RNA打点杂交及免疫组化技术检测凋基因窒息模型。

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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。

This is not paper type of business,it's people business,with such huge money involved.

这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。